Clinical trials of chimeric antigen receptor (CAR) T-cell therapy in haematological malignancies are to commence in Hong Kong following completion of the city’s first CAR T-cell laboratory to be built by the Chinese University of Hong Kong (CUHK).
Dr. Bryan Li, Dr. Gerry Kwok, Dr. Thomas Yau, 20190807035449
Case 1: A 59-year-old gentleman with advanced HCC was referred to our centre for management. He had a history of diabetes, hypertension and ischaemic heart disease. He was a nondrinker and not a carrier of hepatitis B or C.
Case 2: A 65-year-old man with a history of alcoholic cirrhosis and oesophageal varices was found to have rising AFP levels on routine follow-up. He also had a 3-year history of diabetes and was on diet control, with an HbA1cof 6.2 percent and fasting glucose of 6.8 mmol/L. He did not need any diabetic medications.
The US Food and Drug Administration (FDA) has given the greenlight to pembrolizumab as a monotherapy for recurrent locally advanced or metastatic squamous cell carcinoma of the oesophagus whose tumours express PD-L1.
New drug applications approved by US FDA as of 16 - 31 July 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
A recently published analysis of the world’s largest genome-wide association study (GWAS) of lung cancer among female never-smokers found a set of tuberculosis (TB)-related genes associated with lung adenocarcinoma in Asian women.
Human papillomavirus (HPV) vaccination significantly reduces the frequency of genital HPV 16 and 18 infections and cervical intraepithelial neoplasia grade 2+ (CIN2+) in young women and shows signs of herd effects with a reduced frequency of anogenital warts in both young women and men, a recent study showed.
Annual breast cancer screening with magnetic resonance imaging (MRI) led to detection of fewer late-stage and node-positive cancers than annual mammography, according to the FaMRIsc* study from the Netherlands. However, specificity was lower and number of false-positives higher with MRI vs mammography.