Nausea%20-and-%20vomiting News

News

Chemo-induced nausea, vomiting? There’s a dexamethasone-free regimen for that

Jairia Dela Cruz, 20230828140000

A dexamethasone-free regimen helps improve control of nausea and vomiting in patients receiving “highly emetogenic” chemotherapy, with the antiemetic effect being superior to that of a dexamethasone-based regimen, according to the results of a phase III trial presented at ASCO Breakthrough 2023.

Fosaprepitant dosing frequency makes no difference in CCRT-induced nausea, vomiting prevention

Jairia Dela Cruz, 20230809140000

For patients undergoing concurrent chemoradiotherapy (CCRT), treatment with either weekly or every-3-weeks fosaprepitant helps reduce nausea and vomiting caused by CCRT, with no difference in the effect, as reported in a study.

NEPA- and olanzapine-based regimens similarly effective at preventing CINV in early BC

Sarah Cheung, 20230315080000

In a post hoc analysis of two prospective studies, netupitant/palonosetron (NEPA) combined with dexamethasone has demonstrated similar efficacy vs a quadruplet regimen of olanzapine, aprepitant, ondansetron, and dexamethasone in preventing chemotherapy-induced nausea and vomiting (CINV) in Chinese women with early breast cancer (BC) receiving doxorubicin/cyclophosphamide (AC) in Hong Kong.

Original New Drug Application Approvals by US FDA (16 - 30 Sep 2022)

20221006023651

New drug applications approved by US FDA as of 16-30 Sep 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Cannabis products ease nausea within 5 minutes

20220408130000

Patients who use cannabis to treat nausea normally experience relief within a relatively short period of time, a recent study has shown. However, the level of antiemetic effect varies with the characteristics of the cannabis products consumed in vivo.

Hypnotherapy, standard medical treatment equally effective at easing paediatric nausea symptoms

20211104080000

Gut-directed hypnotherapy appears to be as good as standard medical treatment in terms of reducing nausea symptoms in children with functional nausea or functional dyspepsia, according to a study.

Olanzapine a favourable alternative to dexamethasone for CINV

Audrey Abella, 20210927100000

Olanzapine administered at a dose of 5 mg was noninferior to dexamethasone and is associated with fewer adverse effects than dexamethasone for chemotherapy-induced nausea and vomiting (CINV), according to data presented at ESMO 2021.

Topiramate works for secondary prevention of cyclic vomiting syndrome with red flags

20210621080000

Topiramate appears to be an effective second-line prophylactic medication against moderate-to-severe cyclic vomiting syndrome in adults but at the cost of side effects, a study has shown.

Chlorpromazine–ketamine combo provides rapid relief of nausea, vomiting

20191007160000

Use of the combination of chlorpromazine plus ketamine leads to rapid, definitive cessation of symptoms in patients presenting with intractable nausea and vomiting, as shown in a recent study.

Long COVID: What we have learned so far

Prof. Ghassan Dbaibo, 27 Apr 2023

The WHO defines long COVID as a condition that occurs 3 months from COVID-19 onset, whose symptoms last ≥2 months and cannot be attributed to an alternative diagnosis. In an interview with MIMS Doctor, Professor Ghassan Dbaibo of the Center for Infectious Diseases, American University of Beirut, Beirut, Lebanon, describes the evolving attitudes towards long COVID among healthcare professionals (HCPs), some unexpected predisposing factors, potential biological mechanisms behind prolonged symptom duration and shares data on vaccination’s protective effects against long COVID.

Product Highlight - Ravida

13 Sep 2022

Ravidasvir 200 mg tab

Relationship between tumour response to systemic therapy and overall survival in unresectable hepatocellular carcinoma

Dr Raghav Sundar, 09 Sep 2019

Overall survival (OS) is currently the primary criteria in assessing the efficacy of a cancer treatment. Dr Raghav Sundar, a consultant medical oncologist at the National University Hospital, Singapore, details the crucial role played by tumour response in evaluating treatment efficacy, with a focus on the multiple kinase inhibitor lenvatinib in the treatment of hepatocellular carcinoma (HCC).