A lifestyle intervention combining dietary and physical activity counselling initiated during early pregnancy does not appear to effectively improve dietary intake, physical activity, or obstetric and perinatal outcomes in pregnant women at high risk of gestational diabetes mellitus, according to data from the RADIEL trial.
Treatment with 5α-reductase inhibitors improves disease-specific survival following a diagnosis of bladder cancer, suggests a recent study. On the other hand, α-blockers do not appear to improve bladder cancer survival.
The risk of colorectal cancer (CRC) is significantly higher in patients with chronic kidney disease (CKD), regardless of a history of transplant, according to the results of a systematic review and meta-analysis.
Postnatal exposure to household disinfectants may lead to higher infant body mass index at 3 years of age, according to a recent study, which further reports that this relationship is influenced by the gut microbiota at 3–4 months.
There is a strong association between smoking duration and colorectal polyps, independent of smoking intensity, cessation and other potential confounders, reports a recent study. Such association is more robust with distal rather than proximal polyps, and with serrated polyps rather than adenomas.
The causes, presentations and management of anaphylaxis vary considerably with age, according to a recent Singapore study, which reported that children are more likely to present with food anaphylaxis, while drug anaphylaxis is more common in adults.
Low-density lipoprotein cholesterol (LDL-C) levels remained high in many patients with stable or acute coronary heart disease (CHD) in Asia, despite having a very high risk of recurrent cardiovascular (CV) events, indicating that the use of lipid-lowering therapies and lipid monitoring were inadequate.
Substituting diets high in carbohydrates with those high in monounsaturated fatty acids in the context of low saturated fatty acids do not appear to yield favourable effects on blood pressure, according to a meta-analysis.