Administering a high-dose oxytocin regimen for labour augmentation falls short of reducing caesarean births, although it produces a marked reduction in labour duration and chorioamnionitis frequency, without deleterious effects on perinatal outcomes as compared with standard dosing, according to a study.
Niraparib maintenance therapy improved progression-free survival (PFS) in patients with platinum-sensitive recurrent ovarian cancer (PSROC) regardless of time to progression since penultimate platinum chemotherapy or response to last chemotherapy, according to subgroup analyses of the NORA trial.
Low bone mineral density (BMD), on its own, is predictive of a heightened risk of atherosclerotic cardiovascular disease (ASCVD) in women, as well as provides an incremental prognostic value over age and other clinical risk factors, as shown in a study from Korea.
Electroacupuncture seems as effective and safe as prucalopride in relieving severe chronic constipation (SCC), a recent study has shown. Moreover, the effects of 8-week electroacupuncture persist for 24 weeks after treatment.
A web-based mobile application (app) called MyCOVIDRisk estimates the risk of COVID-19 transmission and has been found to be feasible and acceptable among the US public, a study has shown. Transmission risk can be estimated for app users, without collecting personal health data, based on local prevalence of disease, type of activity, and mitigation measures employed.
The combination of the immune checkpoint inhibitor atezolizumab and the angiogenesis inhibitor bevacizumab continues to demonstrate significant clinical benefits vs the oral multikinase inhibitor sorafenib in patients with unresectable hepatocellular carcinoma (HCC), according to updated results from the IMbrave150 trial.
The anti-PD-1 monoclonal antibody sintilimab outperformed docetaxel as second-line treatment for advanced and metastatic squamous non-small-cell lung cancer (NSCLC), according to the results of the phase III ORIENT-3 trial presented at AACR 2021.
Despite its big potential in boosting healthcare quality, artificial intelligence (AI) still seems immature to be clinically deployed against the novel coronavirus disease (COVID-19) pandemic, according to a recent Singapore systematic review.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.
The effect of cannabidiol (CBD) in the treatment of patients with Lennox–Gastaut syndrome may occur within 7 days of initiation, and most adverse events resolve within a 14-week period, a study reports.
In a webinar held on 27 March 2021, paediatric
endocrinology nurses Karen Blair,
Kate Davies, and Siti Zarina Yaakop shared
insights and clinical experience based
on their frontline roles in caring for patients
with central precocious puberty (CPP)
and supporting their family members.