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Top Medical News
Leuprolide acetate 22.5 mg, a novel 3-month depot formulation, is well tolerated and proves effective in achieving and maintaining testosterone concentration below castration levels in patients with prostate cancer, according to the results of a phase III trial.
With recent recalls of losartan-containing products contaminated by potentially carcinogenic nitrosamines, MIMS speaks to the Malaysian National Pharmaceutical Regulatory Agency (NPRA) for more details.
Poor sleep quality appears to increase the risk of peptic ulcer disease recurrence among elderly adults after Helicobacter pylori infection, suggests a recent study.
Rupatadine at either 10 or 20 mg delivers superior improvements in nasal and ocular symptoms of seasonal allergic rhinitis compared with placebo, with both doses well tolerated by adult and adolescent patients, according to the results of a phase III trial.
Decreased scam awareness in older adults appears to be an early sign of cognitive decline and is associated with a higher risk of Alzheimer’s disease (AD), suggests a recent study.
Results of a systematic review and meta-analysis have shown the efficacy of sotagliflozin treatment among patients with type 1 diabetes (T1D), particularly in improving glycaemic and nonglycaemic outcomes and reducing the incidence of hypoglycaemia and of severe hypoglycaemia.
While hypertensive patients with dizziness have no high-risk profile at baseline, those with vertigo are at an increased risk of stroke mortality and thus must be carefully monitored over years, according to a recent study.
Special Reports
Point-of-care ultrasound (POCUS) has become a very popular diagnostic strategy that can be used in a variety of situations. POCUS is defined as a targeted ultrasound examination performed and interpreted by a physician at their patient’s bedside. It is increasingly recognized as a useful extension to physical examination.
At a webinar hosted by Pfizer, leading Malaysian family medicine specialists Professor Chia Yook Chin andProfessor Sherina Mohd Sidik discussed a host of issues commonly encountered in primary care, includingpreventing cardiovascular (CV) disease, pain control in osteoarthritis (OA) and depression management.
In conjunction with the launch of Abilify Maintena® in Malaysia, Lundbeck Malaysia convened a symposium which saw distinguished speakers discussing the role of long-acting injectable (LAI) antipsychotics, such as aripiprazole (Abilify Maintena®, Lundbeck), in the management of schizophrenia, particularly in the early course of schizophrenia (ie, first-episode schizophrenia, FES).
Dapagliflozin 5 mg and 10 mg FC tab
Sunscreen products commonly contain only filters against ultraviolet (UV) radiation. At a recentdinner symposium organized by Eucerin, Dr Rungsima Wanitphakdeedecha discussed whythis is insufficient and what is required for effective protection against the damaging effects ofsunlight on the skin
At the Eisai-sponsored tea symposium during the 27th Malaysian Urological Conference at Shangri-La Kuala Lumpur, Professor Osamu Yokoyama highlighted the advantages of silodosin (Urief®, Eisai Inc.) in relieving lower urinary tract symptoms associated with benign prostate hyperplasia.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat osteoarthritis and rheumatoid arthritis to reduce joint pain and improve joint function. Dr Sazzli Kasim provides his viewpoint on how the current understanding on cardiovascular safety of NSAIDs should be taken into account when determining optimal analgesic strategies for patients with arthritis.
Conference Reports
A contraceptive vaginal system (Annovera) releasing a combination of segesterone acetate and ethinyl estradiol (SA/EE) effectively inhibits ovulation up to a year even at low systemic levels of SA, reports a review study presented at ENDO 2019.
Individuals with poorly controlled type 2 diabetes (T2D) had greater HbA1c reductions and weight loss when a 7 or 14 mg/day dose of the GLP-1* receptor agonist semaglutide rather than sitagliptin was added to their background diabetic medications, results of the phase IIIa PIONEER 3** trial showed.
Systolic blood pressure (SBP) above 129 mm Hg was associated with an increased risk of dementia in middle-aged patients with atrial fibrillation (AF), according to a study presented at EHRA 2019.
Use of uninterrupted edoxaban during catheter ablation for atrial fibrillation (AF) shows comparable safety and efficacy as uninterrupted vitamin K antagonists (VKAs), according to the ELIMINATE-AF trial presented at EHRA 2019.
Patients on the anticoagulant drug edoxaban could safely continue their treatment while undergoing certain procedures, with a low incidence of bleeding and cardiovascular events reported in the prospective EMIT AF/VTE* study.
Treatment with the oral 11β-hydroxylase inhibitor osilodrostat continues to maintain a normalized mean urinary free cortisol (mUFC) in patients with Cushing’s Disease (CD) in a phase III trial presented at ENDO 2019.
Long-term testosterone therapy in obese men with hypogonadism led to sustained weight loss and improvements in multiple anthropometric parameters, according to an observational study presented at ENDO 2019.
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