Adding cilostazol to other antiplatelet agents could potentially reduce in-stent restenosis (ISR) among patients with carotid artery stenosis who undergo carotid artery stenting (CAS), according to results of the CAS-CARE* trial presented at ISC 2020.
outperformed warfarin in preventing ischaemic events regardless of prior stroke,
transient ischaemic attack (TIA), or thromboembolic event (TE) in patients with
atrial fibrillation (AF) with recent acute coronary syndrome (ACS) or percutaneous
coronary intervention (PCI), a
prespecified secondary analysis of the AUGUSTUS trial has shown.
Prompt treatment with tranexamic acid may reduce intracerebral haemorrhage (ICH) growth in patients with ongoing bleeding, though the timing of treatment appears to be key to improved outcomes, according to a study presented at ISC 2020.
The lower 0.25 mg/kg dose of the thrombolytic tenecteplase may be sufficient for reperfusion of blocked vessels prior to thrombectomy in patients with ischaemic stroke due to large-vessel occlusion compared with the 0.4 mg/kg dose, according to the EXTEND-IA TNK* Part 2 study presented at the ISC 2020 Meeting.
Having sufficient and healthy sleep, in addition to adopting healthy lifestyle based on the AHA* Life’s Simple 7 (LS7) guidelines, can reduce the risk of cardiovascular diseases (CVD), according to the longitudinal MESA** Sleep Study presented at EPI Lifestyle 2020 Scientific Sessions.
Skipping intravenous (IV) tissue plasminogen activator (tPA) before mechanical thrombectomy (MT) may have similarly favourable outcomes to using tPA pre-MT in patients with acute stroke, according to the SKIP* study presented at ISC 2020.
Home blood pressure telemonitoring (HBPTM) combined with telephone-based nurse case management (NCM) led to a greater reduction in systolic blood pressure (BP) among minority stroke survivors with uncontrolled hypertension than HBPTM alone, according to a study presented at ISC 2020.
Long‐term treatment with perampanel in the adjunctive setting appears to provide improved seizure control without raising new safety/tolerability signals in patients with epilepsy, particularly those with secondarily generalized seizures at baseline, according to the results of an open-label extension of phase III trials.
High rather than low levels of neonatal 25(OH)D3 pose an increased risk of incident epilepsy in early childhood, a finding that may be attributed to chance, confounding, or late gestational vitamin D exposure, according to a study.
In the treatment of idiopathic generalized epilepsy, switching from valproate to other antiepileptic drugs due to potential childbearing issues may prove detrimental, heightening the risk of poor seizure control, as shown in a recent study.