A recent study suggests the use of Mohs micrographic surgery (MMS) for eyelid sebaceous carcinoma (SC) without orbital involvement to help prevent its recurrence. However, MMS has not succeeded in changing the long-term outcomes regarding metastasis or tumour-related mortality.
Cabozantinib is not better than mitoxantrone-prednisone at relieving pain in patients with metastatic castration-resistant prostate cancer (mCRPC) with symptomatic bone metastasis, a recent study suggests.
Treatment with abiraterone leads to fewer health-related quality of life (HRQoL) and mental health issues than enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC), a recent study has found.
A recent phase Ib study has identified the maximum tolerated dose (MTD) of the combination therapy of entinostat, lapatinib and trastuzumab, which provides acceptable tolerability and antitumour activity in heavily pretreated patients with human epidermal growth factor 2 (HER2)-positive metastatic breast cancer. This also supports a confirmatory trial.
A two-step algorithm that incorporates the liver stiffness measurement hepatocellular carcinoma (LSM-HCC) score and enhanced liver fibrosis (ELF) score appears to improve the accuracy of predicting HCC in chronic hepatitis B (CHB) patients after antiviral treatment, according to a study from Hong Kong.
Transgender women (male sex assigned at birth, female gender identity) are at greater risk of breast cancer than cisgender men, while transgender men (female sex assigned at birth, male gender identity) are at lower risk compared with cisgender women, a recent study has shown.
Gilteritinib, a novel inhibitor of the tyrosine kinase FLT3, improves survival outcomes among patients with relapsed or refractory acute myeloid leukaemia (AML) with FLT3 mutations vs standard chemotherapy, according to results of the phase III ADMIRAL trial reported at the American Association for Cancer Research (AACR) Annual Meeting 2019 held in Atlanta, Georgia, US.
Patients with advanced small cell lung cancer (SCLC) who experience disease progression despite two or more lines of therapy could benefit from pembrolizumab in the third-line setting, according to results from the phase 1b KEYNOTE-028 and phase II KEYNOTE-158* studies presented at AACR 2019.