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NONALCOHOLIC FATTY LIVER DISEASE

Nonalcoholic fatty liver disease is having excessive hepatic fat (in the form of triglycerides) accumulation not due to excessive alcohol consumption or other secondary causes.

It is considered as a hepatic manifestation of metabolic syndrome.

Progression of nonalcoholic fatty liver disease is variable.

Follow Up

  • Patient’s follow-up schedule may vary depending on local protocol, patient’s response and risk factors
  • After 6 months, evaluate weight loss, exercise, diet and lifestyle changes
  • Twice annually the following tests should be done:
    • Blood test with platelet count
    • Liver biochemical tests
    • Prothrombin time
  • Depending on risk factors present, do the following every 1-2 years:
    • Screen for cardiovascular risk
    • Liver biopsy
  • Imaging tests can only be done when indicated
  • Screen patients with NASH cirrhosis for gastroesophageal varices 
  • Screen NAFLD patients with suspected cirrhosis for hepatocellular carcinoma
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Dr. Joseph Delano Fule Robles, 18 Apr 2019

A recent study by investigators from Hong Kong showed that poor sleep quality and longer sleep onset latency are associated with an increased risk of peptic ulcer disease (PUD) recurrence. Depression is also shown to be associated with subsequent incidence of PUD.