A systematic review and meta-analysis reveals that trials on prenatal vitamin D supplementation are being published at an accelerating pace but are generally of low quality, small and rarely designed to examine clinical outcomes.
A team of experts has just launched Hong Kong’s first collaborative pharmacogenomics study using next-generation sequencing (NGS) technology to identify mutation targets in patients with treatment-resistant/relapsed ovarian cancer (OC) towards a more personalized approach in management.
Coffee drinking appears to be generally safe within usual levels of intake and is more likely to benefit health than harm, except during pregnancy and in women at increased risk of fracture, according to the results of an umbrella review of meta-analysis of multiple health outcomes.
Fertility rates among women aged 15 to 49 registers a drop in the 2017 Malaysia Vital Statistics report and this drop is attributable to factors such as change of lifestyle, environmental and social stress; economic progression; and delay in childbearing among career-driven women, says a fertility expert.
Identification of BRCA mutation in ovarian cancer is vital because it allows better risk management and there is evidence that carriers may benefit from new treatment modalities, said Professor Woo Yin Ling, consultant gynaecological oncologist at the University of Malaya.
Human papillomavirus (HPV) infection is a prevalent disease worldwide. Consequences of HPV infection vary, depending on the infected individuals and the HPV genotype involved. Life-threatening consequences are not uncommon, and cervical cancer is a clear demonstration of the virus’s potency. While the incidence of cervical cancer is heavily concentrated on developing countries,1 the impact of HPV-related diseases on developed countries has not ceased. In the United States alone, HPV infections are the most common sexually transmitted disease with an estimated 5 million new cases being diagnosed in 2000 among young adults, incurring nearly US$3 billion in terms of direct medical costs.2 A multinational study involving 18,498 women showed that cervical HPV prevalence varied greatly geographically, ranging from the low of 1.6% in North Vietnam to the high of 27% in Nigeria. In general, HPV prevalence peaked among young, sexually active women and declined with age. In selected countries, however, a second peak was noted in women older than 55 years.3 The high prevalence of HPV-related diseases incurs a heavy burden on the healthcare systems of developed and developing countries alike, which renders HPV research and prevention a global public health imperative. On an individual level, the afflictions caused by HPV-related diseases go beyond that of physical suffering to affecting the psychological well-being of the infected. This is the focus of our paper.
Chronic hepatitis B virus (HBV) infection is a global problem. Chronic
HBV infection is probably the most common maternal infection encountered
in Hong Kong, China, and Southeast Asia. In Hong Kong, which is one of
the endemic areas, immunisation against HBV was first provided in 1983
to infants born to mothers who were screened positive for hepatitis B
surface antigen (HBsAg). Immunisation became widespread since November
1988, but HBsAg-positive mothers are still encountered frequently.1