Use of a water-impermeable, friction-reducing barrier film (BF) may reduce skin toxicity (eg, radiation dermatitis, burning, and pruritus) on high-friction breast regions in women with breast cancer receiving post-lumpectomy adjuvant radiation therapy, according to a study.
Measuring the ratio of the soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) improves the accuracy of identifying pre-eclampsia without changing admission rates, according to the results of a trial.
Patients with HER2+ breast cancer with disease progression despite ≥2 lines of HER2-directed therapy may improve their progression-free survival (PFS) with the addition of neratinib than lapatinib to capecitabine, according to the phase III NALA* trial.
Infection with hepatitis B virus (HBV) does not appear to independently affect pregnancy outcomes, although it contributes to prolonged infertility, higher odds of secondary infertility, ovulatory disorders and reduced implantation rate, a study has found.
Consuming polyphenol-rich pomegranate juice during pregnancy was associated with better microstructural development and functional connectivity in the brains of newborns with intrauterine growth restriction (IUGR), suggests preliminary evidence from a pilot randomized study.
Pregnancy attenuates the risk of endometrial cancer regardless of whether it ends shortly after conception or at 40 weeks of gestation, a study has shown. A biological process occurring within the first weeks of pregnancy drives this risk reduction, as shown by pregnancies terminated through induced abortions having similar risk reductions as those ending in childbirth.
Children born to women receiving dolutegravir-based antiretroviral therapy (ART) for HIV since conception have an uptick of neural-tube defects compared with those whose mothers took non-dolutegravir ART at conception, additional follow-up data from the Tsepamo surveillance study show.
Administering intranasal desmopressin to patients with renal dysfunction not requiring haemodialysis reduces bleeding complications during renal biopsies, especially minor complications such as perinephric haematomas, a study has found. However, it may increase the risk of incident hyponatraemia.
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.