Outcomes after stroke thrombectomy were no better with tissue plasminogen activator (tPA) withheld in the MR CLEAN-NO IV trial, suggesting that the practice of giving thrombolytics still holds in stroke.
NEURoaid II (MLC901), a traditional Chinese medicine-based neuroprotective intervention under investigation, is safe to administer in patients with vascular cognitive impairment no dementia (VCIND), but does not seem to grant significant cognitive benefits, according to a recent Singapore study.
Select stroke patients who present late to the hospital — beyond 6 hours and up to 24 hours after stroke onset — still stand to benefit from endovascular thrombectomy, confirms the AURORA meta-analysis of six randomized trials presented at the ISC 2021 Meeting.
Getting patients with suspected large-vessel occlusion (LVO) stroke to undergo immediate angiography instead of the standard CT scan speeds up time stroke treatment and improves 90-day functional outcomes, according to the ANGIOCAT study presented at the ISC 2021 Meeting.
Among atrial fibrillation (AF) patients treated with nonvitamin K antagonist oral anticoagulants (NOACs) for stroke prevention, several parameters predict intracerebral haemorrhage (ICH), including older age, concurrent use of antiplatelet drugs, and hyperlipidaemia, among others, but not HAS-BLED and CHA2DS2-VASc scores, a study has found.