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Top Medical News
Hepatocellular carcinoma patients who receive liver transplant from a live donor enjoy better survival than those who need to wait for a deceased donor graft, a new study has found.
The monoclonal antibody abrilumab is effective for treating moderate-to-severe ulcerative colitis, promoting remission, clinical response and mucosal healing, a recent study has found.
Increased long-term blood pressure (BP) variability is a predictor of chronic kidney disease (CKD) in patients with type 2 diabetes and hypertension, suggests a recent study.
Total thyroidectomy, but not medical therapy, improves health-related quality of life and fatigue in patients with Hashimoto disease, a chronic autoimmune thyroiditis, a Norway study has shown.
Regardless of the burden of cardiovascular disease (CVD) risk factors, higher fitness improves survival in elderly adults, according to a new study presented at the recently concluded 68th Annual Scientific Session of the American College of Cardiology (ACC 2019).
Watching too much television and skipping breakfast promote cholesterol plaque buildup in the arteries of the heart. On the other hand, hitting the off button on the TV, leaving the couch and eating a high-energy breakfast act protectively against atherosclerosis and offer substantial benefits in terms of heart health, according to data from the Corinthia epidemiological study presented at the American College of Cardiology Annual Scientific Session 2019.
Sleeping for short hours may have unfavourable effects on blood pressure, with a recent study showing that individuals with short sleep duration nightly are at higher risk of hypertension compared with those who get longer hours.
Special Reports
At the Eisai-sponsored tea symposium during the 27th Malaysian Urological Conference at Shangri-La Kuala Lumpur, Professor Osamu Yokoyama highlighted the advantages of silodosin (Urief®, Eisai Inc.) in relieving lower urinary tract symptoms associated with benign prostate hyperplasia.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat osteoarthritis and rheumatoid arthritis to reduce joint pain and improve joint function. Dr Sazzli Kasim provides his viewpoint on how the current understanding on cardiovascular safety of NSAIDs should be taken into account when determining optimal analgesic strategies for patients with arthritis.
In March 2018, sublingual fentanyl citrate (SLF; Abstral®, Menarini) was made available in Malaysia. SLF is a rapid-onset opioid (ROO) indicated for the management of breakthrough cancer pain (BTcP) episodes in patients that are opioid-tolerant. In July 2018, Menarini organized an expert meeting, aptly named Malaysian Collaborative Meeting of Pain Specialists to Improve Oncology Management (MY-COMPASSION), comprising of key figures in anaesthesiology, palliative care and oncology to discuss current insights into local BTcP management. Below are highlights from the meeting.
Comprehensive genomic profiling (CGP) has emerged as a key driving force behind personalized cancer care. With the wealth of data available with CGP, medical oncologists now have in their armamentarium a tool that could enable them to provide patients with the optimum treatment. At a Roche Foundation Medicine-sponsored symposium held at the 2018 European Society of Medical Oncology (ESMO) Congress in Munich, Germany, a panel of experts reviewed key data on CGP, with a focus on the treatment of advanced cancers.
In an era of antimicrobial resistance, newer agents are urgently needed. Ceftaroline, a broad spectrum cephalosporin approved for the treatment of community-acquired pneumonia (CAP) and complicated skin and soft tissue infections (cSSTI) is a step forward towards addressing this need. MIMS Anti-Infectives interviewed Dr Asok Kurup, an infectious disease physician practising at the Mount Elizabeth Medical Centre in Singapore, to provide some insights into the role of ceftaroline for the treatment of these conditions.
In conjunction with the launch of QV Intensive with Ceramides (Ego Pharm), the important role of ceramides in themanagement of atopic dermatitis (AD) was highlighted by two distinguished speakers, Dr Agnes Heng of KPJ and Pantai Hospital Ipoh, as well as Dr Fabrizio Spada of Ego Pharmaceuticals, Australia.
At the recent 34th Annual Congress of the Malaysian Society of Nephrology, Dr Kyriaki Stamatelou reviewed the role of alfacalcidol (One-Alpha®; LEO Pharma) – a vitamin D analogue – in the prevention and management of secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD).
Conference Reports
Use of a smartphone app to monitor blood pressure (BP) remotely, get tips on healthful living and connect with a health coach results in a significant decline in BP within 6 weeks among individuals with both type 2 diabetes (T2D) and uncontrolled hypertension, according to a study presented at the American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).
Not many reproductive-aged women have had their lipid levels checked, with more than three-quarters of those attending a postpartum visit not having undergone lipid screening. This underscores peripartum period as an important window of opportunity for screening, according to a study presented at the American College of Cardiology Annual Scientific Session 2019.
Good history taking coupled with pattern recognition to identify specific subtypes of dementia, and along with prudent use of functional and pathological imaging, are vital in the diagnostic approach for dementia.
High-intensity interval training (HIIT) is better than moderate-intensity continuous training at cutting abdominal fat distribution and total body fat and at increasing lean mass, according to a new study presented at the recently concluded American College of Cardiology's 68th Annual Scientific Session.
Long-term results of the POET* trial have suggested that patients with left-sided infective endocarditis (IE) could safely switch from conventional intravenous (IV) antibiotics to oral antibiotics, with oral antibiotics associated with a reduced mortality risk.
Extensive coronary artery calcium (CAC ≥1,000) in patients corresponds to a very high-risk phenotype that is associated with mortality outcomes equal to high-risk patients treated for secondary prevention of cardiovascular disease (CVD), reports a study presented at the American College of Cardiology (ACC) Annual Scientific Sessions 2019.
Following a low-carbohydrate diet to shed excess pounds may be bad for the heart, such that individuals consuming low levels of carbohydrates are at increased risk of developing atrial fibrillation, according to a study presented at the American College of Cardiology Annual Scientific Session 2019.
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