Dr. Michael Sze, Dr. Tammy Ma, Dr. Yui-Ming Lam, 20180409000000
A 47-year-old gentleman with a known history of mitral valve prolapse (MVP) and mild-to-moderate mitral regurgitation since his 30s presented to Queen Mary Hospital with sudden onset of chest pain and palpitations for 1 day.
Chronic kidney disease (CKD) has a global prevalence of 7–12 percent, with a mortality risk that has increased over the past 25 years – ranking 25th in 1990 to 17th in 2015. While there is no sufficient data reflecting the incidence of CKD in South East Asia (SEA), in Singapore, 2.3 percent of adults aged 18–69 years have been found to have renal impairment (estimated glomerular filtration rate [eGFR] of <60 mL/min/1.73m2).
Rates of burnout within the medical profession are significant. Studies from across the world quote rates of 12–80 percent, depending on which dimension of burnout is studied. Prevalence varies according to specialty, gender, age or career stage, and practice setting.
The syndrome of sensory neuronopathy and detection of anti-Hu antibody in 2010 were very strong indications of the presence of a malignant tumour. In a series of 200 patients positive for anti-Hu, 83.5 percent were found to have cancer, and 90 percent of the cancer cases were small-cell lung cancer.
Volunteerism is defined as the practice of volunteering one’s time or talents for charitable or other worthwhile activities. It is usually deeply personal and never pays the bills. While it may be hard for many to understand, for some it is their calling in life and they’d have it no other way. MIMS Doctor had the opportunity to speak to Dato’ Dr. Musa Mohd Nordin, advisor of IMAM Response & Relief Team (IMARET) about his work with the marginalized and underprivileged children not only in Malaysia, but also around the world.
Dr Michael Lim, consultant of the Division of Paediatric Pulmonary and Sleep in National University Hospital, Singapore, shares his insights with Pearl Toh on diagnosing and managing paediatric asthma in the primary care setting.
Prof. Cheuk-Chun Szeto, Dr. Winston W. S. Fung, 20180125045128
A 65-year-old lady with a background of type 2 diabetes, hyperlipidaemia and chronic immune thrombocytopenia presented to us with a 2-week history of generalized malaise and myalgia. Shortly after the onset of myalgia, she was noted to have reduced urine output and the urine was described as dark in colour. Her regular medications included prednisolone, danazol, simvastatin, metformin, and human insulin. Upon further questioning, the patient admitted that her compliance to simvastatin and danazol used to be poor. However, she recently started to take both medications regularly after repeated education.
A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.
Use of mirabegron in the treatment of men with overactive bladder (OAB) appears to effectively alleviate urgency and storage symptoms, but not reduce the frequency of micturition episodes, according to data from the MIRACLE study.