Dr. Carly Yanlin Wu, Assoc Prof. Daisy Kwai-Lin Chan, 20210308000000
Birth defects, also known as congenital anomalies, are abnormalities of body structure at birth which can lead to impaired function and physical disabilities. Children with birth defects may also have developmental or intellectual disabilities later on in life. These congenital anomalies can be major or minor in nature. The National Centre on Birth Defects and Developmental Disabilities in the US has defined major anomalies as anomalies with significant impact on the affected child that may require medical or surgical intervention, and minor anomalies as those having little impact on the affected child and requiring minimal intervention.1
Dr. Priyantha Ebenezer Edison, Assoc Prof. Daisy Chan Kwai Lin, 20201220000000
Thermoregulation is a key physiological challenge for all newborns
during their foetal to neonatal transition. Neonatal hypothermia is a
worldwide problem known to be associated with increased morbidity and
mortality. Inherent physiological limitations coupled with behavioural
and environmental factors of the delivery room place every newborn at
risk of hypothermia; however, with simple interventions, hypothermia can
be prevented in most instances.
Dr. Hang Wun Raymond Li, Prof. Pak-Chung Ho, Dr. Ernest Hung Yu Ng, 20200317000000
Anti-Müllerian hormone (AMH) was initially recognized as the factor that
determines regression of the Müllerian duct in the male foetus and
hence plays an important role in male sex differentiation. Production of
AMH in adult women was first reported in 1990.1 In the past two
decades, its role in female ovarian function and the clinical utilities
of serum AMH level has been increasingly studied.
Dr. Daniel Chan, Assoc Prof. Daisy Kwai-Lin Chan, 20200312000000
Hypoglycaemia is one of the most common clinical issues facing newborn
babies. It can be caused by abnormalities in the glycogen stores,
alternative substrates, and/or functioning enzymes. The definition of
neonatal hypoglycaemia itself remains challenging. Understanding normal
glucose physiology and biochemistry is important so that the
neonatologist can initiate appropriate investigations to elucidate an
aetiology and institute correct management. Early diagnosis and prompt
treatment of hypoglycaemia will reduce the risk of brain injury to the
Dr. Kubi Appiah, Dr. Piya Chaemsaithong, Dr. Liona Chiu Yee Poon, 20191129085839
Preterm birth (PTB) is birth that occurs before 37 weeks’ gestation, and it is a leading cause of perinatal morbidity and mortality.1 Babies born before 34 weeks’ gestation are particularly associated with high rates of morbidity and mortality.2 They are also at risk of long-term medical and social sequelae.3 It is therefore important to institute preventative measures that can help mitigate the occurrence of PTB in pregnant women.
Dr. Xian Li, Dr. Hang Wun Raymond Li, Dr. Shui Hua Lin, Prof. Pak-Chung Ho, 20190312084537
Endometrial polyp (EP) is a frequently encountered gynaecologic condition that may present with abnormal vaginal bleeding. It can also be asymptomatic and detected incidentally during imaging investigations or hysteroscopy for infertility or other conditions. Most EPs are benign, but premalignancy or even malignancy may occasionally occur.
Dr. Alvin Jia-Hao Ngeow, Assoc Prof. Daisy Kwai-Lin Chan, 20181210000000
Several methods are available to enhance placental transfusion to newly
born babies, including delayed cord clamping (DCC) and umbilical cord
milking (UCM). DCC refers to the clamping of the umbilical cord between
30 and 180 seconds after birth, as opposed to immediate cord clamping
(ICC). UCM, on the other hand, refers to stripping of the blood from the
umbilical cord and may be done from an intact or cut cord.