Dr Ravichandran Nadarajah, a consultant at the Department of Obstetrics & Gynaecology, Singapore General Hospital, speaks to Roshini Claire Anthony on the importance of early diagnosis and prevention of cervical cancer.
Dr Ravichandran Nadarajah, a consultant at the Department of Obstetrics & Gynaecology, Singapore General Hospital, speaks to Roshini Claire Anthony on the significant role played by GPs in ensuring early diagnosis and prevention of cervical cancer.
According to the Singapore National Registry of Diseases Office (NRDO), prostate cancer is the third most common cancer and the sixth most common cause of cancer-related deaths affecting men in Singapore. Dr Daniel Tan, radiation oncologist and medical director of Asian American Radiation Oncology at Gleneagles Hospital, Singapore, speaks to Roshini Claire Anthony on the importance of early detection of prostate cancer and the challenges associated with diagnosing and treating this condition.
A 55-year-old man presented with almost one year history of heat intolerance, mild palpitation and significant weight loss. Free T3 and T4 were elevated with normal TSH. Patient had suboptimal response to carbimazole therapy.
Lung cancer still poses a challenge in terms of diagnosis and treatment. In many countries in Asia, the condition remains a significant cause of mortality. The prevalence of tuberculosis in the region also confounds this problem, which necessitates a highly efficient means to differentiate these two entities. Electromagnetic navigation bronchoscopy (ENB), a state-of-the-art lung biopsy technique, was recently introduced in Hong Kong, placing the city as a pioneer in its utilization in the region. Dr Chung-Ming Chu, Specialist in Respiratory Medicine in Hong Kong, discusses the role of ENB in diagnosing pulmonary lesions and shares his experience on its use.
A 73-year-old man presented with 1 week’s history of progressive epigastric pain. The pain was dull in nature and the patient reported no vomiting or radiation of pain. On presentation, the patient was found to have a low-grade fever (temperature, 37.8°C). There was no tea-coloured urine. The patient had enjoyed good past health except for a previous surgery for spinal injury.
Melasma is a benign pigmentary skin disorder. However, it features prominently on sun-exposed areas, typically the face and arms, and as such affects the quality of life of those with the disorder. Radha Chitale spoke with Dr. Gavin Ong Chun Wei, a dermatologist at The Skin Specialist clinic in Singapore, about how GPs can best diagnose and treat patients with melasma.
Dr. Cheah Yee Lee, a liver transplant and hepatopancreatobiliary surgeon at Gleneagles Hospital, Singapore spoke to Roshini Claire Anthony on how GPs can help with early detection of pancreatic cancer and improve outcomes for patients.
Taiwan and Singapore retain top rankings in palliative care in Asia, but Hong Kong has been overtaken by Japan and South Korea, descending from the 3rd position in Asia in 2010 to the 5th position, according to the latest 2015 Quality of Death Index released by The Economist Intelligence Unit.
Targeting the immune system has emerged as an encouraging strategy for a broad range of malignancies. In lymphoma, evidence of the expression of programmed death-1 (PD-1) and PD ligand 1 (PD-L1) has led to the development of a growing number of immune checkpoint inhibitors that are demonstrating promise in early clinical trials.
Tisagenlecleucel, now US FDA approved, has made history as the first ever chimeric antigen receptor (CAR) T-cell therapy for B-cell precursor acute lymphoblastic leukaemia (ALL) – a breakthrough that has the potential to transform treatment for blood cancers that have not responded to standard therapies.
Colorectal cancer (CRC) is one of the most common cancers worldwide and its incidence is rising among Asians. Long-term survival outcomes are poor for CRC because patients often remain undiagnosed until the disease has reached an advanced stage. Panitumumab, a human IgG2 monoclonal antibody with high binding affinity for epidermal growth factor receptors, has shown encouraging results in the treatment of metastatic CRC (mCRC).