Treatment with fruquintinib, an oral VEGFR* inhibitor, significantly improves overall survival (OS) among Chinese patients with metastatic colorectal cancer (CRC) in the third-line setting, according to the FRESCO** study.
Women with pre-eclampsia or gestational hypertension during their first pregnancy had an increased risk of developing chronic hypertension, type 2 diabetes (T2D), and hypercholesterolaemia than those who were normotensive during pregnancy, according to a study. The risk persisted for several decades later, signalling these hypertensive disorders of pregnancy (HDP) as red flags for cardiovascular (CV) health for life.
Older individuals with osteoporosis who adopt a Mediterranean diet and take vitamin D supplements may experience significant improvements in femoral neck bone mineral density (BMD), according to the European-based NU-AGE* trial.
Statistically, augmented empirical prophylaxis (AEP) is superior to single agent empirical (SAEP) and targeted prophylaxis (TP), according to a large retrospective study. In some patients, sepsis has developed despite receiving a prophylactic antibiotic to which the sepsis-causing bacteria are sensitive.
Robot-assisted radical cystectomy was noninferior to open surgery for progression-free survival (PFS) at 2 years in patients with bladder cancer, while improving perioperative parameters without compromising oncological outcomes and overall surgical complications, according to the phase III RAZOR* study.
Older individuals who are both frail and malnourished have a higher risk of functional disability and poor quality of life (QoL) compared with their more robust or well-nourished counterparts, according to results of a study from Singapore.
Implementation of the 2017 American College of Cardiology (ACC)/American heart Association (AHA) hypertension guidelines will substantially increase the number of people labeled as hypertensive and treated with drugs in both the US and China, according to a study. More than half of those aged 45–75 years in both countries can be considered as having hypertension.
In people at high risk of atrial fibrillation, the use of a self-applied, home-based wearable electrocardiogram (ECG) patch improves immediate monitoring and leads to higher rates of diagnosis compared with delayed monitoring, a recent study has shown.
Nonsteroidal anti-inflammatory drugs (NSAIDs) appear to increase the risk of major bleeding, stroke or systemic embolism, and hospitalization among patients with atrial fibrillation (AF), suggest the results of the RE-LY* trial. Moreover, there is no difference in the safety and efficacy of dabigatran etexilate (DE) 150 and 110 mg twice daily relative to warfarin.
Diabetic patients in a decompensated state and who develop type 2 myocardial infarction (MI) have an increased risk for mortality and major adverse cardiac events (MACE), according to a new study. In addition, these patients are potentially at risk for undiagnosed coronary artery disease.
Although many patients with atopic dermatitis (AD) use antihistamines, no high-level evidence exists to prove that nonsedating antihistamines reduce itch in patients with AD or provide benefit in controlling AD symptoms, except perhaps sleep and AD comorbidities such as allergic rhinitis, according to a study.