Obesity is having an excessive amount of body fat in relation to lean body mass that may impair health.
The primary cause is an energy imbalance between calories consumed and expended.
Treatment goals include to lose 5-10% of body weight or 0.5-1 kg (1-2 lb)/week for 6 months and regain of <3 kg in 2 years and sustained reduction of waist circumference of at least 4 cm.
Strategies are aiming for realistic goals and a multidisciplinary approach that is a combination of dietary change, physical activity and behavioral modification.
Overweight or obese patients taking lorcaserin as an appetite suppressant may have the added benefit of a reduced risk of incident diabetes, according to results of the CAMELLIA-TIMI 61* trial presented at EASD 2018.
Clinically severe obese individuals may be prone to nutritional deficiencies, with a large number having suboptimal vitamin D levels, according to a study from Singapore. The deficiencies may also differ by ethnicity.
Not only are probiotics healthy for the gut, they may also be good for the waistline. A recent study shows that supplementation with the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 (Ba8145) improves anthropometric adiposity measures such as waist circumference, body mass index (BMI), and visceral fat area in abdominally obese individuals, particularly in women.
Individuals with asthma may have a tendency to develop obesity, with a higher risk observed among those with adult-onset asthma, according to findings of the European Community Respiratory Health Survey (ECRHS) presented at the recent international congress of the European Respiratory Society (ERS 2018).
It appears that undesirable eating behaviour (EB) traits play a part in mediating genetic susceptibility to obesity, according to a recent study, suggesting that EB traits can be targeted in obesity treatment and prevention.
The combination of maternal pregestational diabetes mellitus plus severe obesity is associated with a heightened risk of several psychiatric and mild neurodevelopmental disorders in offspring compared with either obesity or diabetes alone, a study suggests.
A postnatal lifestyle intervention programme (PAIGE) for overweight women with previous gestational diabetes mellitus (GDM) leads to significantly greater weight loss compared with usual care at 6 months, a recent study has shown.
Elevations in inflammatory protein levels in neonatal blood are associated with obesity among 2-year-old children born extremely premature, a study reports. This suggests that systemic inflammation contributes to the development of obesity.
Mothers who adhere to a healthy lifestyle during their offspring’s childhood and adolescence appear to substantially lower the risk of obesity in their children, suggests a recent study. Of note, observing a healthy lifestyle in both mothers and their children leads to an even lower risk of offspring obesity.
The investigational oral synthetic androgen dimethandrolone undecanoate (DMAU) suppresses serum testosterone levels to near castrate levels and appears safe when taken once daily for a month, showing potential as a male contraceptive pill, according to a study.
In the context of low-glycaemic index (GI) dietary patterns, eating pasta does not contribute to adiposity and may even reduce body weight and body mass index (BMI) compared with higher-GI dietary patterns, a recent study has found.