Gingival bleeding appears to influence the association between periodontal diseases and blood pressure (BP), a study has shown. However, the burden represented by periodontitis is still vital. Periodontal assessment may be essential in difficult to control hypertension.
A growing waistline increases the risk of incident low physical function in the following year among adults with knee osteoarthritis (OA), suggests a recent study. Maintaining waist circumference (WC) may prevent the development of low physical function.
Romilkimab, a novel bispecific immunoglobulin-G4 antibody that binds and neutralizes interleukin (IL)-4/IL-13, shows promise in the treatment of diffuse cutaneous systemic sclerosis, producing significant reduction in skin fibrosis, according to the results of a phase II trial.
Women with high levels of very low-density lipoprotein cholesterol or high apolipoprotein B to A-1 ratio may fare better with insulin than metformin, with a recent study showing that treatment with the latter leads to higher serum concentrations of triglyceride-rich lipoproteins in the last trimester of pregnancy.
High-acuity medically critically ill patients who achieve time–weighted average daily blood glucose levels <180 mg/dL while in the intensive care unit (ICU) have a significantly lower likelihood of subsequent hospital mortality, a study has found.
In the treatment of schizophrenia, patients on typical antipsychotics have better memory than those taking clozapine or risperidone, and patients on clozapine have better language function compared with those on risperidone, as shown in a study.
Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.
Diabetes, hypertension, and older age are associated with lower hospital readmission in patients with gastroparesis, while higher length of stay (LOS), drug abuse, and marijuana use increase the 30-day readmission rate, a study has shown.