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Top Medical News
About one-third of patients with severe asthma who are on high-dose inhaled corticosteroids (ICS) are also receiving excessive doses of oral corticosteroids (OCS), reveals a study presented at the ERS 2019 Meeting.
Transcatheter aortic valve implantation (TAVI) with either balloon-expandable valves or self-expanding valves yields comparable outcomes, according to a new meta-analysis.
Despite being uncommon, intracranial haemorrhages are typically fatal among children with acute leukaemia, a recent study has found.
Rivaroxaban is mostly safe for the treatment of nonvalvular atrial fibrillation (NVAF) in patients with worsening renal function (WRF), a recent study has found.
A recent study has detected left ventricular thrombus in <3 percent of patients who underwent primary angioplasty for ST-elevation myocardial infarction (STEMI). No association exists between the presence of left ventricular thrombus and a higher risk of systemic thromboembolism.
There are no delayed treatment effects with folic acid supplementation, but it appears to be associated with a higher risk of sessile serrated adenomas/polyps (SSA/Ps), a study has found.
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Special Reports
Annual inactivated influenza vaccination is recommendedfor children with chronic asthma owing to its role indecreasing the severity of disease, complications andsecondary infections. In a resource-limited setting, thissegment of patients should be prioritized to receiveinfluenza vaccinations.
Quadrivalent influenza vaccine (split virion, inactivated) 0.5 mL inj
Vonoprazan 10 mg and 20 mg FC tab
Hypertension (HPT) is defined as a persistent elevation of systolic blood pressure (BP) of 140 mmHg or greater and/or diastolic BP of 90 mmHg or greater, taken at least twice ontwo separate occasions. The most recent National Health and Morbidity Survey (NHMS) 2015 that focuses on noncommunicable diseases showed that among adults aged 18 years and older, there was an increase in the prevalence of HPT from 33.6% in 2011 to 35.3%. While the proportion of patients with HPT who have attained good BP control has increased from 34.7% in 2011 to 37.4%, the awareness of the condition among patients remains poor. The prevalence of undiagnosed HPT remains high; hence, it is recommended that every adult aged 18 years and older to check their BP at least once annually, and more frequently in those with risk factors (eg, family history, obese).
The prevalence of non-communicable diseases (NCDs) in Malaysia is on the rise.The main NCDs in Malaysia include hypertension (HPT), diabetes mellitus (DM), and cardiovascular disease (CVD), and they account for 74% of all deaths according to WHO’s NCD country profile 2018 (35% CVD, 16% cancer, 4% chronic respiratory disease, and 16% other NCDs). According to the 2015 National Health and Morbidity Survey, the overall prevalence of three major NCDs, ie, diabetes (17.5%), hypertension (30.3%) and hypercholesterolaemia (47.7%), remained high among Malaysians.
At the recent 10th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress(MAC) held in Hilton Kuala Lumpur, Dr Wong Ming, a consultant endocrinologist from Sunway Medical Centre, spoke on the role of non–high-density lipoprotein cholesterol (non–HDL-c) as an emerging marker and treatment target for cardiovascular (CV) disease. Additionally, she also highlighted the role of fenofibrate in delaying and preventing diabetic retinopathy (DR).
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
Conference Reports
A combination of the CDK 4/6 inhibitor abemaciclib with fulvestrant improved overall survival (OS) in patients with HR+, HER2- advanced breast cancer (ABC), with a trend toward improved outcomes in patients with poor prognosis, according to results of the phase III MONARCH 2* trial presented at ESMO 2019.
Highlights From European Respiratory Society (ERS) International Congress 2019
Preliminary real-world findings of the REALITI-A* study, presented at ERS 2019, have demonstrated a significant reduction in asthma exacerbations with mepolizumab, a result comparable to that of regulatory clinical trials with this drug.
Having elevated blood eosinophil counts (BEC) along with three other clinical characteristics help identify a subgroup of patients with COPD* who are most likely to benefit from benralizumab in terms of exacerbation reduction, according to a prespecified pooled analysis of the phase III GALATHEA and TERRANOVA** trials.
Exposure to air pollution increases the risk of death in infants and impairs lung function in young children, according to two studies presented at the recently concluded International Congress of the European Respiratory Society (ERS 2019).
The use of low-dose indacaterol acetate/mometasone furoate (IND/MF), a long-acting β2-agonist/inhaled corticosteroid (LABA/ICS) combination, significantly improves trough FEV1* in symptomatic patients with poorly controlled asthma, according to the QUARTZ** study presented at ERS 2019.
The use of single-inhaler triple therapy yields meaningful improvements across a range of chronic obstructive pulmonary disease (COPD) endpoints over time compared with dual therapies, according to data from the IMPACT* trial presented at the 2019 European Respiratory Society (ERS) International Congress.
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