Obstetrics & Gynaecology

Flu shot during pregnancy not tied to autism in offspring

Pearl Toh, 2 days ago

Having vaccination against influenza during pregnancy was not associated with an increased risk of autism spectrum disorder (ASD) in the offspring, a large cohort study reveals — providing more support for vaccination during pregnancy.

Novel non-hormonal therapy may reduce hot flashes, improve QoL in postmenopausal women

Roshini Claire Anthony, 4 days ago

NT-814, an oral, non-hormonal dual neurokinin 1,3 receptor antagonist may reduce the frequency of hot flashes, while improving quality of life (QoL) and sleep in postmenopausal women, according to results of the phase IIb SWITCH-1 trial presented at NAMS 2020.

Healthy lifestyle during pregnancy may prevent depression

Tristan Manalac, 4 days ago

Poor lifestyle during pregnancy, such as physical inactivity, inappropriate sleep and diet, and smoking, appear to aggravate the risk of developing depression, according to a recent Singapore study.

Maternal thyroid dysfunction ups risk of neurocognitive outcomes in offspring

5 days ago

Thyroid dysfunction during pregnancy is associated with several neurocognitive outcomes in the offspring, suggest the results of a study. Prompt examination and treatment on thyroid function is urged for pregnant women.

Acute diarrhoea is the second leading cause of death in children aged younger than 5 years, accounting for approximately 1.9 million deaths worldwide each year; however, diarrhoea is a preventable and treatable condition. In Malaysia, acute gastroenteritis accounts for about 1.3% of all deaths in children aged younger than 5 years annually. Diarrhoea is defined as the passage of three or more loose or watery stools within 24 hours, and it may be clinically categorised as either acute watery diarrhoea (AWD), acute bloody diarrhoea, persistent diarrhoea or diarrhoea with severe malnutrition.

01 Sep 2020

Acute diarrhoea is the second leading cause of deathin children aged younger than 5 years, accounting forapproximately 1.9 million deaths worldwide each year;however, diarrhoea is a preventable and treatable condition.In Malaysia, acute gastroenteritis accounts for about 1.3%of all deaths in children aged younger than 5 years annually.Diarrhoea is defined as the passage of three or more looseor watery stools within 24 hours, and it may be clinicallycategorised as either acute watery diarrhoea (AWD), acutebloody diarrhoea, persistent diarrhoea or diarrhoea withsevere malnutrition.

Expert consensus: Patient profile should guide antihistamine choice in primary care setting

10 Dec 2019

Oral H₁-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.

The Evolving Role of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in Women’s Urogenital Health

12 Jun 2019

Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.

Novel non-hormonal therapy may reduce hot flashes, improve QoL in postmenopausal women

Roshini Claire Anthony, 21 Oct 2020

Number, severity of menopausal symptoms may up CV risk

Roshini Claire Anthony, 19 Oct 2020

Women who experience two or more moderate or severe menopausal symptoms may have an elevated risk of cardiovascular disease (CVD) or strokes, according to a study presented at NAMS 2020.

Suvorexant beneficial for VMS-associated insomnia in midlife women

Audrey Abella, 13 Oct 2020

The dual orexin receptor antagonist suvorexant was effective in managing VMS*-associated insomnia among women in midlife, with further benefits for self-reported night-time, but not daytime, VMS, according to data presented at NAMS 2020.

Vaginal softgel benefits older women with vulvovaginal atrophy

Audrey Abella, 12 Oct 2020

Use of the self-administered TX-004HR – an applicator-free, ultra-low-dose, 17β-oestradiol softgel vaginal insert – led to significant improvements in the symptoms of vulvovaginal atrophy (VVA) such as moderate-to-severe dyspareunia and vaginal dryness in postmenopausal women aged >60 years, according to updated results from the phase III REJOICE trial presented at NAMS 2020.

Hormone therapy protects the heart by lowering inflammation

Pearl Toh, 10 Oct 2020

One way how hormone therapy with oestradiol may slow the progression of atherosclerotic cardiovascular disease (CVD) in postmenopausal women is through the reduction of inflammatory biomarkers, according to the ELITE* study presented at the NAMS 2020 Annual Meeting.

No benefit to endometrial scratching before first-cycle IVF/ICSI

Roshini Claire Anthony, 11 Sep 2020

Endometrial scratching prior to first cycle of in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) has no benefit on livebirth or clinical pregnancy rate, according to a study presented at ESHRE 2020.

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