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Top Medical News
Surgery for glioma appears to improve complex attention, memory, learning and language, according to a recent Singapore meta-analysis. On the other hand, the procedure seems to result in a slight decline in executive function.
Persistent pulmonary hypertension of the newborn occurs more frequently in Asian than in western settings, according to a study. Risk factors implicated in mortality include prematurity, congenital diaphragmatic hernia/lung hypoplasia, high frequency oscillation ventilation and inotropic agents.
The anti-PD-1 immunotherapy pembrolizumab confers survival benefit over standard chemotherapy in patients with recurrent or metastatic head and neck cancer in the first-line setting, reveals the topline results of the KEYNOTE-048* study presented at ESMO 2018.
People who expect to feel intense pain often do, even when the stimulus, in reality, is not particularly painful, according to a recent study.
Catching a common infection during stroke hospitalization appears to contribute to an increased risk of being readmitted, a study has found.
Higher exposure to ticagrelor following myocardial infarction does not appear to contribute to an increased risk of intracranial haemorrhage, which is associated with age and prior cardiovascular morbidities, according to a study.
Individuals who smoke and consume alcohol regularly during their mid-life years may have an elevated risk of cognitive impairment later in life, according to a Singapore study.
Special Reports
Multiple sclerosis (MS) is one of the most common neurological disorders – affecting over 2.3 million people globally – and it is the leading cause of nontraumatic disability in young adults. However,the availability of supportive resources and services for people with MS is scarce in many regions of the world. In Malaysia, the prevalence of MS is estimated at 2-3/100,000; the current Malaysian clinical practice guidelines on the management of MS recommend disease modifying agents, such as interferon-β and teriflunomide, as first-line therapeutic agents. In this article, Dr Singer - in partnership with Sanofi and the Malaysian Society of Neurosciences - shares his insights into managing MS dynamically, highlighting the importance of early intervention in improving patient outcomes.
CoQ10 isn't as popular as vitamin C or B in our daily lives but it's time to have a closer look at this vital nutrient.
At the Schwabe-Menarini lunch symposium of the 11th International Congress of the Asian Society AgainstDementia (ASAD) 2017 held in Bangkok, Thailand, Professor Ralf Ihl highlighted the role of standardized Gingko biloba extract EGb 761® for the treatment of patients with behavioural and psychological symptoms of dementia (BPSD). Meanwhile, Associate Professor Nagaendran Kandiah presented clinical findings on the association between cerebrovascular disease (CVD) and dementia, and emphasized the role of EGb 761® in the management of dementia with CVD.
At the recent launch of Nurofen® Express by Reckitt Benckiser Malaysia, Ms Joyce McSwan spoke on the importance of managing tension-type headache (TTH), highlighting the roles of drug and non-drug approaches in improving treatment outcomes.
Blood pressure lowering medications and statins do not prevent cognitive and functional decline in elderly patients, according to results of the HOPE-3 trial* presented at the Scientific Sessions of the American Heart Association (AHA 2016) held recently in New Orleans, Louisiana, US.
A 55-year-old man presented with almost one year history of heat intolerance, mild palpitation and significant weight loss. Free T3 and T4 were elevated with normal TSH. Patient had suboptimal response to carbimazole therapy.
Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.
Conference Reports
Changes in cardiometabolic factors such as body mass index (BMI), glucose levels, and blood pressure (BP) may signify dementia risk up to 14 years pre-diagnosis, with management of these risk factors potentially preventing dementia, according to a French population-based study presented at the Alzheimer’s Association International Conference (AAIC 2018).
Supervised aerobic-strength training improved cognitive and motor functions among elderly individuals with mild cognitive impairment (MCI), according to studies presented at AAIC 2018.
A new study reinforces the gut-brain connection in Alzheimer’s disease (AD), untangling the complex interplay between gut and brain health that could potentially lead to new therapies targeted at manipulating the gut microbiome to treat AD.
Incorporating virtual reality (VR) modules into the ‘Bringing Art to Life’ (BATL) service learning programme provided participants with a greater understanding of people with Alzheimer’s disease (AD) and other dementias (PWDs), according to a presentation at the Alzheimer’s Association International Conference (AAIC 2018).
The novel oral BACE* inhibitor elenbecestat showed an acceptable safety profile and was generally well tolerated in patients with mild cognitive impairment (MCI)-to-moderate Alzheimer’s disease (AD), with additional benefit of reducing amyloid load in the brain, a new study finds.
There is no evidence that hormone replacement therapy (HRT) may affect cognitive ability, especially when it is initiated early on during menopausal transition, according to studies presented at AAIC 2018, suggesting a need to rethink the long-held belief that HRT may negatively affect cognition.
The synthetic cannabinoid nabilone significantly improves noncognitive symptoms, in particular agitation, in people with moderate-to-severe Alzheimer's disease (AD), suggests a small randomized controlled trial.
