Kidney transplantation in hepatitis B virus (HBV)-infected donors and/or recipientshas become possible with the advent of antiviral therapies, but nephrologists should be aware of the potential risks of HBV flare and ensure that timely preventive measures are instituted.
Studies on the inorganic compound sodium zirconium cyclosilicate and the hypoxia inducible factor prolyl hydroxylase (HIF-PH) pathway inhibitor roxadustat have shown efficacy and safety for the management of hyperkalaemia and anaemia, respectively, among chronic kidney disease (CKD) patients.
Most immune-related toxicities resulting from lung cancer immunotherapy usually involve the skin, lungs, endocrine system and the gastrointestinal (GI) tract and are manageable with immunomodulatory agents such as corticosteroids.
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Results of the registrational phase I/II ARROW trial of pralsetinib, presented at the European Society for Medical Oncology (ESMO) Virtual Congress 2020, reveal overall response rates (ORRs) of ≥60 percent in pretreated and treatment-naïveRET-mutated (RETmut) medullary thyroid cancer (MTC) patients.