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Neurology
Top Medical News
Epstein-Barr virus (EBV) may be the first trigger for the development of multiple sclerosis (MS) in most cases, says an expert.
Among patients with epilepsy, quality of life (QOL) declines with antiseizure medication (ASM) polytherapy, and this effect is mediated by depression and the side effects of ASMs, as reported in a study.
People who consume more olive oil in their diet have a lower risk of death from any cause or specific causes including cardiovascular disease (CVD), cancer, neurodegenerative disease, or respiratory disease compared with those who hardly or never consume olive oil, according to a large US study.
Among menopausal women, severe depression and sexual dysfunction appear to have a negative impact on cognitive performance, as suggested in a study.
Young-onset dementia (YOD), particularly the Alzheimer’s type, occurs with high frequency among Southeast Asians, according to data from a memory clinic cohort in Singapore. Furthermore, YOD patients with higher education and those who have late-onset dementia with moderate-to-severe cerebrovascular disease burden exhibit a steeper and faster decline in global cognition.
A significant presence of psychosis exists among patients with Parkinson’s disease (PD) in Singapore, potentially indicating a more rapid cognitive decline and progression of PD severity, reports a study.
Existing scoring systems for magnetic resonance imaging (MRI) scans are sufficiently predictive of cognitive and motor outcomes in term-born infants, a recent study has found. For language assessment, more detailed scoring inventories seem to perform better.
Special Reports
Multiple sclerosis (MS) is one of the most common neurological disorders – affecting over 2.3 million people globally – and it is the leading cause of nontraumatic disability in young adults. However,the availability of supportive resources and services for people with MS is scarce in many regions of the world. In Malaysia, the prevalence of MS is estimated at 2-3/100,000; the current Malaysian clinical practice guidelines on the management of MS recommend disease modifying agents, such as interferon-β and teriflunomide, as first-line therapeutic agents. In this article, Dr Singer - in partnership with Sanofi and the Malaysian Society of Neurosciences - shares his insights into managing MS dynamically, highlighting the importance of early intervention in improving patient outcomes.
Conference Reports
Several studies presented at AAIC 2021 have suggested a possible link between COVID-19 and cognitive impairment.
Treatment with high-dose aducanumab shows less clinical decline across individual items or domains of cognition, function, and behaviour compared with placebo in patients with early symptomatic Alzheimer’s disease (AD), according to the EMERGE* study presented at AAIC 2021.
Transgender adults had a higher likelihood of experiencing subjective cognitive decline (SCD) and SCD-related functional limitations compared with their cisgender counterparts, according to a study presented at AAIC 2021.
Midlife adults aged between 50 and 70 years who reported a short sleep duration of ≤6 hours/night had an increased risk of developing dementia later in life, according to a study presented at AAIC 2021.
Two studies presented at AAIC 2021 showed a potential neuroprotective effect of a ketogenic supplement or diet: In one study, consumption of a keto drink was associated with improvements in dorsal attention network (DAN) functional connectivity in mild cognitive impairment (MCI). Another study showed the keto diet’s potential to improve aberrant default mode network (DMN) connectivity patterns in adults at risk for Alzheimer’s disease (AD).
Improved air quality was associated with a slower cognitive decline and a lower risk of developing dementia, according to studies presented at AAIC 2021.
A new systematic review and meta-analysis presented at AAIC 2021 has hinted at a high prevalence of young-onset dementia (YOD) worldwide.