Using regional citrate for anticoagulation during dialysis significantly extends the lifespan of dialysis filter compared with systemic heparin anticoagulation, although this has no impact on the patients’ mortality rate over 1 year, according to the RICH study presented at ASN 2020.
The efficacy of lanifibranor in reducing histological markers of non-alcoholic steatohepatitis (NASH) is comparable in patients with and without type 2 diabetes (T2D), according to the phase IIb NATIVE study presented as a poster at AASLD 2020.
Closer adherence to a Mediterranean-type diet appears to reduce the risk of progression to large drusen and to late age-related macular degeneration (AMD), with the signal being greater for geographic atrophy (GA) than neovascular AMD, as shown in a retrospective analysis of two controlled clinical trials cohorts, namely Age-Related Eye Disease Study (AREDS) and AREDS2.
Use of the potent and selective PPARδ* agonist seladelpar led to improvements in histologic responses and liver chemistry in patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH), a phase II study has shown.
Breast cancer patients face a high risk of skeletal-related events (SREs), particularly when diagnosed at advanced stages, reports a new Indonesia study presented at the recently concluded 2020 Asia Virtual Congress of the European Society of Medical Oncology (ESMO Asia 2020). Oncological and reproductive factors seem to affect this risk and may be worth monitoring for.
Dr Rajneesh Kumar, a senior consultant at the Department of Gastroenterology and Hepatology, Singapore General Hospital, highlights the high prevalence of hepatitis, and speaks to Roshini Claire Anthony about the transmission, prevention, and treatment of the disease.
For inflammatory bowel disease patients undergoing ileocolonoscopy, deep sedation with propofol beats moderate sedation with midazolam and fentanyl hands down, owing to less pain, more amnesia, and better experience, a study reports.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.