A large retrospective cohort study by the University of Hong Kong (HKU) finds that postoperative prescription of opioids is associated with increased risks of new persistent opioid use, 30-day emergency department visits, 30-day readmission, and 30-day all-cause mortality.
Pretreatment level of serum carcinoembryonic antigen (CEA) is independently associated with overall and disease-free survival among patients with nonsmall cell lung cancer (NSCLC), reports a study. The same marker is also used for the prognosis of patients with the same pathologic stages.
Faecal immunochemical test (FIT) appears to provide useful information regarding a patient’s risk of advanced neoplasia and subsequently help physicians decide which patients should be prioritized for a colonoscopy, according to a study.
In the merged analysis of the IMpower133 trial and IMbrella A open-label extension study, the combination of the PD-L1 inhibitor atezolizumab and a chemotherapy regimen comprising carboplatin and etoposide (CP/ET) demonstrated potential for survival benefit of up to 5 years in patients with extensive stage-small-cell lung cancer (ES-SCLC).
Adding subablative stereotactic body radiotherapy (SBRT) concurrently to immune checkpoint inhibitor (ICI) monotherapy does little to improve survival outcomes in patients with advanced solid tumours, as shown in the phase II CHEERS trial.