Top Medical News
25 minutes ago
Thrombocytopoenia increases the risk of bleeding, poor cardiovascular outcomes and death among patients with acute myocardial infarction, a recent study suggests.
3 hours ago
Pubertal timing is implicated in self-harm in females, such that older age at menarche is associated with a lower risk of self-harm both in adolescence and adulthood, a recent study suggests.
Pearl Toh, 14 hours ago
Exposure to secondhand smoke during childhood is associated with an increased risk of atrial fibrillation (AF) later in life, thus presenting childhood secondhand smoke exposure as a modifiable risk factor for AF, the Framingham Heart Study finds.
15 hours ago
Both adalimumab and phototherapy increase overall and skin-related quality of life (QoL) in psoriasis patients, although phototherapy appears to be better, a recent study has shown.
Roshini Claire Anthony, 19 hours ago

The mortality rate for patients who undergo percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) for de-novo three-vessel disease or left main coronary artery disease (CAD) is comparable at 10 years. However, CABG may be preferable for those with three-vessel disease, according to the SYNTAX Extended Survival (SYNTAXES) study, a 10-year follow-up of the SYNTAX* trial.

Jairia Dela Cruz, 20 hours ago
Binge drinking in Singapore is less prevalent than internationally, and most binge drinkers engage in the practice only now and then, as reported in a recent study. Despite this trend, binge drinking is associated with a myriad of mental health conditions and reduced quality of life.
20 hours ago
Low-risk histopathologic features at primary enucleation are predicted by the presence of macular sparing, optic nerve visibility, <1 quadrant of retinal detachment (RD) or a combination thereof, which suggest safe trial eye salvage, according to a study. No clinical sign is associated with high-risk histopathologic features.
Special Reports
11 Sep 2019
At the recent 10th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress(MAC) held in Hilton Kuala Lumpur, Dr Wong Ming, a consultant endocrinologist from Sunway Medical Centre, spoke on the role of non–high-density lipoprotein cholesterol (non–HDL-c) as an emerging marker and treatment target for cardiovascular (CV) disease. Additionally, she also highlighted the role of fenofibrate in delaying and preventing diabetic retinopathy (DR).
Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
Prof. Rafael R. Castillo, Dr. Hyo Seung Ahn, 20 Aug 2019
Major trials have demonstrated the benefits of beta-blockers in the treatment of hypertension.1 At a recent symposium held during the Asian Pacific Society of Cardiology 2019 Congress in Manila, Philippines, experts discussed the latest guidelines on hypertension treatment, with a focus on the role of the 3rd generation beta-blocker, nebivolol. The symposium was chaired by Dr Dante D. Morales, Clinical Associate Professor at the University of the Philippines College of Medicine, and featured renowned cardiologists Prof Rafael R. Castillo and Dr Hyo Seung Ahn.
19 Aug 2019
The cost of hospitalization for complications associatedwith influenza can be reduced significantly through theprevention of influenza infection.5 Cost savings mayincrease exponentially if one considers the control ofinfluenza outbreaks, especially in the aged care homesetting.
14 Aug 2019
Renal cell carcinoma (RCC) is the most common primary tumour arising from the kidney, constituting approximately 80–85% of primary renal neoplasms. According to the Malaysian National Cancer Registry Report 2007–2011, RCC accounts for 62.8% of all kidney cancers nationwide. RCC typically occurs approximately 50% more commonly in men compared with women, and predominantly occurs in the sixth to eighth decade of life.
23 Jul 2019
In an environment where children can interact openly, highly infectious diseases, such asinfluenza, have the potential to spread among childrenand those they come in contact with. Once infected,parents or siblings may have to take time off work or school to recover and to avoid spreading the disease to other healthy individuals.
22 Jul 2019
Coenzyme Q10 (CoQ10, ubiquinone) is a fat-soluble, potent physiological antioxidant that is required for the production of cellular adenosine triphosphate (ATP). CoQ10 can be obtained through tissue synthesis and diet, and it has been widely studied in patients with cardiovascular (CV) risk factors. The effects of oral CoQ10 supplementation in different patient subgroups are presented here.
Conference Reports
Roshini Claire Anthony, 20 Sep 2019

The mortality rate for patients who undergo percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) for de-novo three-vessel disease or left main coronary artery disease (CAD) is comparable at 10 years. However, CABG may be preferable for those with three-vessel disease, according to the SYNTAX Extended Survival (SYNTAXES) study, a 10-year follow-up of the SYNTAX* trial.

Audrey Abella, 20 Sep 2019
Subgroup evaluations of the GLOBAL LEADERS trial demonstrated the anti-ischaemic efficacy of long-term ticagrelor monotherapy relative to aspirin monotherapy in patients who had percutaneous coronary intervention (PCI). However, this occurred at the expense of bleeding in the elderly.
Audrey Abella, 17 Sep 2019
The potent P2Y12 inhibitor prasugrel significantly reduced the incidence of death, myocardial infarction (MI), or stroke in patients with acute coronary syndrome (ACS) with or without ST-segment elevation (STE) compared with ticagrelor, according to the results of the ISAR-REACT* 5 trial presented at ESC Congress 2019. Moreover, the improved anti-ischaemic efficacy of prasugrel was not accompanied by an increased bleeding risk.
Pearl Toh, 16 Sep 2019
A single testing of cardiac troponin I using a high-sensitivity assay can effectively rule out myocardial infarction (MI) without compromising safety, according to the HiSTORIC* study presented at the ESC 2019 Congress.
Roshini Claire Anthony, 16 Sep 2019

A newly developed clinical risk score can identify patients with type 2 diabetes (T2D) at greatest risk for hospitalization for heart failure (HHF) who would derive the most benefit from treatment with dapagliflozin, according to a study presented at ESC 2019.

16 Sep 2019
Prof Deepak Bhatt gives a rundown of the findings from THEMIS and THEMIS-PCI
16 Sep 2019
Podcast: Prof Derek Chew explains the importance of a 1-hour troponin T protocol in suspected ACS as discussed in the RAPID-TnT trial
CME Modules
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