A systematic review of randomized controlled trials (RCTs) has found no conclusive evidence that the anti-inflammatory effect of coffee plays a major role in the reduction of all-cause death noted in observational studies.
Sodium-glucose co-transporter type 2 (SGLT2) inhibitors do not appear to induce an increased rate of venous thromboembolism in patients with type 2 diabetes as compared with dipeptidyl peptidase-4 (DPP-4) inhibitors, which provides reassurance in terms of the thromboembolic safety of the former, according to a recent study.
Monitoring of blood counts occurs more frequently than is necessary and does not seem to influence outcomes in patients with acute gastrointestinal (GI) bleeding, reveals a study. However, such practice appears to result in more blood transfusions, suggesting that patient care may be improved by less frequent monitoring.
Diuretic therapy in primary hypertension results in a sustained increase in plasma renin activity (PRA), which is similar across different diuretics classes and is not related to the average reduction in blood pressure (BP), according to the results of a systematic review and meta-analysis.
No conclusive evidence supports the positive effects of consuming edible mushroom on cardiovascular risk factors, but potential health benefits may exist, including a favourable alteration of lipid profiles and blood pressure reduction, a study has found.
In individuals with resected oesophageal or gastro-oesophageal junction (GEJ) cancer who have received neoadjuvant chemoradiotherapy (CRT), adjuvant nivolumab therapy demonstrated superior efficacy over placebo, according to the CheckMate 577 trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.
The effect of cannabidiol (CBD) in the treatment of patients with Lennox–Gastaut syndrome may occur within 7 days of initiation, and most adverse events resolve within a 14-week period, a study reports.
In a webinar held on 27 March 2021, paediatric
endocrinology nurses Karen Blair,
Kate Davies, and Siti Zarina Yaakop shared
insights and clinical experience based
on their frontline roles in caring for patients
with central precocious puberty (CPP)
and supporting their family members.