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Acceptance may improve quality of life, mental health following spinal cord injury

42 minutes ago

Acceptance is an important psychological resource that healthcare professionals can tap to improve quality of life (QoL) and mental health in individuals living with spinal cord injury (SCI), results of a recent systematic review suggest.

Trio of trials supports roxadustat for CKD-anaemia

Elvira Manzano, 21 hours ago

Roxadustat improves haemoglobin levels vs placebo and epoetin alfa, with similar safety profile, in 8,000 patients with chronic kidney disease (CKD)-related anaemia on- and off-dialysis, according to a pooled efficacy and CV safety analyses of roxadustat, spanning over 13,000 patient exposure years.

Men, women equally benefit from endovascular treatment for stroke

Jairia Dela Cruz, 5 days ago

Endovascular treatment for ischaemic stroke produces improvements in functional outcome and other clinical, imaging and safety outcome measures. The treatment effect is similar between men and women, with the latter even having more years of healthy life, as shown in the results of two recent studies.

Radiofrequency modalities hold promise in management of knee OA

12 Nov 2019

Radiofrequency ablation and neuromodulation modalities for knee osteoarthritis (OA) potentially improve pain, functionality and disease-specific quality of life for up to 3–12 months with minimal localized complications, according to the results of a systematic review.

Retrospective analysis supports off-label thrombectomy in childhood stroke

Natalia Reoutova, 12 Nov 2019

A retrospective, multicentre cohort study has shown that the safety profile of thrombectomy in childhood stroke does not differ from the safety profile in randomized clinical trials for adults, supporting clinicians’ off-label practice of thrombectomy in paediatric patients, in the absence of high-level evidence.

Shifting paradigms in MS management: Early, optimized interventions improve patient outcomes

04 May 2018

Multiple sclerosis (MS) is one of the most common neurological disorders – affecting over 2.3 million people globally – and it is the leading cause of nontraumatic disability in young adults. However,the availability of supportive resources and services for people with MS is scarce in many regions of the world. In Malaysia, the prevalence of MS is estimated at 2-3/100,000; the current Malaysian clinical practice guidelines on the management of MS recommend disease modifying agents, such as interferon-β and teriflunomide, as first-line therapeutic agents. In this article, Dr Singer - in partnership with Sanofi and the Malaysian Society of Neurosciences - shares his insights into managing MS dynamically, highlighting the importance of early intervention in improving patient outcomes.

Management of dementia beyond cognition – a deeper look into BPSD and CVD

13 Dec 2017

At the Schwabe-Menarini lunch symposium of the 11^th International Congress of the Asian Society AgainstDementia (ASAD) 2017 held in Bangkok, Thailand, Professor Ralf Ihl highlighted the role of standardized Gingko biloba extract EGb 761^®for the treatment of patients with behavioural and psychological symptoms of dementia (BPSD). Meanwhile, Associate Professor Nagaendran Kandiah presented clinical findings on the association between cerebrovascular disease (CVD) and dementia, and emphasized the role of EGb 761^®in the management of dementia with CVD.

Hypertension and cholesterol lowering interventions do not reduce cognitive decline

Roshini Claire Anthony, 22 Nov 2016

Blood pressure lowering medications and statins do not prevent cognitive and functional decline in elderly patients, according to results of the HOPE-3 trial* presented at the Scientific Sessions of the American Heart Association (AHA 2016) held recently in New Orleans, Louisiana, US.

Active lifestyle may delay Alzheimer’s disease progression

Roshini Claire Anthony, 13 Aug 2019

An active lifestyle, regardless of vascular risk, may delay the progression of Alzheimer’s disease (AD) by slowing down cognitive decline and neurodegeneration, according to a study presented at the Alzheimer’s Association International Conference (AAIC 2019).

LGBT, gender non-conforming population at greater risk for cognitive decline

Roshini Claire Anthony, 07 Aug 2019

Individuals who identify as sexual or gender minorities (SGM) appear to be at a higher risk of experiencing subjective cognitive decline (SCD) than individuals who identify as cisgender and heterosexual, according to a study presented at the Alzheimer’s Association International Conference (AAIC 2019).

Use of sleep meds may elevate dementia, Alzheimer’s risk

Roshini Claire Anthony, 05 Aug 2019

The use of sleep medications may be associated with the risk of dementia or Alzheimer’s disease (AD) in older adults, according to two studies presented at the recent Alzheimer’s Association International Conference (AAIC 2019).

Multisensory loss may up dementia risk

Audrey Abella, 01 Aug 2019

Multisensory dysfunction is tied to an increased risk of developing dementia or Alzheimer’s disease (AD) in older adults, thus underlining the importance of sensory evaluation in this patient subgroup and among those at risk of developing neurodegenerative illnesses, according to studies presented at AAIC 2019.

Identification of biomarkers one step closer towards blood testing for Alzheimer's

Pearl Toh, 31 Jul 2019

Biomarkers in the blood may present a new opportunity for developing a simple, noninvasive, and inexpensive screening test for Alzheimer’s disease (AD), according to studies presented at the Alzheimer's Association International Conference (AAIC) 2019.

Dementia, Alzheimer’s disease tied to seizure risk

Audrey Abella, 31 Jul 2019

The odds of experiencing seizures and epileptic seizure recurrence were higher among individuals with vs without dementia or Alzheimer’s disease (AD), according to data presented at AAIC 2019.

Men vs women: How the brains are wired differently

Pearl Toh, 26 Jul 2019

Sex-specific differences in the way brain regions are connected may influence how tau propagates through the brain and thus, differences in the risk of Alzheimer’s disease between men and women; while participating in the workforce may help stave cognitive decline in women, suggest studies presented at AAIC 2019.