The treatment window for endovascular thrombectomy has been extended from 6 to 24 hours within the onset of a stroke in the new stroke guidelines, expanding the number of patients eligible for thrombectomy. However, experts said this does not mean time no longer matters in thrombectomy.
Despite guidelines advocating stroke risk factor assessment following retinal infarction (stroke of the eye), adherence to the guidelines within 90 days of infarct was poor among elderly patients, leading to a potentially elevated risk of stroke, according to a study presented at the recent International Stroke Conference 2018 (ISC 2018) in Los Angeles, California, US.
The use of a ticagrelor/aspirin combination was more successful than a clopidogrel/aspirin combination in reducing the rate of high on-treatment platelet reactivity (HOPR) in patients with a recent minor stroke or transient ischaemic attack (TIA), according to results of the PRINCE* trial conducted in China.
Combining the anticoagulant rivaroxaban with aspirin reduces the risk of ischaemic stroke by almost half without a significant increase in the risk of intracerebral haemorrhage (ICH) or haemorrhagic transformation compared with aspirin alone in patients with stable coronary artery disease (CAD), according to new data from the COMPASS* study presented at ISC 2018.
The use of tenecteplase may be a suitable alternative to alteplase prior to endovascular thrombectomy in patients with a large vessel ischaemic stroke, according to results of the EXTEND-IA TNK* study.
A combination of the cholesterol-lowering drug rosuvastatin and blood pressure-lowering drugs candesartan and hydrochlorothiazide led to a significant 44 percent reduction in the risk of first strokes among individuals with an intermediate risk of cardiovascular (CV) disease, results from the HOPE-3* study showed.
Presence of fluid sacs in the kidneys may be indicative of an increased risk of stroke, suggest preliminary data from a study presented at the International Stroke Conference (ISC) 2018 in Los Angeles, California, US.
Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.
Use of systemic corticosteroids does not reduce in-hospital mortality for patients with severe or critical coronavirus disease (COVID-19), which is in stark contrast to that observed in the RECOVERY clinical trial, according to a study in Wuhan, China.