Deep brain stimulation (DBS) of the ventral anterior limb of the internal capsule (vALIC) is well tolerated and effective for patients with treatment-refractory obsessive-compulsive disorder (OCD), a recent study has shown.
The anticonvulsant drugs levetiracetam, fosphenytoin and valproate all demonstrate efficacy for benzodiazepine-refractory convulsive status epilepticus, with each drug inducing seizure cessation and improving alertness in most patients and yielding similar safety outcomes, according to data from the Established Status Epilepticus Treatment Trial (ESETT).
In the treatment of paediatric patients with postdural puncture headache refractory to conservative therapies, the use of cosyntropin results in rapid pain relief, according to data from a retrospective analysis.
Prior intake of direct oral anticoagulants (DOACs) bears no increased risk of symptomatic intracerebral haemorrhage in acute ischaemic stroke patients initiating treatment with intravenous thrombolysis (IVT), according to the results of a meta-analysis.
Neonates undergoing continuous electroencephalography (cEEG) for a neurologic injury have an elevated risk of seizure initially, according to a study. Seizure risk over time may be predicted by EEG monitoring indication and early epileptiform charges.
Stimulation of a spicy sensation confers analgesic benefit that persists after the taste stimulation ends, a study has found. However, eating spicy diet in the long term may hurt the basal pain sensitivity.
Adults who developed multiple sclerosis (MS) in childhood or adolescence had significantly higher odds of impairment and greater decline over time in information-processing efficiency than adults who developed MS later in life, independent of age or disease duration, a large population-based longitudinal cohort study has shown.