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Top Medical News
Women of South Asian, Middle Eastern and Sub-Saharan African origin appear to have the highest risk of iron deficiency (ID) and anaemia, according to a study, adding that ID prevalence significantly differs depending on the iron indicator used.
Breast cancer patients experience consistent levels of anxiety and depression within the first year after surgery, a new study has found. Moreover, pessimism at baseline predicts changes in both anxiety and depression 5 years after diagnosis.
Dietary intake of the fatty acids (FAs) omega-3 and omega-6 was associated with opposing effects in severity of childhood asthma and susceptibility to environmental pollutants, suggests the AsthmaDIET study.
Habitual consumption of fish and long-chain n–3 polyunsaturated fatty acids (PUFAs) may reduce the genetic association with long-term weight gain, according to a recent study.
A deletion in the angiotensin-converting enzyme (ACE-D) gene increases the risk of acute kidney injury (AKI) after cardiac surgery in Southeast Asians, according to a recent Singapore study. On the other hand, the 572C allele of the interleukin-6 (IL-6) gene appears to exert a protective effect.
The risk of self-harm appears to be extraordinarily high in the immediate period following discharge from psychiatric hospitalization, particularly during the first week and first month, a study has found.
A decline in activities of daily living (ADL) appears to predict being hospitalized for heart failure (HF) and death in HF patients, a recent study suggests.
Special Reports
In conjunction with the launch of Abilify Maintena® in Malaysia, Lundbeck Malaysia convened a symposium which saw distinguished speakers discussing the role of long-acting injectable (LAI) antipsychotics, such as aripiprazole (Abilify Maintena®, Lundbeck), in the management of schizophrenia, particularly in the early course of schizophrenia (ie, first-episode schizophrenia, FES).
Dapagliflozin 5 mg and 10 mg FC tab
Sunscreen products commonly contain only filters against ultraviolet (UV) radiation. At a recentdinner symposium organized by Eucerin, Dr Rungsima Wanitphakdeedecha discussed whythis is insufficient and what is required for effective protection against the damaging effects ofsunlight on the skin
At the Eisai-sponsored tea symposium during the 27th Malaysian Urological Conference at Shangri-La Kuala Lumpur, Professor Osamu Yokoyama highlighted the advantages of silodosin (Urief®, Eisai Inc.) in relieving lower urinary tract symptoms associated with benign prostate hyperplasia.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat osteoarthritis and rheumatoid arthritis to reduce joint pain and improve joint function. Dr Sazzli Kasim provides his viewpoint on how the current understanding on cardiovascular safety of NSAIDs should be taken into account when determining optimal analgesic strategies for patients with arthritis.
In March 2018, sublingual fentanyl citrate (SLF; Abstral®, Menarini) was made available in Malaysia. SLF is a rapid-onset opioid (ROO) indicated for the management of breakthrough cancer pain (BTcP) episodes in patients that are opioid-tolerant. In July 2018, Menarini organized an expert meeting, aptly named Malaysian Collaborative Meeting of Pain Specialists to Improve Oncology Management (MY-COMPASSION), comprising of key figures in anaesthesiology, palliative care and oncology to discuss current insights into local BTcP management. Below are highlights from the meeting.
Comprehensive genomic profiling (CGP) has emerged as a key driving force behind personalized cancer care. With the wealth of data available with CGP, medical oncologists now have in their armamentarium a tool that could enable them to provide patients with the optimum treatment. At a Roche Foundation Medicine-sponsored symposium held at the 2018 European Society of Medical Oncology (ESMO) Congress in Munich, Germany, a panel of experts reviewed key data on CGP, with a focus on the treatment of advanced cancers.
Conference Reports
A contraceptive vaginal system (Annovera) releasing a combination of segesterone acetate and ethinyl estradiol (SA/EE) effectively inhibits ovulation up to a year even at low systemic levels of SA, reports a review study presented at ENDO 2019.
Individuals with poorly controlled type 2 diabetes (T2D) had greater HbA1c reductions and weight loss when a 7 or 14 mg/day dose of the GLP-1* receptor agonist semaglutide rather than sitagliptin was added to their background diabetic medications, results of the phase IIIa PIONEER 3** trial showed.
Systolic blood pressure (SBP) above 129 mm Hg was associated with an increased risk of dementia in middle-aged patients with atrial fibrillation (AF), according to a study presented at EHRA 2019.
Use of uninterrupted edoxaban during catheter ablation for atrial fibrillation (AF) shows comparable safety and efficacy as uninterrupted vitamin K antagonists (VKAs), according to the ELIMINATE-AF trial presented at EHRA 2019.
Patients on the anticoagulant drug edoxaban could safely continue their treatment while undergoing certain procedures, with a low incidence of bleeding and cardiovascular events reported in the prospective EMIT AF/VTE* study.
Treatment with the oral 11β-hydroxylase inhibitor osilodrostat continues to maintain a normalized mean urinary free cortisol (mUFC) in patients with Cushing’s Disease (CD) in a phase III trial presented at ENDO 2019.
Long-term testosterone therapy in obese men with hypogonadism led to sustained weight loss and improvements in multiple anthropometric parameters, according to an observational study presented at ENDO 2019.
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