Children and young adults with congenital heart disease (CHD), particularly nonconotruncal defects and coarctation of the aorta, are about eight times as likely as those in the general population to develop haemorrhagic stroke, although the absolute risk appears to be low, according to a study.
Adolescents appear to have disordered normal brain growth trajectories after initiating drinking, with or without co-use of marijuana, a recent study has found. Peak consumption in the past year and family history of alcoholism possibly contribute to abnormal cortical volume trajectories.
Personality and subclinical behavioural changes, which begin during the transition from preclinical Alzheimer’s disease (AD) to mild cognitive impairment, resemble behavioural changes that manifest in patients with frank dementia, a recent study has shown.
Email reminders, provider education, signages and electronic medical record (EMR) best practice advisories (BPA) seem to be effective in improving folic acid supplementation rate in adolescent females with epilepsy, a recent study has shown.
Anterior temporal lobectomy appears to be more effective than the minimally invasive stereotactic radiosurgery in terms of inducing seizure remission in patients with pharmacoresistant unilateral mesial temporal lobe epilepsy, according to the results of the ROSE trial.
Long‐term treatment with perampanel in the adjunctive setting appears to provide improved seizure control without raising new safety/tolerability signals in patients with epilepsy, particularly those with secondarily generalized seizures at baseline, according to the results of an open-label extension of phase III trials.
Although the conversion rate of ocular (OMG) to generalized (GMG) myasthenia gravis in Asian patients is low, thymoma and acetylcholine receptor (AchR) antibodies as well as positivity in repetitive nerve stimulation (RNS) studies all predict such generalization, a recent Singapore study has shown.