Using point-of-care testing (POCT) of C-reactive protein (CRP) to guide antibiotic prescribing in primary care clinics led to reduced antibiotic use for acute exacerbations of chronic obstructive pulmonary disease (COPD) without compromising clinical outcomes, the PACE* study finds.
A combination of tocilizumab and methotrexate reduced disease activity at 2 years compared with methotrexate plus prednisone in patients with early rheumatoid arthritis (RA), an effect not demonstrated with tocilizumab monotherapy.
Marketplace introduction of the antitumour necrosis factor (anti-TNF) therapy infliximab seems to have little appreciable impact so far on the rates of inflammatory bowel disease (IBD)-related hospitalizations or intestinal resections among patients with Crohn’s disease (CD) or ulcerative colitis, despite robust penetration of the drug in the CD population, as reported in a recent study from Canada.
Imaging of prostate specific membrane antigen (PSMA) targeted radiotracers appears to be useful in detecting biochemically recurrent prostate cancer at low prostate-specific antigen (PSA) levels, suggest the results of a systematic review and meta-analysis.
A handheld ultrasound device, which uses an integrated algorithm for measurements, provides epidural depth estimates comparable to those obtained with a console ultrasound machine, according to a new study.
Levodopa-induced complications can lead to significant worsening of quality of life (QoL) in Asian patients with Parkinson’s disease (PD), necessitating that clinicians monitor their patients closely and promptly manage such complications, according to a longitudinal local study.
Patients referred to home hospice care following non-cancer diagnoses had their preventative medications significantly reduced between admission and death, though this did not apply to patients with cancer referred to hospice care, a retrospective study from Singapore showed.
Exposure to acid suppression therapy, such as proton pump inhibitors, within the first year of life appears to pose an increased fracture risk in children, with the risk amplified by days of use and earlier initiation, a study has found.
Symptomatic pericardial effusions are most commonly caused by cancer and iatrogenic complications, results of a Singapore study in an academic medical centre have found. Nonetheless, success rate is high and complications are relatively low in pericardiocentesis.
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from a large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.