A conventional intervention promoting breastfeeding, healthy eating and physical activity in women during pregnancy has unexpectedly resulted in adverse long-term weight outcomes in their offspring, while a less conventional sleep intervention has maintained its positive outcomes at age 5 years, according to the results of a follow-up of the Prevention of Overweight in Infancy (POI) study.
An association exists between fatty acid desaturase (FADS) variants and gestation duration, suggesting that long-chain polyunsaturated fatty acids (LC-PUFAs) may play a potential role in gestation duration, reports a study that utilizes a Mendelian randomization approach.
Women with a history of acute kidney injury (AKI) before pregnancy, despite apparent full recovery, are at greater risk of pregnancy complications such as pre-eclampsia, a study has found. This risk is modified by severity of the AKI episode.
Ondansetron has been increasingly used for treating nausea and vomiting in pregnancy, and first-trimester exposure to the drug appears to pose no increased risk of birth defects, a study has found. However, there is a modest association found for cleft palate and renal agenesis–dysgenesis.
Age, weight, oral corticosteroid use and strenuous exercise at age 18 years appear to be useful in predicting the 5-year risk of height loss of at least 1 inch in postmenopausal women, according to a study.