Stereotactic ablative radiotherapy (SABR) has shown promising results in primary renal cell carcinoma (RCC) in recent trials and has become a treatment option for patients with inoperable primary RCC or tumours in solitary kidney, said Dr Shankar Siva of the Peter MacCallum Cancer Centre of Melbourne, Australia, at the Uro-Oncology Asia 2020 conference.
Olaparib, a poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor, represents a paradigm shift in management of metastatic castration-resistant prostate cancer (mCRPC) in view of the promising results shown in recent trials, said Professor Przemyslaw Twardowski of John Wayne Cancer Institute of Santa Monica, California, US, who spoke at the Uro-Oncology Asia 2020 conference.
Immunotherapy-chemotherapy combinations, immunotherapy doublets, and combinations of immunotherapy with novel targeted agents are emerging as strategies for management of metastatic urothelial carcinoma (mUC) in view of the limitations with chemotherapy and single-agent immunotherapy, said an expert at the Uro-Oncology Asia 2020 conference.
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The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Weight suppression appears to result in future onset of eating disorders characterized by dietary restriction or compensatory weight control behaviours, suggesting weight-suppressed women represent an at-risk group that may benefit from selective prevention programmes, a study has found.