Microbial therapies, such as prebiotics and probiotics, show potential in patients with nonalcoholic fatty liver disease, yielding reductions in body mass index, hepatic enzymes, serum cholesterol and triglycerides, a study has shown.
Coeliac disease patients have a threefold risk of nonalcoholic fatty liver disease (NAFLD) despite adherence to a gluten-free diet, a study has found. This risk is especially higher in the lean population.
Supplementation with omega-3 long-chain polyunsaturated fatty acids appears beneficial to patients with nonalcoholic fatty liver disease (NAFLD), producing significant improvements in liver fat content, steatosis score and several cardiometabolic risk factors, according to a systematic review and meta-analysis.
In Asian patients with nonalcoholic fatty liver disease, more severe liver disease is associated with factors such as older age, obesity, diabetes, dyslipidaemia, higher alanine transaminase and aspartate transaminase levels, and lower platelet count, according to a team of investigators.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.