Top Medical News
Pearl Toh, 5 hours ago
Intraoperative remifentanil infusion was associated with increased requirement for opioids in post-anaesthesia care unit (PACU) and delayed discharge from PACU compared with intraoperative morphine or fentanyl in patients undergoing head and neck surgery lasting ≥2 hours, according to a local observational study.
6 hours ago
Distress and unmet needs of cancer patients are correlated with higher utilization rates of psychosocial services during the first 12 months following symptom assessment, a recent study has found.
8 hours ago
Flares are common in rheumatoid arthritis (RA) patients with low disease activity (LDA), according to a study. Flares also correlate with worse disease activity, quality of life and radiographic progression.
9 hours ago
There is only a slight improvement in prostate cancer detection rate and Gleason grading as a result of obtaining more than one biopsy core per magnetic resonance imaging (MRI) lesion, a study has shown.
10 hours ago
Ranolazine offers a cost-effective addition to standard-of-care (SoC), resulting in improved quality-adjusted life years (QALYs) in type 2 diabetes (T2D) patients with stable but symptomatic angina, reports a recent US study.
11 hours ago
Resistance of Helicobacter pylori to common antimicrobials is at an alarming level globally, with almost all WHO regions showing at least 15 percent resistance to clarithromycin, metronidazole and levofloxacin, a recent study has found.
Pearl Toh, Yesterday
Lipid-lowering with ezetimibe monotherapy was effective for the primary prevention of atherosclerotic cardiovascular (CV) events in middle- to high-risk elderly Japanese patients with hypercholesterolaemia, according to the EWTOPIA75* study presented at AHA 2018 Scientific Sessions.
Special Reports
01 Nov 2018
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.
Dr. Robert Giugliano, Prof. Ulrich Laufs, Prof. Gaetano De Ferrari, Prof. Naveed Sattar, 11 Oct 2018

The FOURIER trial previously demonstrated that adding the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab to background statin therapy lowered LDL-cholesterol (LDL-C) below target levels and significantly reduced the risks of cardiovascular (CV) events in patients with atherosclerotic cardiovascular disease (ASCVD). At the European Society of Cardiology (ESC) Congress 2018 in Munich, Germany, experts reiterated how evolocumab helps lower LDL-C levels and reduces CV events even in patients with various comorbidities.

02 Oct 2018
Type 2 diabetes mellitus (T2DM) is associated with substantial risks of cardiovascular disease (CVD) risk and overall mortality, despite the advances in treatment options.1 Recently, MIMS Doctor spoke to Dato’ Sri Dr Azhari Rosman, a Senior Consultant Cardiologist at the National Heart Institute, to provide an update on the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in managing CV risk associated with T2DM, and discuss the results of the recently published Comparative Effectiveness of Cardiovascular Outcomes (CVD-REAL) 2 study. Here are the highlights from the interview.
27 Sep 2018
PRALUENT – alirocumab 75 mg/mL and 150 mg/mL soln for inj - sanofi-aventis
27 Sep 2018
VICTOZA – Liraglutide 6 mg/mL soln for inj - Novo Nordisk
01 Sep 2018
The “Stay healthy: You call the shots” meeting, hosted by Sanofi Pasteur, was held at Thistle Port Dickson. During the meeting, Dr Ho Bee Kiau, Dr Leong Chee Loon and Dr Salehuddin Samsudin shared their insights into the role of influenza vaccination in reducing antimicrobial resistance (AMR), complications in high-risk patient populations, and dispelling vaccination myths among patients.
01 Sep 2018
Ischaemic heart disease was the principal cause of death in Malaysia in 2016, and ST-segment elevation myocardial infarction (STEMI) is noted as the deadliest clinical presentation of Acute Coronary Syndrome. At the National Heart Association of Malaysia’s 2018 Annual Scientific Meeting, Professor Dr Wan Azman Wan Ahmad shared his insights into the management of STEMI in Malaysia, highlighting the implications of the recent TREAT trial.
Conference Reports
Pearl Toh, 16 Nov 2018
Lipid-lowering with ezetimibe monotherapy was effective for the primary prevention of atherosclerotic cardiovascular (CV) events in middle- to high-risk elderly Japanese patients with hypercholesterolaemia, according to the EWTOPIA75* study presented at AHA 2018 Scientific Sessions.
Audrey Abella, 16 Nov 2018
Supplementation with either omega-3 fatty acids (ie, fish oil) or vitamin D did not reduce the incidence of major cardiovascular (CV) events (ie, composite of myocardial infarction [MI], stroke, and CV death) or total invasive cancer, according to the VITAL* trial presented at AHA 2018.
Elaine Soliven, 15 Nov 2018
The administration of sacubitril-valsartan, an angiotensin receptor-neprilysin inhibitor, during hospitalization significantly reduces the N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels among patients with acute decompensated heart failure (ADHF) and reduced ejection fraction compared with enalapril, according to the PIONEER-HF* trial.
Elvira Manzano, 11 Nov 2018
Low-dose methotrexate, which is approved for the treatment of rheumatoid arthritis (RA) and other autoimmune disorders, has shown unexpectedly disappointing results in preventing cardiovascular (CV) events among patients with a prior myocardial infarction (MI) or multivessel coronary disease, according to CIRT*, potentially ruling out what could be an affordable option for treating inflammation related to atherosclerosis.
Roshini Claire Anthony, 09 Nov 2018

Patients with advanced, unresectable melanoma may derive overall survival (OS) and progression-free survival (PFS) benefits when treated with a nivolumab plus ipilimumab combination or nivolumab alone, according to 4-year results of the phase III CheckMate 067* trial presented at ESMO 2018.

Audrey Abella, 09 Nov 2018
The drug combination comprising gemcitabine, cisplatin, and S-1 (GCS) led to significant survival benefits compared with the standard dual chemotherapy regimen of gemcitabine and cisplatin (GC) among patients with advanced biliary tract* cancer (BTC), according to results of the KHB01401–MITSUBA** trial presented at ESMO 2018.
Pearl Toh, 05 Nov 2018
Taking a high daily dose multi-strain probiotic may help reduce incidence of mild-to-moderate chemotherapy-induced diarrhoea (CID), a side effect commonly experienced by cancer patients, suggests a randomized study presented at ESMO 2018.
CME Modules
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