Men with nonmetastatic castration-resistant prostate cancer (nmCRPC) who have rapidly rising levels of prostate-specific antigen (PSA) see radiographic progression of their malignancy even without meeting the criteria set by the Prostate Cancer Working Group 2 (PCWG2), a recent study has shown.
A risk prediction model based on high-resolution computed tomography (HRCT) variables appear useful for patients with rheumatoid arthritis (RA)-associated interstitial lung disease (ILD), suggests a study.
A pulmonary rehabilitation programme for chronic obstructive pulmonary disease (COPD) yields sustained improvements in anxiety and quality of life of patients over 2 years, a study has shown. However, the positive changes in dyspnoea, depression, and stress symptoms may only last short term.
Among patients with type 2 diabetes mellitus (T2DM), plasma levels of xanthine oxidoreductase (XOR) share a close relationship with circulating levels of liver transaminases, a new study has found. This interaction suggests that XOR may find use as an indicator of liver damage in these patients.
Patellofemoral osteoarthritis (PFOA) symptoms are associated with higher odds of depressive symptoms, catastrophizing, and temporal summation (TS), regardless of magnetic resonance imaging (MRI) PFOA status, reports a recent study. In addition, males with PFOA symptoms without MRI PFOA exhibit local hyperalgesia.
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.
Invasive fungal infections, particularly those caused by Candida species, are common in hospitalized, immunocompromised, or critically ill patients and are associated with considerable morbidity and mortality.