Temozolomide administered to patients with glioblastoma at full actual body weight dosing during the concurrent phase is necessary to achieve a median overall survival (OS) that is similar to that seen in a previous trial, according to a recent study.
The circulating levels of microRNA (miR)-146a is a potential noninvasive biomarker for the diagnosis and prognosis of acute lymphoblastic leukaemia (ALL) in both paediatric and adult patients, a recent study has found.
Prostate-specific antigen (PSA) screening was associated with similar decrease in incidence of advanced prostate cancer (PCa) among statin users vs nonusers, but less detection of low-grade localized tumours in the former than the latter — indicating that statin does not compromise the benefits of PSA-based screening while also conferring the benefit of less overdiagnosis of low-risk tumours.
Treatment with docetaxel appears beneficial in patients with low- and high-burden metastatic hormone-sensitive prostate cancer, a study has shown. However, no consistent differences for overall survival are seen in subgroup analyses as regards volume of metastatic disease.
Nivolumab is a promising therapy for patients with thymic epithelial tumours who have received multiple-line treatments, suggests a study. However, the high rate of severe toxicities specifies a need to find out a reliable marker to predict patients who will derive benefit or exhibit toxicity.
Cancer is frequently misdiagnosed as tuberculosis (TB) in children due to the clinical and radiologic overlap of the two diseases, which then contributes to increased mortality in this population, reveals a recent study.
High consumption of vegetables and fruits is found to be positively associated with quality of life (QoL), cognitive, physical and emotional functioning, as well as less severe symptoms of nausea, vomiting, dyspnoea, diarrhoea, loss of appetite, insomnia and constipation in Chinese women with early-stage breast cancer, researchers at the Chinese University of Hong Kong (CUHK) and Princess Margaret Hospital (PMH) have reported.
An early, structured, progressive exercise is safe and effective for women at high risk of developing shoulder and upper limb problems following nonreconstructive breast cancer surgery, evidence from the UK PROSPER study shows.