narcolepsy
NARCOLEPSY

Narcolepsy is a chronic neurologic sleep disorder wherein the patient have excessive daytime sleepiness and rapid eye movement sleep is dysregulated.

It affects 1 in 1000 individuals, with prevalence of about 0.04% of general population.
The exact cause remains unclear.
Studies suggest a combination of genetic predisposition, abnormal neurotransmitter functioning and abnormal immune modulation.
Symptoms include excessive daytime sleepiness, cataplexy, sleep paralysis, sleep-related hallucinations, automatic behavior, fragmented nocturnal sleep and insomnia.

Narcolepsy Drug Information

Drug Information

Indication: Attention deficit hyperactivity disorder (ADHD).

Indication: Depression including depression w/ associated anxiety. Generalized anxiety disorder (GAD) including long-term ...

Indication: Depressive illness, symptoms of depressive disorder & obsessive compulsive disorder (OCD).

Indication: Depression, obsessive-compulsive disorder, premenstrual dysphoric disorder (PMDD).

Indication: Symptomatic treatment of depression w/ or w/o anxiety. Obsessive compulsive disorder, pre-menstrual dysphoric ...

Indication: ADHD, narcolepsy.

Indication: Depression. Bulimia nervosa.

Indication: Major depressive disorder, panic disorder w/ or w/o agoraphobia, premenstrual dysphoric disorder, social anxie...

Indication: ADHD in childn ≥6 yr, adolescents & adults.

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Dr. Richard Shek-Kwan Chang, 11 Oct 2018
A 38-year-old right-handed man had had epilepsy since 2 months of age. There was no relevant family history. Perinatal history was unremarkable. No other risk factors such as central nervous system infection or cerebral trauma were identified. Developmental history did not show major delay. His epilepsy was uncontrolled despite trying valproate, carbamazepine, clobazam, levetiracetam, oxcarbamazepine and perampanel.