International Stroke Conference 2022 (ISC 2022)

Endovascular therapy has added value in patients with acute large vessel occlusion

Roshini Claire Anthony, 20220311180001

Endovascular therapy (EVT) in addition to medical therapy appeared to improve outcomes in patients with acute large vessel occlusion (LVO) with large ischaemic core following a stroke, according to results of the RESCUE-Japan LIMIT* trial.

Maternal stroke tied to high morbidity, mortality

Elaine Soliven, 20220225000000

Women who experienced a stroke during pregnancy had higher rates of morbidity and mortality compared with those without stroke, according to a study presented at ISC 2022.

DOACs as effective as warfarin in CVT with lower bleeding risk

DOACs as effective as warfarin for CVT with lower bleeding risk

Roshini Claire Anthony, 20220224180001

The risk of recurrent venous thrombosis in patients with cerebral venous thrombosis (CVT) was comparable between those who received warfarin or direct oral anticoagulants (DOACs), according to results of the ACTION-CVT* study presented at ISC 2022.

Tenecteplase still feasible up to 24 hours after a stroke

Elvira Manzano, 20220224000000

Intravenous thrombolysis with tenecteplase up to 24 hours after a stroke appears to re-establish blood flow in patients with large-vessel acute ischaemic stroke selected with advanced imaging, the phase IIa CHABLIS-T study has shown.

High BP in young adulthood tied to midlife brain changes

High BP in young adulthood tied to brain changes in midlife

Pearl Toh, 20220222140100

Having high blood pressure (BP) during age 20-40 years appears to be associated with brain changes in midlife which may increase the risk of cognitive decline in later life, according to data from the Coronary Artery Risk Development in Young Adults (CARDIA) study presented at ISC 2022.

Stroke risk elevated first 3 days post–COVID-19 diagnosis

Roshini Claire Anthony, 20220218180001

Older patients with COVID-19 may have an increased risk of being hospitalized for acute ischaemic stroke (AIS), particularly in the first 3 days following their COVID-19 diagnosis, according to a study presented at ISC 2022.

Heart attack tied to decline in cognitive function later in life

Elaine Soliven, 20220218000000

Myocardial infarction (MI) was associated with a rapid decline in cognitive function, such as global cognition, executive function, and memory, years after the event, according to a study presented at ISC 2022.

Intra-arterial tPA boosts benefit of stroke thrombectomy

Pearl Toh, 20220217140100

Adjunct thrombolysis with intra-arterial alteplase (tPA) following a successful thrombectomy in patients with acute ischaemic stroke due to large vessel occlusion (LVO) significantly improves neurologic outcomes at 90 days, according to the CHOICE* study presented at ISC 2022.

Tirofiban may improve outcomes in LAA strokes

Audrey Abella, 20220216170752

While additional tirofiban prior to endovascular treatment (EVT) did not appear to benefit stroke patients with large vessel occlusion (LVO), it did seem to have an advantage for those with large artery atherosclerosis (LAA), findings from the RESCUE BT trial have shown.

The mouth a gateway to stroke risk reduction?

Audrey Abella, 20220216053132

In individuals who had a recent stroke or transient ischaemic attack (TIA), a trip to the dentist might just spare them from a recurrence, findings from the PREMIERS* study suggest.