Statins may have therapeutic potential in chronic obstructive pulmonary disease (COPD), improving exercise tolerance, lung function and health-related quality of life, especially in patients with comorbid cardiovascular disease, elevated systemic inflammation or hyperlipidaemia, according to a recent study.
Switching from bilevel positive airway pressure (BiPAP) to continuous positive airway pressure (CPAP) ventilation therapy may be safe and cost-effective in patients with obesity hypoventilation syndrome and sleep apnoea, a small study presented at the ERS 2017 has shown.
Initiating therapy with fluticasone furoate plus vilanterol resulted in improved asthma control over usual care in individuals with symptomatic asthma, according to results of the Salford Lung Study presented at ERS 2017.
A new score that measures fibrosis in subcutaneous adipose tissue (scAT) may identify poor responders to Roux-en-Y gastric bypass (RYGB), a common weight-loss procedure for morbid obesity, a study has shown.
Hormone replacement therapy (HRT) may help delay lung function decline in middle-aged women, according to results of a longitudinal analysis presented at ERS Congress 2017, demonstrating a possible role for female sex hormones in the preservation of lung function.
Use of sirukumab at 100 mg every 2 weeks and 50 mg every 4 weeks may yield significant reductions in rheumatoid arthritis (RA) symptoms, according to the SIRROUND-D study. The drug inhibits structural damage progression and improves physical function and quality of life in patients refractory to conventional disease-modifying antirheumatic drugs (DMARDs), while demonstrating an acceptable safety profile.
Rucaparib maintenance therapy increases progression-free survival (PFS) in BRCA-mutant recurrent ovarian cancer (OC) by 77 percent, according to late-breaking results from the ARIEL3 trial presented at the European Society for Medical Oncology (ESMO) 2017 Congress in Madrid, Spain.
Insulin degludec/insulin aspart reduced the rates of overall and nocturnal severe hypoglycaemia compared with biphasic insulin aspart 30 in Muslim individuals with type 2 diabetes mellitus (T2DM) who fast during Ramadan, according to data presented at EASD 2017.
CT-based surveillance, recommended by major international guidelines during the first 2 years after complete resection of non-small-cell lung cancer (NSCLC), has demonstrated no significant overall survival (OS) benefit over less intensive surveillance with clinical examinations and chest X-rays (CXR) only, according to a study presented at the European Society for Medical Oncology (ESMO) 2017 Congress in Madrid, Spain.
Ertugliflozin 15 mg once daily is noninferior to the sulphonylurea glimepiride in HbA1c reduction over 52 weeks in patients with type 2 diabetes (T2D) who are inadequately controlled on metformin, according to the VERTIS SU* trial presented at the EASD 2017 in Lisbon, Portugal.
The addition of the glucagon-like peptide-1 analogue semaglutide to standard of care resulted in sustained reduction in weight and waist circumference in individuals with type 2 diabetes (T2D) with high cardiovascular risk, according to the phase III SUSTAIN 6* trial presented at EASD 2017.
The additional use of intermittent low-energy diet (LED) or daily meal replacements after a mean 10-percent weight loss and 1-year maintenance effectively maintains weight loss in obese patients with knee osteoarthritis for 3 years, according to a recent study.
A recent study has found that food bolus impaction or strictures predict most episodes of oesophageal perforation, a rare but serious complication of eosinophilic esophagitis (EoE) that occurs in about 2 percent of cases. This suggests that patients with fibrostenotic disease due to longer duration of symptoms are at increased risk.