Neurology

DAPT with cilostazol reduces stroke recurrence without raising bleeding risk

an hour ago

Dual antiplatelet therapy (DAPT) using cilostazol appears to be more beneficial than single antiplatelet therapy, with the results of a study suggesting that DAPT helps lower the incidence of ischemic stroke recurrence without increasing the risk of severe or life-threatening bleeding.

Modified Atkins diet may be better than keto for childhood drug-resistant epilepsy

Yesterday

Dietary modifications offer short-term benefits in children with drug-resistant epilepsy, but modified Atkins diet appears more tolerable and more likely to reduce the frequency of seizures than ketogenic diet, as shown in a study.

Papilledema widely misused in medical literature

2 days ago

The term ‘papilledema’ is often used inappropriately among case reports in ophthalmology, reveals a recent study. Such misuse, if not corrected, can result in improper care delivery to patients with optic disc edema (ODE), which may then lead to permanent vision loss.

Antipsychotic prescriptions for dementia soared during COVID-19 pandemic

Kanas Chan, 5 days ago

The overall rate of antipsychotic drug prescriptions to patients with dementia increased markedly during the initial months of the COVID-19 pandemic, and did not return to prepandemic levels when the acute phase was over, a multinational network cohort study has shown.

Screen time may affect brain development in early childhood

Audrey Abella, 30 Jan 2023

In preschool-aged children, higher digital media use (screen time) was associated with lower cortical thickness (CT) and sulcal depth (SD), according to a secondary analysis of data collated for an MRI-based study.

Physical activity helps prevent dementia, cognitive impairment in women

Jairia Dela Cruz, 30 Jan 2023

Walking daily and performing moderate-to-vigorous physical activity can help lower the risk of mild cognitive impairment (MCI) or dementia in ageing women, as shown in a study.

Shifting paradigms in MS management: Early, optimized interventions improve patient outcomes

04 May 2018

Multiple sclerosis (MS) is one of the most common neurological disorders – affecting over 2.3 million people globally – and it is the leading cause of nontraumatic disability in young adults. However,the availability of supportive resources and services for people with MS is scarce in many regions of the world. In Malaysia, the prevalence of MS is estimated at 2-3/100,000; the current Malaysian clinical practice guidelines on the management of MS recommend disease modifying agents, such as interferon-β and teriflunomide, as first-line therapeutic agents. In this article, Dr Singer - in partnership with Sanofi and the Malaysian Society of Neurosciences - shares his insights into managing MS dynamically, highlighting the importance of early intervention in improving patient outcomes.

Sovateltide: A new option to improve neuro outcomes after cerebral ischaemic stroke?

Roshini Claire Anthony, 26 Dec 2022

The endothelin-B receptor agonist sovateltide appears to improve neurological outcomes in patients with acute cerebral ischaemic stroke (ACIS), according to a phase III trial presented at WSC 2022.

CT angiography may increase potential recipients of EVT for acute ischaemic stroke

CT angiography may increase potential EVT recipients for acute ischaemic stroke

Roshini Claire Anthony, 27 Nov 2022

Using collateral flow findings, as seen on computed tomographic (CT) angiography, may widen the population who can undergo late endovascular treatment (EVT) for acute ischaemic stroke (AIS), according to findings of the MR CLEAN-LATE trial.

Intensive BP-lowering a no-go after reperfusion in ischaemic stroke

Roshini Claire Anthony, 14 Nov 2022

An intensive blood pressure target (<120 mm Hg) should be avoided in patients who have undergone endovascular thrombectomy for acute ischaemic stroke (AIS) for large-vessel occlusion (LVO), results of the phase III ENCHANTED2/MT* trial showed.

Higher ultra-processed food intake tied to faster cognitive decline

Elaine Soliven, 14 Sep 2022

High consumption of ultra-processed food (UPF) appears to be associated with a rapid decline in cognitive function in adults, according to the ELSA-Brasil* study presented at AAIC 2022.

Hypertensive disorders of pregnancy: A risk factor for dementia?

Roshini Claire Anthony, 05 Sep 2022

Individuals with a history of hypertensive disorders of pregnancy (HDP) appear to have an increased risk of developing dementia, particularly vascular dementia, according to a study presented at AAIC 2022.

ICU admission tied to dementia risk

Roshini Claire Anthony, 30 Aug 2022

Older adults who have been admitted to the intensive care unit (ICU) may have an elevated risk of developing Alzheimer’s dementia or all types of dementia, according to a study presented at AAIC 2022.

Brexpiprazole shows promise in reducing agitation due to Alzheimer’s dementia

Elaine Soliven, 26 Aug 2022

Treatment with brexpiprazole at either 2 or 3 mg significantly reduced agitation compared with placebo in patients with Alzheimer’s dementia, according to the Trial 331-14-213* presented at AAIC 2022.