For long-term users of combined oral contraceptives (COC), short-term hormonal withdrawal that occurs during the once-a-month pill pause appears to be accompanied by a significant increase in negative affect, anxiety, and mental health symptoms, regardless of COC type, as reported in a study.
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1RAs) results in significant weight loss in patients with obesity or overweight without diabetes, a study has shown. In addition, the best GLP-1RA agent appears to be semaglutide, showing superior efficacy and low-to-moderate risk of side effects.
A large retrospective cohort study by the University of Hong Kong (HKU) finds that postoperative prescription of opioids is associated with increased risks of new persistent opioid use, 30-day emergency department visits, 30-day readmission, and 30-day all-cause mortality.
Aldosterone synthase inhibition with lorundrostat confers substantial blood pressure (BP)-lowering benefit in people with uncontrolled hypertension, while having a favourable safety profile, according to data from the phase II Target-HTN trial.
Using content on older adults mined from TikTok, one of the fastest growing social media platforms today, researchers from the National University of Singapore (NUS) found that negative encounters with older adults significantly predicted negative age stereotyping.
Higher blood concentrations of heavy metals appear to contribute to chronic kidney disease (CKD), while elevated levels of plasma selenium and serum zinc reduce CKD risk, according to a Singapore study.
Researchers from the Chinese University of Hong Kong (CUHK) have developed magnetic hydrogel micromachines with active release of antibacterial agents for biofilm eradication in small tubular medical implants.
Frequent intake of high-protein foods in diets, especially those derived from animals, appears to be associated with an increased risk of atopic dermatitis (AD) and allergic sensitization to common house dust mites, according to a study.