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Novel tool predicts seizure risk in pregnant women with epilepsy
Stephen Padilla, 2 days ago
A simple 8-item prediction tool, the EMPiRE nomogram, operates well in calculating the risk of seizures in pregnant women with epilepsy who are prescribed antiepileptic drugs, according to a study. Integrating the tool within the antenatal booking visit may improve care in this population.
Epigenetic changes in womb may predict early-onset myopia
Tristan Manalac, 5 days ago
Epigenetic changes while inside the uterus may affect the likelihood of developing early-onset myopia in children, according to a recent Singapore study.
Mild respiratory depression common after epidural morphine for C-section
19 May 2019
Mild respiratory depression appears to be common in women given epidural morphine after caesarean delivery, a new study suggests.
Direct IUD insertion less painful than conventional technique
Tristan Manalac, 18 May 2019
A direct technique reduces the pain of intrauterine device (IUD) insertion as compared with the conventional technique, according to a new France study.
Metformin protects over 15 years: Time for diabetes prevention indication?
Pearl Toh, 17 May 2019
Metformin continues to protect high-risk individuals from developing type 2 diabetes (T2D) over 15 years, especially among those with higher glycaemic status at baseline and women reporting a history of gestational diabetes mellitus (GDM), according to long-term results from DPP/DPPOS*.
Norepinephrine more potent than phenylephrine for hypotension during C-section
16 May 2019
Norepinephrine is a more potent choice than phenylephrine for postspinal hypotension during elective caesarean section, a recent study has found.
Accelerated weight gain before childbearing may lead to gestational diabetes
14 May 2019
Excessive gains in overall and central fat prior to the childbearing period pose an increased risk of developing gestational diabetes mellitus, a study has found.
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Special Reports
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Gangliosides and cognition: An appraisal of the evidence
01 Sep 2018

Gangliosides and docosahexaenoic acid (DHA) play critical roles in early childhood brain development. 
Immunization protects children from vaccine-preventable diseases
21 Mar 2018
During the Kuala Lumpur International Neonatology Conference held in conjunction with the World Prematurity Day 2017, Dato Dr Musa Mohd Nordin spoke on the importance of immunizing children with the diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine. He highlighted the role of Hexaxim® as a fully liquid, ready-to-use, 6-in-1 (including hepatitis B) vaccine for the primary and booster vaccinations of infants and toddlers. Meanwhile, Dr Yong Junina Fadzil discussed the benefits of quadrivalent influenza vaccines (QIVs) in providing children with broader protection against influenza B viruses.
The role of goat milk in childhood nutrition
21 Mar 2018
Dr Elizabeth Carpenter, Principal Scientist of Dairy Goat Co-operative (DGC) in New Zealand, spoke to MIMS about goat milk as a source of protein in childhood nutrition. Below are highlights from the interview.
Bye-bye vaginal infection, hello vaginal flora!
22 Jan 2018
The human body is home to an estimated 100 trillion microbial cells and a quadrillion viruses, which are collectively known as the human microbiota. Recently, the human microbiota has gained the attention of the scientific fraternity for its roles in health and diseases, with some quarters referring to it as the 'forgotten organ'. Imbalances in the usual composition of commensal or symbiotic species in a localized area of the body is known as microbial shift or dysbiosis, and this condition may result in infections caused by opportunistic pathogens, thereby impacting the natural defence mechanism of the human body.
SNPs likely to improve breast cancer risk prediction
Dr Joslyn Ngu, 04 Dec 2017

Incorporating polygenic risk scores based on 18 SNPs (single nucleotide polymorphisms) into risk stratification for breast cancer will improve screening results, says an expert.
Integrating genetic testing into routine oncology care in the UK
Dr Joslyn Ngu, 04 Dec 2017

Making genetic testing mainstream, allows more patients to be tested, identifies more carriers and enables appropriate stratification of treatment and outcomes, says an expert.
Clinical genetic testing in HBOC syndrome
Dr Joslyn Ngu, 04 Dec 2017

Hereditary breast and ovarian cancer (HBOC) syndrome, which is primarily caused by BRCA1 and BRCA2 mutations, make up 8 to 10 percent of all breast cancers, says a senior consultant.
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Conference Reports
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Mastectomy tied to poor QoL in young women with breast cancer
Elaine Soliven, 10 Jan 2019
Younger women with breast cancer who had a mastectomy demonstrated a worse quality of life (QoL) compared with those who underwent breast-conserving surgery (BCS), according to a study presented at SABCS 2018.
Metabolic syndrome may affect survival outcomes in early breast cancer
Roshini Claire Anthony, 09 Jan 2019

Women with metabolic syndrome who are diagnosed with early breast cancer may have poorer survival outcomes, according to a study from Italy presented as a poster at SABCS 2018.
Scalp cooling device effective in reducing chemo-induced alopecia in breast cancer patients
Audrey Abella, 28 Dec 2018
Use of a scalp cooling device is effective in reducing alopecia or hair loss in patients with breast cancer who are undergoing neoadjuvant/adjuvant chemotherapy including anthracyclines* and taxanes**, according to studies presented at SABCS 2018.
High medication nonadherence rate, elevated CVD risk after breast cancer diagnosis
Roshini Claire Anthony, 27 Dec 2018

Women diagnosed with nonmetastatic breast cancer who were adherent to cardiovascular disease (CVD) medications pre-diagnosis had a high risk of becoming nonadherent post-cancer treatment, with nonadherence increasing their risk of CV events, according to a poster presented at the recent San Antonio Breast Cancer Symposium (SABCS 2018).

Lifestyle intervention tied to weight loss, better DFS in breast cancer
Elaine Soliven, 27 Dec 2018
A lifestyle intervention programme focusing on healthy habits was associated with weight loss and better disease-free survival (DFS) among early breast cancer survivors, according to the SUCCESS C* study presented at SABCS 2018.
Oxybutynin shows promise for hot flushes in women with breast cancer
Pearl Toh, 24 Dec 2018
The anticholinergic agent oxybutynin significantly reduces the intensity and frequency of hot flushes among women in whom hormone replacement therapy was contraindicated such as breast cancer survivors, according to the ACCRU study SC-1603 presented at SABCS 2018.
Exercise during breast cancer treatment helps preserve CV function
Pearl Toh, 19 Dec 2018
A structured cardiovascular (CV) exercise programme during adjuvant breast cancer treatment provides significant protection against decline in CV function related to chemotherapy-induced cardiotoxicity, according to the EBBA*-II trial presented at SABCS 2018, indicating that physical activity during treatment for breast cancer can benefit patients.
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Multimedia
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Podcast: Dr Leong Hoe Nam talks about the importance of maternal vaccination both for the mother and the child
Podcast: Assistant Professor David Tan highlights updates in ovarian cancer screening
Podcast: Dr Fen Lee Hew talks about the pressing need to prevent osteoporotic fractures in Asia
Podcast: Dr Joon Kiong Lee discusses pharmacotherapy for osteoporosis and the role of FLS in fracture prevention
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