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Multidisciplinary
Top Medical News
Patients with cardiac inherited disease (CID) tend to overestimate their risk for severe cardiac events, a recent study has found. This usually coincides with reporting mild symptoms of anxiety.
Among middle-aged and older adults, sleeping poorly is related to general and abdominal obesity, short sleep duration to both sarcopaenic and general obesity, and depression to sarcopaenia, as suggested in a study.
The risk of cardiovascular diseases (CVDs) appear to be lower among survivors of prostate cancer, a recent study has found.
Septal myectomy is a safe procedure, bearing minimal risk of early mortality and adverse events, a recent study has found.
Faecal lactoferrin (FL) shows high sensitivity and modest specificity in the assessment of inflammatory bowel disease (IBD) activity, with greater ability to evaluate ulcerative colitis (UC) rather than Crohn’s disease (CD), according to the results of a systematic review and meta-analysis.
Increased acid exposure on pretransplant impedance-pH testing may lead to the development of bronchiolitis obliterans syndrome (BOS) and chronic lung allograft dysfunction (CLAD), both of which are measures of chronic allograft rejection, after lung transplantation, suggests a recent study.
Infants born to mothers with the coronavirus disease 2019 (COVID-19) during the third trimester of pregnancy do not show altered cellular or humoral immunity, nor do they have unbalanced lymphocyte differentiation, according to a recent study.
Special Reports
In this fourth issue,
join us as we discover the unique biology Asians have with respect to diabetes.
Take a closer look at trials evaluating whether empagliflozin’s cardiovascular
and renal benefits – as analysed in Asians – are consistent with the overall
trial population, and how it addresses unmet needs.
The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illness. On the first day, eminent local and internationalexperts weighed in on the treatment of major depressive disorder (MDD), including in the elderly and incases of coexisting anxiety.
At the Novartis-sponsored VERIFY Soft Launch held at Le Meridien, Kuala Lumpur, two distinguished speakers spoke on the latest updates in glucose-lowering therapy and the benefit of early treatment intensification using combination therapy (ie, vildagliptin/metformin) in the management of T2DM.
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Hyperkalaemia (HK) occurrence and recurrence are frequent in advanced CKD*, creating a perfect storm for cardiovascular events and death, says Professor Juan-Jesus Carrero from the Karolinska Institute, Solna, Sweden, at ERA-EDTA 2020. Given these risks, acutely elevated potassium (K+) should merit clinical attention.
Roxadustat treatment for anaemia in patients with dialysis-dependent chronic kidney disease (DD CKD) does not come with an increased risk of ophthalmic abnormalities, according to a phase III trial conducted in Japan.
Roxadustat may be a suitable treatment for anaemia in patients with non-dialysis dependent (NDD) chronic kidney disease (CKD), the phase III Dolomites* study showed.
Dapagliflozin 5 mg and 10 mg FC tab
Conference Reports
Treatment with ipatasertib plus paclitaxel in the first-line setting demonstrated a trend toward improved overall survival (OS) compared with paclitaxel alone in women with inoperable locally advanced/metastatic triple-negative breast cancer (TNBC), according to final results of the phase II LOTUS trial.
Vitamin D supplementation can reduce the incidence of advanced cancer among older adults, in particular those with a normal BMI but not those who are overweight or obese, suggests the large VITAL* randomized study presented during the ASCO 2020 Meeting.
The anti-interleukin 17A antibody netakimab reduces disease activity and skin manifestations in patients with active psoriatic arthritis (PsA), consequently improving patient-reported outcomes (PROs), analyses of the phase III PATERA trial have shown.
The investigational JAK1* inhibitor filgotinib was noninferior to adalimumab in reducing disease activity in patients with moderate-to-severe rheumatoid arthritis (RA) who had inadequate response to methotrexate (MTX-IR), according to the FINCH 1 study presented at EULAR 2020 Virtual Meeting.
Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.
Long-term use of onabotulinumtoxinA led to reductions in monthly headache days (MHDs) in adults with chronic migraine (CM), according to post hoc analyses of the COMPEL* study presented at the AHS 2020 virtual scientific meeting.
Treatment with apremilast, an oral phosphodiesterase 4 inhibitor, significantly reduced the number of oral ulcers in patients with Behcet’s syndrome, according to the RELIEF* study presented at EULAR 2020.
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