Treatment with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI), a LAMA/ICS/LABA combination, significantly improves trough FEV1* in symptomatic patients with inadequately controlled asthma compared with FF/VI only, according to the CAPTAIN** study presented at AAAAI 2020.
Treatment with omalizumab, an anti-IgE monoclonal antibody, significantly improves outcomes in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP), regardless of asthma status, based on a pooled analysis of the POLYP 1 and POLYP 2* studies presented at AAAAI 2020.
Post hoc analyses of the LIBERTY AD SOLO 1 & 2* and ADOL** trials demonstrated significant reductions in pruritus, anxiety, and depression with dupilumab in adults and adolescents with moderate-to-severe atopic dermatitis (AD).
Adults who develop peanut allergy in adulthood are less likely to receive a physician diagnosis of their allergy or use epinephrine compared with those with childhood-onset peanut allergy, according to a study from the US.
Treatment with baricitinib led to clinically meaningful improvements in itch and skin symptoms in patients with moderate-to-severe atopic dermatitis (AD), even in those with additional comorbid atopic conditions, according to a pooled analysis of two phase III studies released in the AAAAI 2020 Meeting.
Three studies initially scheduled for presentation at AAAAI 2020 demonstrated that epinephrine delivered intranasally was more rapidly absorbed and led to greater haemodynamic response compared with epinephrine delivered intramuscularly.
The investigational IGSC-C 20%* was noninferior and bioequivalent to, and had a similar safety profile with, IGIV-C 10%** for the treatment of primary humoural immunodeficiency (PI)***, highlighting the former’s potential as immunoglobulin (Ig)G replacement therapy for immune prophylaxis, according to phase III data presented at AAAAI 2020.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.
Use of thyroid hormone therapy does not seem to protect older adults with subclinical hypothyroidism against mortality, but it appears to confer survival benefits to those aged <65 years, results of a study have shown.