Kidney transplantation in hepatitis B virus (HBV)-infected donors and/or recipientshas become possible with the advent of antiviral therapies, but nephrologists should be aware of the potential risks of HBV flare and ensure that timely preventive measures are instituted.
Studies on the inorganic compound sodium zirconium cyclosilicate and the hypoxia inducible factor prolyl hydroxylase (HIF-PH) pathway inhibitor roxadustat have shown efficacy and safety for the management of hyperkalaemia and anaemia, respectively, among chronic kidney disease (CKD) patients.
Most immune-related toxicities resulting from lung cancer immunotherapy usually involve the skin, lungs, endocrine system and the gastrointestinal (GI) tract and are manageable with immunomodulatory agents such as corticosteroids.
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Transitioning from bortezomib- to ixazomib-based induction is feasible, tolerable and effective in the treatment of community patients with newly diagnosed multiple myeloma (NDMM), according to a study presented at the 61st Annual Meeting of the American Society of Hematology (ASH 2019).
Final analysis of the POEMS (Prevention of Early Menopause) study finds that breast cancer (BC) patients treated with the gonadotrophin-releasing hormone agonist (GnRHa) goserelin, in addition to chemotherapy, are more likely to avoid premature menopause and to become pregnant without negatively impacting disease-related outcomes.
In breast cancer, especially hormone-negative tumours, an ultrasound-guided core biopsy (CNB) is useful for predicting pathologic complete response (pCR) to chemotherapy and may thus help to avoid surgery for some patients, a study has found.
Circulating miR-155 may be potentially used as a diagnostic and therapeutic monitoring marker in breast cancer, suggests an Indonesian study presented at the 2019 Asia Congress of the European Society for Medical Oncology (ESMO Asia 2019).