The widely adopted practice of secondary surgical cytoreduction in women with platinum-sensitive recurrent ovarian cancer is being called into question as a phase III trial shows no improvement in overall survival (OS) with this approach.
The addition of pertuzumab to a trastuzumab-docetaxel regimen in the neoadjuvant setting improved total pathological complete response (tpCR) rates in Asian women with early or locally advanced ERBB2-positive breast cancer, according to the phase III PEONY trial from China.
Early menopause may be linked to an elevated risk of cardiovascular disease (CVD) before age 60 years, according to a recent analysis.
Gangliosides and docosahexaenoic acid (DHA) play critical roles in early childhood brain development.
Incorporating polygenic risk scores based on 18 SNPs (single nucleotide polymorphisms) into risk stratification for breast cancer will improve screening results, says an expert.
Making genetic testing mainstream, allows more patients to be tested, identifies more carriers and enables appropriate stratification of treatment and outcomes, says an expert.
Patients undergoing assisted reproduction for non-male factor infertility do not derive greater benefit from intracytoplasmic sperm injection (ICSI) over in vitro fertilization (IVF), according to a study presented at ESHRE 2019.
Likelihood of pregnancy following artificial insemination by donor (AID) or in vitro fertilization (IVF) was not negatively affected by using sperm that had been cryopreserved for up to 15 years, according to a study from China.
The likelihood of pregnancy following in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) is significantly reduced when male partners are aged 51 years and older, according to a retrospective study from the UK.