Use of statins appears to reduce the risk of developing hepatocellular carcinoma in patients with nonalcoholic fattly liver disease (NAFLD), whereas hypertension conferred a risk increase, according to a retrospective case-control study.
Salvage radical prostatectomy results in better functional outcomes and has a low risk of major complications as compared to those previously reported, a study claims. Furthermore, robotic salvage radical prostatectomy appears to reduce anastomotic stricture, blood loss and hospital stay, and improve continence outcomes.
A higher Genomic Prostate Score (GPS) is a predictor of an increased risk of adverse pathology in patients who undergo radical prostatectomy after a period on active surveillance, as in those who undergo immediate prostatectomy, reports a study. The GPS is also associated with biochemical recurrence after radical prostatectomy.
Any gastrointestinal or genitourinary bleeding carries a 20–30-fold higher hazard for new cancer diagnosis in the respective organ systems in patients with atherosclerosis receiving antithrombotic drug treatment, as shown in a recent study.
In pancreatic cancer patients undergoing chemotherapy, the presence of diabetes mellitus is associated with reduced survival and larger tumour, as well as with increased risk of death after treatment, according to a meta-analysis.
An elevation in international normalized ratio (INR) has been observed within 2 weeks of the start of concomitant therapy with warfarin and tyrosine kinase inhibitors (TKI; gefitinib or erlotinib), reports a recent study.
New drug applications approved by US FDA as of 01 - 15 October 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.