Kidney transplantation in hepatitis B virus (HBV)-infected donors and/or recipientshas become possible with the advent of antiviral therapies, but nephrologists should be aware of the potential risks of HBV flare and ensure that timely preventive measures are instituted.
Studies on the inorganic compound sodium zirconium cyclosilicate and the hypoxia inducible factor prolyl hydroxylase (HIF-PH) pathway inhibitor roxadustat have shown efficacy and safety for the management of hyperkalaemia and anaemia, respectively, among chronic kidney disease (CKD) patients.
Most immune-related toxicities resulting from lung cancer immunotherapy usually involve the skin, lungs, endocrine system and the gastrointestinal (GI) tract and are manageable with immunomodulatory agents such as corticosteroids.
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Drawing from experience as a key investigator in landmark
clinical trials (including PALOMA, MONALEESA and
MONARCH), and his clinical experience with
CDK4/6 inhibitors, Dr Rafael Villanueva Vázquez shares his
insights into the current evidence of using CDK4/6 inhibitors
to treat HR+/HER2- ABC.