Multiple sclerosis (MS) is one of the most common neurological disorders – affecting over 2.3 million people globally – and it is the leading cause of nontraumatic disability in young adults. However,the availability of supportive resources and services for people with MS is scarce in many regions of the world. In Malaysia, the prevalence of MS is estimated at 2-3/100,000; the current Malaysian clinical practice guidelines on the management of MS recommend disease modifying agents, such as interferon-β and teriflunomide, as first-line therapeutic agents. In this article, Dr Singer - in partnership with Sanofi and the Malaysian Society of Neurosciences - shares his insights into managing MS dynamically, highlighting the importance of early intervention in improving patient outcomes.
Globally, one in four people will be affected by psychiatric or neurological disorders during their lifetime.1 With an estimated affected population of 450 million people, mental disorders are among the leading causes of ill-health and disability worldwide.1 At the recent Lundbeck Neuroscience Symposium held at Hilton Kota Kinabalu from 3–5 November 2017, three renowned key opinion leaders from the field of psychiatry shared their insights into the optimal management of bipolar disorder and schizophrenia.
At a recent Menarini-sponsored symposium held during the 47th Annual Scientific Meeting of the Malaysian Orthopaedic Association at Kuala Lumpur Convention Centre, Dr Magdi Hanna spoke on the importance of effective postoperative pain management, highlighting the role of multimodal combination therapy in improving treatment outcomes.
At a recent Lundbeck Neuroscience Symposium at Hilton Kota Kinabalu, Professor Bernhard Baune discussed important clinical considerations in the management of behavioural and psychological symptoms of dementia (BPSD), focussing on the role of memantine hydrochloride (Ebixa®; Lundbeck).
In this issue of MIMS PsychiatrySupplement, we bring you clinical updates related to managing depression and optimizing functional recovery in patients with depression, as well as a symposium highlight of the Lundbeck Malaysia Neuroscience Symposium.
In this issue of MIMS Cardiology Supplement, we bring you clinical updates related to combating hypercholesterolaemia, highlighting the role of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in lowering low-density lipoprotein-cholesterol levels.
A strong belief in the necessity of medication is associated with better adherence to oral disease-modifying antirheumatic drugs (DMARDs) or prednisone, while higher self-efficacy correlates with poor adherence, in a diverse cohort of patients with rheumatoid arthritis (RA), suggests a study.
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.
Apixaban slashes the risk of recurrent venous thromboembolism (VTE) by 90 percent in cancer patients compared with the low-molecular-weight heparin (LMWH) dalteparin, with no increase in major bleeding risk, according to the ADAM VTE study presented at ASH 2018.