Pregnancy attenuates the risk of endometrial cancer regardless of whether it ends shortly after conception or at 40 weeks of gestation, a study has shown. A biological process occurring within the first weeks of pregnancy drives this risk reduction, as shown by pregnancies terminated through induced abortions having similar risk reductions as those ending in childbirth.
Children born to women receiving dolutegravir-based antiretroviral therapy (ART) for HIV since conception have an uptick of neural-tube defects compared with those whose mothers took non-dolutegravir ART at conception, additional follow-up data from the Tsepamo surveillance study show.
Having identified the prevalence and increased risk of masked hypertension in pregnant women, a recent study suggests that an office blood pressure (BP) of at least 125/75 mm Hg in the second half of gestation may be appropriate to indicate out-of-office measurements in high-risk pregnancies.
Lower age at onset of first menstruation poses an increased risk of type 2 diabetes mellitus (T2DM) later in life, possibly driven by adult body mass index (BMI), whereas later menarche is associated with reduced diabetes risk, a study has found.
The immunotherapeutic human papillomavirus (HPV) vaccine tipapkinogen sovacivec (TS) provided complete histologic resolution of cervical intraepithelial neoplasia (CIN) grade 2/3, offering a potential nonsurgical option for cervical precancerous lesions which could stretch to other HPV-associated precursors or cancers in the future, a new study shows.
Women who have premature ovarian insufficiency and are receiving hormone therapy (HT) appear to have poor sleep quality, taking longer to fall asleep and experiencing greater fatigue, according to a recent study.
Use of antiepileptic drugs (AEDs) during pregnancy was significantly associated with an increased risk of language delay in offspring at 5 and 8 years of age, according to a study presented at EAN 2019.
Supplemental folate intake appears to mitigate the adverse effect of exposure to raised levels of nitrogen dioxide on the likelihood of a live birth in women undergoing assisted reproductive technologies, according to a study.
Oral solithromycin may not be a suitable substitute for ceftriaxone plus azithromycin in the first-line treatment of uncomplicated genital gonorrhoea, according to results of the phase III SOLITAIRE-U* trial.
Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.