Obstetrics & Gynaecology

Top Medical News
Audrey Abella, Yesterday
Consuming caffeinated beverages* during pregnancy – even at levels below the ACOG**-recommended daily dose of 200 mg – may lead to small reductions in neonatal anthropometric measurements, according to a secondary analysis of the NICHD*** Foetal Growth Studies-Singletons.
Tristan Manalac, 2 days ago
Continuous monitoring skin temperature, through a wrist-worn device that records measurement during sleep, is more sensitive than basal body temperature (BBT) at detecting ovulation, according to a recent study.
2 days ago
Folic acid supplementation (FAS) around the time of pregnancy may help reduce the risk of nonsyndromic cleft lips or palates (NsCL/P) in offspring, a recent China study has found.
2 days ago
Obesity raises glycaemic level in pregnant women even if they have normal findings on a glucose tolerance test (OGTT), a recent study has found.
Jairia Dela Cruz, 4 days ago
Evaluating plasma kisspeptin levels, particularly during later gestational weeks of the first trimester of pregnancy, helps pinpoint women at risk of miscarriage, as shown in a study said to be the largest of its kind.
11 Jun 2021
Women with increasing age at menopause are at decreased risk of total and ischaemic stroke, a study has found.
Elvira Manzano, 09 Jun 2021
Children whose mothers had taken fish oil supplements during the second half of pregnancy appeared to have better problem-solving skills and attention focus at age 10 vs those whose mothers had consumed folic acid alone or no supplements at all in a study presented at WCPGHAN 2021.
Special Reports
Dr. Wong Seng Weng, Dr. Lee Guek Eng, 19 Mar 2021
In Singapore, advanced breast cancer (aBC) is the leading cause of cancer death in women 30–49 years of age. For premenopausal women diagnosed with hormone receptor (HR)-positive, HER2-negative BC, cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors provide new hope. Currently, ribociclib is the only CDK4/6 inhibitor studied in the first-line setting for premenopausal women with HR+/HER2- aBC, in the phase III MONALEESA-7 trial. Two experts, Dr Wong Seng Weng, Medical Director & Consultant Medical Oncologist at The Cancer Centre, Paragon Medical & Mount Elizabeth Novena Specialist Centre, and Dr Lee Guek Eng, Senior Consultant & Specialist in Medical Oncology at Icon Cancer Centre and Program Director of the Young Women Cancer Program, weigh in with their views on managing premenopausal women with aBC.
01 Sep 2020
Acute diarrhoea is the second leading cause of deathin children aged younger than 5 years, accounting forapproximately 1.9 million deaths worldwide each year;however, diarrhoea is a preventable and treatable condition.In Malaysia, acute gastroenteritis accounts for about 1.3%of all deaths in children aged younger than 5 years annually.Diarrhoea is defined as the passage of three or more looseor watery stools within 24 hours, and it may be clinicallycategorised as either acute watery diarrhoea (AWD), acutebloody diarrhoea, persistent diarrhoea or diarrhoea withsevere malnutrition.
12 Dec 2019
Rotavirus (RV) is highly contagious. Globally, 2 million children are hospitalized and more than 500,000 die annually from RV associated gastroenteritis. Therefore, vaccination is imperative for the prevention of RV infections.
10 Dec 2019
Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.
12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
01 Sep 2018

Gangliosides and docosahexaenoic acid (DHA) play critical roles in early childhood brain development. 

Dr Joslyn Ngu, 04 Dec 2017

Incorporating polygenic risk scores based on 18 SNPs (single nucleotide polymorphisms) into risk stratification for breast cancer will improve screening results, says an expert.

Conference Reports
Elvira Manzano, 09 Jun 2021
Children whose mothers had taken fish oil supplements during the second half of pregnancy appeared to have better problem-solving skills and attention focus at age 10 vs those whose mothers had consumed folic acid alone or no supplements at all in a study presented at WCPGHAN 2021.
Roshini Claire Anthony, 08 Jun 2021

Year 6 and 7 cumulative data from the Mirena Extension Trial suggest that the efficacy and safety of the levonorgestrel-releasing intrauterine system (LNG-IUS) as a contraceptive method is maintained over this time frame.

Elvira Manzano, 27 May 2021
Administration of mifepristone, followed by misoprostol, shortened induction-to-delivery intervals in women who lost their babies during the third trimester of pregnancy compared with misoprostol alone, results of a systematic review has shown.
Roshini Claire Anthony, 21 May 2021

The novel oral triterpenoid antifungal ibrexafungerp demonstrated superiority over placebo in reducing signs and symptoms of vulvovaginal candidiasis, according to results of the phase III VANISH-306 trial presented at ACOG 2021.

Roshini Claire Anthony, 19 May 2021

Women of reproductive age are often excluded from COVID-19 vaccine and treatment clinical trials, which could hinder their access to beneficial treatments, according to a study presented at the recent ACOG 2021 meeting.

Roshini Claire Anthony, 12 May 2021

Niraparib maintenance therapy improved progression-free survival (PFS) in patients with platinum-sensitive recurrent ovarian cancer (PSROC) regardless of time to progression since penultimate platinum chemotherapy or response to last chemotherapy, according to subgroup analyses of the NORA trial.

Pearl Toh, 07 May 2021
Hormonal therapy with a levonorgestrel-releasing intrauterine device (LNG-IUD) led to a high pathological complete response (pCR) rate in women with early-stage endometrial cancer, according to the feMMe trial presented at SGO 2021 Meeting.