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Multidisciplinary
Top Medical News
UNR844, an investigational topical lipoic acid choline ester eye drop, is safe and well-tolerated for the treatment of presbyopia and yields improvements in distance-corrected near visual acuity, a recent study has found.
The SGLT2i* canagliflozin significantly improves symptoms and quality of life (QoL) early on during treatment in people with heart failure (HF) due to either reduced or preserved ejection fraction (rEF or pEF), regardless of whether they have type 2 diabetes (T2D), according to the CHIEF-HF** study presented at AHA 2021.
Undergoing a surgery to remove the gallbladder appears to contribute to an increased risk of developing Parkinson’s disease (PD) in men, a study has found.
Caesarean delivery appears to obstruct placental transfusion from mother to neonate and lessens iron stores at birth, a recent study suggests.
Hospitalization for diabetes-related foot ulcerations (DFU) seems to result in bilateral decreases in total hip and femoral bone mineral density (BMD), a recent study has found.
An assay that detects DNA associated with bacterial vaginosis, vulvovaginal candidiasis, and Trichomonas vaginalis helps women get an accurate diagnosis, which in turn facilitates appropriate and timely treatment, according to a study.
Regular use of proton pump inhibitors (PPI) seems to slightly aggravate the risk of inflammatory bowel disease, a recent study has found.
Special Reports
Esflurbiprofen 40 mg transdermal patch
Upadacitinib 15 mg XR-FC tab
It has been estimated that diabetes – a chronic metabolic disorder resulting in hyperglycaemia – affects 422 million adults globally.1 In 2019, the disease caused 1.5 million deaths worldwide and the number of people with diabetes is expected to reach 642 million by 2040.
During the Guardians for Health Summit 2021 supported by Boehringer Ingelheim, several distinguished speakers shared their insights into the importance of type 2 diabetes (T2D) guideline adherence and patient empowerment, as well as the impact of clinical inertia on the burden of cardiorenal metabolic diseases.
Romosozumab 105 mg/1.17 mL soln for inj
Heart failure with preserved
ejection fraction (HFpEF) represents a significant unmet medical need. The
EMPEROR-Preserved trial aimed to assess the impact of empagliflozin on
cardiovascular outcomes in patients with HFpEF. On 27 August 2021, during the
hotline session of the 2021 ESC Virtual Congress, the main results of the
EMPEROR-Preserved trial were presented by Professor Stefan Anker, principal
investigator of the study, and heart failure specialist at Charité Berlin,
Germany.
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice, affecting millions of people globally. Stroke is one of its devastating complications, with the risk steeply increasing with advancing age. Additionally, AF is associated with more than a tripling of the risk of systemic embolic (SE) events. [J Am Heart Assoc 2020;9:e016724]
Conference Reports
Non-overweight patients with non-alcoholic fatty liver disease (NAFLD) have an elevated risk of all-cause mortality following liver transplant and are also more likely to be removed from the liver transplant waitlist compared with obese/overweight patients, according to a study presented at The Liver Meeting Digital Experience™.
Treatment with inclisiran consistently reduced low-density lipoprotein cholesterol (LDL-C) levels in patients with, or at high risk of, atherosclerotic cardiovascular disease (ASCVD), regardless of glycaemic status, based on a pooled analysis of the ORION-10* and ORION-11** studies presented at AHA 2021.
Postoperative treatment with the oral factor XIa inhibitor milvexian could help prevent the incidence of venous thromboembolism (VTE) in patients undergoing elective knee arthroplasty, according to results of a phase II trial presented at AHA 2021.
Two-dose hep-B vaccine more seroprotective than three-dose regimen in chronic liver disease patients
In a pooled post hoc analysis of three phase III trials, a novel two-dose hepatitis B (hep-B) vaccine regimen trumped the traditional three-dose regimen in inducing seroprotection in patients with chronic liver disease (CLD).
The pleuromutilin inhibitor lefamulin shows similarly high efficacy as moxifloxacin (a standard fluoroquinolone therapy for clearing bacterial pneumonia) regardless of whether it was for unilobar or multilobar pneumonia, according to pooled data of the LEAP* 1 and 2 studies.
Higher sodium and lower potassium intake, measured through repeat 24-hour urine samples, are tied to an elevated risk of cardiovascular (CV) events, according to a study presented at AHA 2021.
The addition of ezetimibe to a statin led to reductions in low-density lipoprotein-cholesterol (LDL-C) in patients who have been stabilized after the presentation of an acute coronary syndrome (ACS), according to data presented at AHA 2021.
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