Obesity is having an excessive amount of body fat in relation to lean body mass that may impair health.
The primary cause is an energy imbalance between calories consumed and expended.
Treatment goals include to lose 5-10% of body weight or 0.5-1 kg (1-2 lb)/week for 6 months and regain of <3 kg in 2 years and sustained reduction of waist circumference of at least 4 cm.
Strategies are aiming for realistic goals and a multidisciplinary approach that is a combination of dietary change, physical activity and behavioral modification.
The combination of maternal pregestational diabetes mellitus plus severe obesity is associated with a heightened risk of several psychiatric and mild neurodevelopmental disorders in offspring compared with either obesity or diabetes alone, a study suggests.
A postnatal lifestyle intervention programme (PAIGE) for overweight women with previous gestational diabetes mellitus (GDM) leads to significantly greater weight loss compared with usual care at 6 months, a recent study has shown.
Elevations in inflammatory protein levels in neonatal blood are associated with obesity among 2-year-old children born extremely premature, a study reports. This suggests that systemic inflammation contributes to the development of obesity.
Mothers who adhere to a healthy lifestyle during their offspring’s childhood and adolescence appear to substantially lower the risk of obesity in their children, suggests a recent study. Of note, observing a healthy lifestyle in both mothers and their children leads to an even lower risk of offspring obesity.
A nasal device that reduces the ability to smell can lead to weight loss and changes in dietary preference for sweet stuff in adults younger than 50 years with obesity, suggesting a novel approach to managing obesity, according to a pilot study presented at the recent European Congress on Obesity (ECO) in Vienna, Austria.
A recent study shows that poor sleep quality may lead to junk food cravings, which when adjusted for covariates correlate with an elevated risk of obesity, diabetes and other health problems. In addition, night-time snacking is associated with increased risk of diabetes.
Individuals with obesity but without diabetes experienced significant weight reduction with daily doses of the glucagon-like peptide-1 receptor agonist semaglutide, according to a recent study presented at ENDO 2018.
Individuals with severe obesity who undergo Roux-en-Y gastric bypass (RYGB) may have a higher risk of nonvertebral fractures than those who undergo adjustable gastric banding (AGB), according to a study presented at the recent ENDO 2018 sessions.