A 55-year-old man presented with almost one year history of heat intolerance, mild palpitation and significant weight loss. Free T3 and T4 were elevated with normal TSH. Patient had suboptimal response to carbimazole therapy.
A 73-year-old man presented with 1 week’s history of progressive epigastric pain. The pain was dull in nature and the patient reported no vomiting or radiation of pain. On presentation, the patient was found to have a low-grade fever (temperature, 37.8°C). There was no tea-coloured urine. The patient had enjoyed good past health except for a previous surgery for spinal injury.
Krukenberg tumour is a metastatic signet ring cell adenocarcinoma of the ovary. This tumour is uncommon, accounting for 1–2% of all ovarian tumours. The stomach is the primary site in most Krukenberg tumour cases (70%), and the prognosis is generally poor. We report a case of a pregnant lady who was incidentally found to have a large ovarian mass during caesarean section which was later confirmed to be a Krukenberg tumour.
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Cancer drugs approved by the European Medicines Agency (EMA) from 2009 to 2013 have been sold in the market even without evidence of benefit on survival or quality of life (QoL), according to a study. Survival gains over existing treatment options or placebo, if any, are usually marginal.