The combination of panobinostat, dexamethasone, and subcutaneous (SC) bortezomib shows promising responses in patients with relapsed or relapsed and refractory multiple myeloma (RRMM), according to the phase II PANORAMA 3* study. Furthermore, SC bortezomib may be preferable to the intravenous (IV) option for reducing toxicity.
In Asian patients with dyslipidemia, statin intensity titration exerts favourable effects on low-density lipoprotein cholesterol (LDL-C) levels and goal attainment rates, although the magnitude appears to be lower than reports from clinical trials, according to a study.
Replacing a refined-grain snack with peanuts in the habitual diet does not significantly change glycaemic or lipid parameters but improves overall metabolic syndrome (MetS) risk without inducing weight gain among adults at high risk of cardiometabolic diseases, according to a China study.
A second-generation internal condom product, called the Woman’s Condom, is highly acceptable to users across the globe, a study has shown. Its special design features include easy insertion, secure fit during use, good sensation, and easy removal, as well as protection against pregnancy and sexually transmitted infections (STIs).
Chronic obstructive pulmonary disease (COPD) patients with chronic respiratory failure fare well with noninvasive home ventilation treatment, which cuts the risk of death and healthcare utilization, a study has found.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.