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Top Medical News
Diabetes mellitus appears to be an independent risk factor for seizures in elderly individuals, with the risk of seizures increasing with the number of comorbidities, a study from Italy has found.
The diagnostic accuracy of HbA1c for diabetes decreases with age, with declining red blood cell (RBC) counts mediating this effect, reveals a new study on Chinese middle-aged and elderly adults.
Greater exposure to total volatile organic compounds (TVOCs) appears to have an adverse effect on early postnatal growth, according to a study.
Ertugliflozin 15 mg once daily is noninferior to the sulphonylurea glimepiride in HbA1c reduction over 52 weeks in patients with type 2 diabetes (T2D) who are inadequately controlled on metformin, according to the VERTIS SU* trial presented at the EASD 2017 in Lisbon, Portugal.
Obesity appears to decrease the risk of all-cause death in patients receiving statins after acute myocardial infarction, a recent study from Korea has shown.
Higher body fat content at baseline in patients with ankylosing spondylitis (AS) is likely to weaken response to treatment with tumour necrosis factor-α (TNF-α) blockers, measured by the Ankylosing Spondylitis Disease Activity Score containing C-reactive protein (ASDAS-CRP) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), suggests a recent study.
Among ageing adult congenital heart disease (ACHD) patients, traditional atherosclerotic risk factors are associated with coronary artery disease (CAD), while ischaemic stroke is related to factors suggesting a cardioembolic aetiology, a multicentre case–control study has found.
Special Reports
Agents such as beta-blockers and calcium antagonists have been the cornerstone of treatment for stable angina for some time. However, new options are emerging for patients who remain inadequately controlled on conventional therapies. At a recent Menarini-sponsored symposium held during the APSC Congress 2017 in Singapore, three experts discussed the current treatment landscape, as well as changing paradigms and new effective options for patients with symptomatic angina.
Experience-sharing interview: Managing a case of urinary incontinence
The prevalence of atopic dermatitis (AD) in industrialized countries has increased exponentially over the past three decades, currently affecting 15 to 30% of children and up to 10% of adults.1 At the recent official launch event of pimecrolimus (Elidel®, Meda Healthcare Sdn. Bhd.) held at Le Méridien Kuala Lumpur, Professor Thomas Luger provided insights on the pathophysiology of AD and the role of topical calcineurin inhibitors (TCIs) in the management of AD.
In this edition of MIMS Infectious Disease, we bring you selected updates in the HIV treatment, and also symposium highlights from the relaunch of Tivicay (dolutegravir; GSK, ViiV Healthcare).
Persons with underlying medical conditions are at higher risk of influenza-associated hospitalization.
Tiotropium/olodaterol (Spiolto® Respimat®, Boehringer Inghelheim) is the latest dual bronchodilator therapy available in Malaysia for COPD.
Chronic obstructive pulmonary disease (COPD) is the fourth cause of global mortality, with experts predicting a potential future rise in the prevalence rates of COPD.
Conference Reports
Ertugliflozin 15 mg once daily is noninferior to the sulphonylurea glimepiride in HbA1c reduction over 52 weeks in patients with type 2 diabetes (T2D) who are inadequately controlled on metformin, according to the VERTIS SU* trial presented at the EASD 2017 in Lisbon, Portugal.
The addition of the glucagon-like peptide-1 analogue semaglutide to standard of care resulted in sustained reduction in weight and waist circumference in individuals with type 2 diabetes (T2D) with high cardiovascular risk, according to the phase III SUSTAIN 6* trial presented at EASD 2017.
Intranasal delivery of dry powder glucagon in paediatric type 1 diabetes (T1D) patients with moderate to severe hypoglycaemia appears to induce recovery over half an hour, with the rise in blood glucose occurring within 15 minutes, according to a study presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017).
The addition of the sodium-glucose cotransporters 1 and 2 (SGLT1 and SGLT2) inhibitor sotagliflozin improved glycated haemoglobin levels, systolic blood pressure, and weight in patients with type 1 diabetes (T1D) on insulin therapy, according to findings of the InTandem3* trial presented at EASD 2017.
Use of continuous glucose monitoring (CGM) in the management of diabetes may lead to performance of fewer self-monitoring blood glucose tests, without any deleterious impact on glycaemic control, according to a study presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017).
A gluten-free diet (GFD) may help delay the increase of insulin dose in children with newly diagnosed type 1 diabetes mellitus (T1DM), according to a study presented at EASD 2017.
Increasing the frequency of meals (six-meal pattern), compared with a three-meal pattern, improves glucose metabolism and satiety in obese patients with impaired glucose tolerance (IGT) or type 2 diabetes mellitus (T2DM), according to a 24-week weight maintenance study presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017) in Lisbon, Portugal.
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