Dr. Min Han Tan, Dr. Song Ling Poon, Prof Winnie Yeo, 20211208000000
Homologous recombination repair deficiency (HRD) testing informs treatment decisions in ovarian cancer (OC) and predicts the magnitude of benefit from poly(ADP-ribose) polymerase (PARP) inhibitors, such as niraparib. At a webinar, Professor Winnie Yeo of the Department of Clinical Oncology, Chinese University of Hong Kong, discussed the role of HRD testing in OC management, while Dr Min-Han Tan of Lucence Group and Dr Song-Ling Poon of ACT Genomics reviewed the HRD score algorithms and testing platforms currently available in Hong Kong.
Increased serum iron or transferrin saturation levels in individuals with non-alcoholic fatty liver disease (NAFLD) may point to an increased risk of hepatocellular carcinoma (HCC), according to a study presented at The Liver Meeting Digital Experience™.
In patients with soft tissue sarcoma (STS), preoperative radiation therapy (RT) performed at an academic cancer centre, as opposed to those done at a community centre, results in fewer wound complications following resection, according to a study.
An observational single-institution cohort study provides evidence that levetiracetam use throughout the duration of standard chemotherapy is associated with longer median overall survival (OS) in patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma.
Poor environmental quality is associated with greater odds of an advanced stage prostate cancer at diagnosis, with a study finding the strongest associations for lower water, land, sociodemographic quality.
In the second-line treatment of patients advanced oesophageal cancer, the use of programmed cell death 1 (PD-1) inhibitors yields more favourable outcomes than chemotherapy across multiple patient subgroups, according to the results of a meta-analysis.