nonalcoholic%20fatty%20liver%20disease
NONALCOHOLIC FATTY LIVER DISEASE

Nonalcoholic fatty liver disease is having excessive hepatic fat (in the form of triglycerides) accumulation not due to excessive alcohol consumption or other secondary causes.

It is considered as a hepatic manifestation of metabolic syndrome.

Progression of nonalcoholic fatty liver disease is variable.

Surgical Intervention

Bariatric Surgery
  • Alternative therapy in patients unresponsive to lifestyle changes and pharmacological therapy to reduce weight and metabolic complications as it has long-term stable results
  • It was shown in the surrogate markers that bariatric surgery is effective on NAFLD-associated liver injury and there is also initial evidence for improved necroinflammation and fibrosis
  • It is advised that surgery should be done before the patient becomes cirrhotic
Liver Transplantation
  • Accepted procedure in NASH patients with end-stage liver disease
  • It was found that overall survival after transplantation is approximately identical with patients who received liver transplants for hepatic failure caused by other liver diseases
  • Comorbid conditions limit eligibility for transplantation
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
21 Jun 2020
Extra-virgin olive oil reduces inflammatory markers and improves symptoms in patients with ulcerative colitis, a recent study has found.
09 Dec 2018
Supplementation with probiotics containing the combined LA-5, BB-12 and LC-01 strains does not effectively prevent antibiotic-associated diarrhoea in hospitalized patients, a study has shown.
Tristan Manalac, 11 Aug 2018
Consumption of whole-cricket powder appears to promote the growth of the probiotic gut bacterium Bifidobacterium animalis and reduce plasma concentrations of tumour necrosis factor-α, according to a recent trial.