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Top Medical News
43 minutes ago
Ulcerative colitis (UC) patients who satisfy a more rigorous definition of disease remission are less likely to relapse, reports a new meta-analysis.
43 minutes ago
High testosterone levels carry a twofold increased risk of progression to nonalcoholic steatohepatitis (NASH) and fibrosis, as well as a higher likelihood of abdominal obesity, in young women with nonalcoholic fatty liver disease (NAFLD), a study has found.
2 hours ago
There appears to be inconclusive evidence on the potential of the novel class of glucose-lowering drugs, namely sodium glucose-linked cotransporter 2 (SGLT2) inhibitors, in stroke therapy, according to the results of a systematic review. This is because few animal studies are available, and some of the clinical studies evaluate combinations of drug treatments of SGLT2 and other drugs related to diabetes treatment.
Rachel Soon, 8 hours ago

More timely diagnosis and treatment for peripheral artery disease (PAD) can significantly reduce the need for late-stage amputations, say experts.

Roshini Claire Anthony, 14 hours ago

At least one-third of antibiotic prescriptions for suspected pneumonia in hospitalized patients may be unnecessary, highlighting the importance of antibiotic stewardship strategies, a US study showed.

14 hours ago
High-dose atropine helps slow the progression of high myopia in kids with or at risk of developing the condition, a recent study has found.
Pearl Toh, 17 hours ago
Olaparib, a PARP* inhibitor used to treat ovarian and breast cancer, also extends overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC) harbouring at least one mutation in BRCA1, BRCA2, or ATM, according to final report of the PROfound** study presented at ESMO 2020.
Special Reports
26 Oct 2020

An estimated 463 million adults – about one in 11 – had diabetes in 2019. These numbers are expected to rise to 700 million by 2045. Worse, one in two people are undiagnosed. [https://www.idf.org/, accessed 19 October 2020]

Pearl Toh, 22 Oct 2020
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
16 Oct 2020
Antihistamines (AHs) are the mainstay of treatment for allergic rhinitis (AR) in primary care. Nevertheless, choosing the best therapy from a wide selection of AHs can be challenging. At a virtual forum hosted by Bayer Co. (Malaysia), two experts discussed the role of patient profiling as a tool to guide the choice of AHs for AR.
Audrey Abella, 14 Oct 2020
Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Pearl Toh, 16 Sep 2020
Mepolizumab, a first-in-class anti-IL-5* antibody, effectively prevents asthma exacerbations in patients with severe eosinophilic asthma (SEA), according to a presentation at the ERS 2020 Congress.
16 Sep 2020
XOFLUZA – Baloxavir marboxil 20 mg and 40 mg FC tab
Conference Reports
Pearl Toh, 27 Oct 2020
Olaparib, a PARP* inhibitor used to treat ovarian and breast cancer, also extends overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC) harbouring at least one mutation in BRCA1, BRCA2, or ATM, according to final report of the PROfound** study presented at ESMO 2020.
Elaine Soliven, 27 Oct 2020
Ultra rapid lispro (URLi) was noninferior to lispro in reducing HbA1c levels in adults with type 1 diabetes (T1D), according to the PRONTO-Pump-2* study presented at EASD 2020.
Roshini Claire Anthony, 23 Oct 2020

Durvalumab with or without tremelimumab in the first-line setting does not improve overall survival (OS) over standard-of-care (SoC) chemotherapy in patients with unresectable, locally advanced or metastatic urothelial carcinoma, according to the phase III DANUBE trial.

Roshini Claire Anthony, 21 Oct 2020

NT-814, an oral, non-hormonal dual neurokinin 1,3 receptor antagonist may reduce the frequency of hot flashes, while improving quality of life (QoL) and sleep in postmenopausal women, according to results of the phase IIb SWITCH-1 trial presented at NAMS 2020.

Roshini Claire Anthony, 20 Oct 2020

The increased risk of mortality among patients with cancer diagnosed with COVID-19 may be due to their older age and presence of comorbidities, according to a study presented at ECCVID 2020.

Roshini Claire Anthony, 19 Oct 2020

Women who experience two or more moderate or severe menopausal symptoms may have an elevated risk of cardiovascular disease (CVD) or strokes, according to a study presented at NAMS 2020.

Pearl Toh, 17 Oct 2020
A head-to-head study comparing five serological assays for SARS-CoV-2 antibodies showed that a commercial immunoassay by Siemens and a novel ELISA* test developed by the University of Oxford could achieve the desired sensitivity and specificity without further optimization — providing reassurance for their use.
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