Due to the apparent risk of adverse outcomes of disease and adverse events (AEs) associated with short-acting beta-agonists (SABA), the Global Initiative for Asthma (GINA) 2019 guideline recommends that all patients with mild asthma should receive symptom-driven or regular low-dose inhaled corticosteroid (ICS)−containing controller treatment.
Since the advent of immunotherapy, a more than three-fold increase in median overall survival (OS) has been seen in lung cancer patients over the past 10 years, according to data presented at the Advances in Medicine 2019 conference organized by the Chinese University of Hong Kong (CUHK).
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In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.