Selective internal radiation therapy (SIRT) with yttrium-90 resin microspheres does not improve overall survival (OS) vs sorafenib in patients with locally advanced hepatocellular carcinoma (HCC), although it significantly improves tumour response and reduces adverse events (AEs), the phase III SARAH study has shown.
In patients with liver-only or liver-dominant metastatic colorectal cancer (mCRC) with right-sided primary tumours, addition of selective internal radiation therapy (SIRT) to first-line mFOLFOX6 chemotherapy significantly improves overall survival (OS), according to results of a study presented at the European Society for Medical Oncology (ESMO) 19th World Congress on Gastrointestinal Cancer (WCGC 2017) held in Barcelona, Spain.
Liquid biopsy at disease progression effectively identifies novel and heterogeneous mechanisms of acquired resistance to targeted therapies in patients with a range of gastrointestinal (GI) cancers, which may help guide subsequent therapy.
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Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.
Empagliflozin treatment in patients with type 2 diabetes mellitus exerts beneficial effects on cardiovascular (CV) risk factors, including blood pressure and uric acid, according to a systematic review and meta-analysis.
A 10 or 20 mg/kg daily dose of cannabidiol could almost halve the risk of seizures in children with Dravet syndrome, according to the phase III GWPCARE2* study presented at the American Academy of Neurology annual meeting (AAN 2019).