The addition of bevacizumab (BVZ) to the standard regimen for the treatment of advanced colorectal cancer (CRC) appears to increase the risk of cardiovascular events, suggest the results of a meta-analysis presented at the recent ASCO Gastrointestinal Cancers Symposium (ASCO GI 2023).
Hypofractionated radiotherapy (HFRT) is not superior to conventionally fractionated radiotherapy (CFRT) in providing survival benefits to patients with stage I nonsmall cell lung cancer (NSCLC), but HFRT is preferable due to its convenience and lower costs, according to a study.
Adding the anti-PD-1 monoclonal antibody tislelizumab to chemotherapy in the first-line treatment of PD-1-positive advanced gastric or gastroesophageal junction adenocarcinoma appears to produce significant and clinically meaningful improvements in survival outcomes while having an acceptable safety profile, according to interim data from the phase III RATIONALE 305 trial.
Treatment with the dual PPAR α/γ agonist saroglitazar helps improve the serum atherogenic lipoprotein profile in patients with nonalcoholic fatty liver disease (NAFLD), regardless of comorbid conditions and statin use, as shown in a study.
Epinephrine, given either at standard or high dose or in combination with vasopressin during out-of-hospital cardiac arrest (OHCA) resuscitation, leads to more favourable return of spontaneous circulation (ROSC) and survival to hospital admission but not survival to discharge or functional outcome, according to a study.
Antibiotic prophylaxis with vancomycin plus gentamicin alone for primary inflatable penile prosthesis surgery results in a higher risk of infection compared to nonstandard antibiotic regimens, suggests a recent study. On the other hand, antifungal use appears to reduce infection risk.
Treatment with single fraction radiation therapy (RT) results in lesser hepatic pain in most patients with end-stage hepatocellular carcinoma (HCC) or liver metastases, according to a study presented at the recent ASCO Gastrointestinal Cancers Symposium (ASCO GI 2023).
Men with urologic chronic pelvic pain syndrome (UCPPS) tend to suffer a more severe sexual dysfunction, including erectile (ED) and ejaculatory dysfunction, when compared to their healthy counterparts or patients with other chronic pain conditions, reveals a study.