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MUMPS

Mumps is a self-limited viral disease characterized by nonsuppurative swelling and tenderness of one or both parotid glands.
It commonly affects the children aged 2-12 years and very uncommon in <1 year of age.
It is caused by a single-stranded RNA virus classified under Paramyxoviridae family or mumps virus.
Transmission is through airborne droplets from respiratory secretion of infected persons.
Incubation period is typically 14-21 days.

Mumps Management

Management

Prevention

Mumps Vaccine

Available as a single-antigen preparation or combined w/ other vaccines [eg mumps & rubella (MMR), or also w/ varicella (MMRV)]
- Single-antigen is not routinely recommended
- Based on several studies, a single dose of MMR is 75-91% effective while vaccine effectiveness of 88% is seen w/ 2 doses
- MMRV is approved for use in healthy children 1-12 yrs of age

Single-antigen (MMR) is indicated for children ≥1 yr of age w/ low risk for mumps exposure
Second-dose MMR is indicated for children 4-6 yr of age at high risk for mumps exposure
Second dose should be given >1 mth after the 1st dose

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Fetoscopic laser ablation improves survival in TTTS, requires highly skilled team

Stephen Padilla, 23 Nov 2020

Fetoscopic laser ablation (FLP) is an effective treatment for twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies, but it requires a tertiary neonatal facility and a highly specialized team in performing intervention therapies for the treatment of potential complications, according to a Singapore study.

Folate levels during pregnancy affect offspring neurodevelopment

18 Nov 2020

Serum folate levels during pregnancy correlate with the child’s neurodevelopment at 2 years of age, particularly in terms of language development, a recent study has shown. Folate supplementation may be a valuable nutritional intervention to consider.