Thyroid dysfunction during pregnancy is associated with several neurocognitive outcomes in the offspring, suggest the results of a study. Prompt examination and treatment on thyroid function is urged for pregnant women.
Use of eslicarbazepine acetate over the long term in the treatment of patients with focal epilepsy appears to be well tolerated and induces freedom from seizures, according to the results of an open-label study.
Spicy stimulation appears to trigger an analgesic effect that lasts beyond the taste stimulus, a recent study has found. In contrast, keeping a long-term spicy diet may instead lower the threshold for basal pain sensitivity.
In the treatment of schizophrenia, patients on typical antipsychotics have better memory than those taking clozapine or risperidone, and patients on clozapine have better language function compared with those on risperidone, as shown in a study.
Tirofiban as an adjunct to endovascular thrombectomy in acute ischaemic stroke patients may be beneficial or detrimental depending on the route of administration, such that intravenous treatment leads to high recanalization rate and good outcome, whereas the intra-arterial route is associated with increased bleeding and mortality, according to a study.
An integrated telerehabilitation approach (ITA) confers benefits to individuals with multiple sclerosis (MS) in the treatment of motor symptoms according to the current model of continuity of care, reports a recent study.
The centrally penetrant, selective serotonin 1F (5‐HT1F) receptor agonist lasmiditan appears to adversely affect driving performance at 1.5 hours postdose, but this effect disappears after 8 hours, as shown in a crossover trial.
Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.
Use of systemic corticosteroids does not reduce in-hospital mortality for patients with severe or critical coronavirus disease (COVID-19), which is in stark contrast to that observed in the RECOVERY clinical trial, according to a study in Wuhan, China.