Management of most patients with heart failure occurs at an outpatient level, with the GP playing a central role in initial diagnosis, counselling, regular assessment of fluid status, titration and monitoring of medications and end-of-life care.
In this series, we present authoritative advice on the investigation of a common clinical problem, especially commissioned for family doctors and written by members of the Royal Australasian College of Physicians.
New therapies that specifically target inflammatory pathways or aberrant physiology in severe asthma offer substantial opportunities for effective treatment. Some of these therapies are available under specialist referral, and others are available in the context of clinical trials.
In patients with a renal stone, management aims to detect complications, triage to expectant observation or active intervention and identify any predisposing factors. Referral for active urological intervention or detailed metabolic evaluation may be indicated. Dietary and lifestyle interventions may help decrease the risk of recurrences.
Dr. Hang Wun Raymond Li, , Prof. Pak-Chung Ho, 20160601080000
Infertility is defined as failure to achieve pregnancy after one year of regular unprotected intercourse. It is a significant global problem with a prevalence of approximately 1 in 7 couples.1 Male factor is a common diagnostic category, and as a single factor it accounts for approximately 20% of the infertile couples.2, 3
Pregnancy is a proinflammatory state with activation of endothelial cells while operative delivery and genital tract injury can result in endothelial damage. Venous dilatation and compression of pelvic veins by the gravid uterus encourages venous formation in the lower limbs.
A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.
Use of mirabegron in the treatment of men with overactive bladder (OAB) appears to effectively alleviate urgency and storage symptoms, but not reduce the frequency of micturition episodes, according to data from the MIRACLE study.