Treatment with ospemifene is effective and safe in postmenopausal women with vulvovaginal atrophy, producing significant improvements in the number of vaginal superficial and parabasal cells, vaginal pH, and vaginal dryness severity, according to the results of a phase III trial.
A panel of four international and local experts shared the latest clinical evidence and discussed practical aspects on optimal patient care during a Malaysian Medical Association (MMA) workshop on iron deficiency and patient blood management.
In mothers chronically infected with hepatitis B virus (HBV), the presence of HBV DNA and hepatitis B e antigen (HBeAg) in the serum appears to be linked to cord blood viraemia in infants, according to a recent Singapore study.
A healthy lifestyle during the menopausal transition, as typified by abstinence from smoking, regular exercise, and a healthy diet, is associated with less development of subclinical atherosclerosis, according to data from the prospective SWAN* cohort.
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
Younger women with breast cancer who had a mastectomy demonstrated a worse quality of life (QoL) compared with those who underwent breast-conserving surgery (BCS), according to a study presented at SABCS 2018.
A pooled analysis of the European Organisation for Research and Treatment of Cancer (EORTC) 55971 trial and the Medical Research Council Chemotherapy Or Upfront Surgery (CHORUS) trial demonstrated that neoadjuvant chemotherapy and upfront debulking surgery result in similar overall survival (OS) in advanced tubo-ovarian cancer.
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
Treatment with secukinumab results in a higher rate of remission or low-disease activity at week 16 in patients with psoriatic arthritis as compared with placebo, according to a posthoc analysis of the FUTURE 2 study. This effect is sustained at 2 years and is evident in both tumour necrosis factor inhibitor-experienced and -naïve patients.