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Top Medical News
Exposure to psychotropic drugs and proton pump inhibitors (PPIs) contributes to an increase risk of clinical and nonvertebral fractures in postmenopausal women with severe osteoporosis, according to a study. Furthermore, teriparatide confers superior benefits for reducing the risk of fractures compared with risedronate, irrespective of such an exposure.
Azathioprine (AZA) shows similar safety and efficacy as mycophenolate mofetil (MMF) in preventing chronic kidney rejection in kidney transplant recipients who received low-dose cyclosporine A (CsA) and no steroids, according to the ATHENA* study presented at ASN 2019, thus debunking the belief that MMF is better than AZA.
Women with post-traumatic stress disorder (PTSD) are at increased risk of developing thyroid dysfunction, a study reports.
Roxadustat improves haemoglobin levels vs placebo and epoetin alfa, with similar safety profile, in 8,000 patients with chronic kidney disease (CKD)-related anaemia on- and off-dialysis, according to a pooled efficacy and CV safety analyses of roxadustat, spanning over 13,000 patient exposure years.
Pregnancy does not appear to aggravate the risk of bleeding and venous thromboembolism (VTE) in women with Klippel-Trenaunay syndrome (KTS), a recent study has shown.
Smoking intensity is associated with mortality from genitourinary malignancies, according to a nationally representative study. Moreover, the risk of death from bladder and kidney cancers is significantly higher among individuals who started smoking at a younger age and those who smoke at home.
Treatment with sodium zirconium cyclosilicate in end-stage renal disease (ESRD) patients undergoing haemodialysis (HD) improves potassium balance and lessens the frequency of severe hyperkalaemia episodes, according to a posthoc analysis of the phase IIIB DIALIZE study.
Special Reports
Pertussis is a highly contagious respiratory illness caused by Bordetella pertussis. Despite the introduction of effective infant immunisation programmes and high vaccination coverage, pertussis remains a public health concern.1 Recently, MIMS Doctor spoke to Dato’ Dr Musa Mohd Nordin who gave us some insights into the resurgence of pertussis in Malaysia, highlighting strategies to further strengthen the current vaccine coverage rate (VCR).
At the A. Menarini-sponsored symposium, held during the 8thAssociation of South-East Asian Pain Societies (ASEAPS)Congress at Pullman Hotel Kuching, Malaysia, the importance ofa multidisciplinary approach in the management of osteoarthritis(OA) was discussed. A distinguished panel of speakers reviewedthe role of various types of treatments in the management of OAthrough a hypothetical patient case scenario, and shared theirinsights into some questions commonly asked by physicians,including their recommended strategies for pre- and postsurgeryanaesthesia and analgesia
Influenza infection is often times underrecognised and underdiagnosed in Malaysia even though it may occur at anytime of the year, unlike in temperate countries. Smoking is a well-established risk factor for influenza infection, and it is associated with a more severe disease course, morbidity and mortality. The National Avian Influenza Surveillance System of Thailand reported that current or former smoking is among the risk factors associated with a fatal outcome in patients with influenza.
Invasive meningococcal disease is a life-threatening bacterial infection caused by Neisseria meningitidis that can progress rapidly and cause permanent disability.
Topical silicone gel is considered first-line therapy against scars and is used particularly for the treatment of elevated scars,such as hypertrophic and keloid scars. In this report, Dr Yong shares his clinical experience of using silicone gel as part of his scar management strategies.
Jointly organized by the Malaysian Medical Associationand AstraZeneca to commemorate the launch of QTERN,the Q-UEST Symposium saw three distinguished speakersproviding valuable insights into the landscape of T2DMin Malaysia and discussing the latest treatment optionsavailable in the country.
Annual inactivated influenza vaccination is recommendedfor children with chronic asthma owing to its role indecreasing the severity of disease, complications andsecondary infections. In a resource-limited setting, thissegment of patients should be prioritized to receiveinfluenza vaccinations.
Conference Reports
Azathioprine (AZA) shows similar safety and efficacy as mycophenolate mofetil (MMF) in preventing chronic kidney rejection in kidney transplant recipients who received low-dose cyclosporine A (CsA) and no steroids, according to the ATHENA* study presented at ASN 2019, thus debunking the belief that MMF is better than AZA.
Roxadustat improves haemoglobin levels vs placebo and epoetin alfa, with similar safety profile, in 8,000 patients with chronic kidney disease (CKD)-related anaemia on- and off-dialysis, according to a pooled efficacy and CV safety analyses of roxadustat, spanning over 13,000 patient exposure years.
Treatment with sodium zirconium cyclosilicate in end-stage renal disease (ESRD) patients undergoing haemodialysis (HD) improves potassium balance and lessens the frequency of severe hyperkalaemia episodes, according to a posthoc analysis of the phase IIIB DIALIZE study.
Intensive urate lowering with the combination therapy of verinurad plus febuxostat is successful in lowering the urinary albumin to creatinine ratio (UACR) in patients with type 2 diabetes mellitus (T2DM), albuminuria and hyperuricaemia, according to a study presented at the American Society of Nephrology (ASN) Kidney Week 2019.
Dapagliflozin is able to delay renal disease progression among patients with type 2 diabetes, even in those with normal kidney function, according to a study presented at the recently concluded Kidney Week 2019 of the American Society of Nephrology (ASN 2019).
Several Asian studies evaluating different types of valvular heart disease (VHD) reflected poor clinical outcomes, according to a discussion during ESC Asia 2019.
Podcast: Prof Carolyn Lam speaks on the challenges of managing HF in Asia
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