The interleukin-1 beta (IL-1β) inhibitor canakinumab did not prevent the progression from pre-diabetes to diabetes in patients with prior myocardial infarction (MI), according to results of the CANTOS* trial.
Recent developments on CDK 4/6 trials in patients with oestrogen receptor-positive metastatic breast cancers (ER+ MBC) were reviewed at ESMO and ASCO 2017.
Individuals with type 2 diabetes (T2D) who initiate therapy with sodium glucose cotransporter-2 (SGLT-2) inhibitors have lower risks of all-cause death and cardiovascular (CV) outcomes, specifically myocardial infarction (MI) and stroke, compared with those who initiate other glucose-lowering therapies, according to results from the CVD-REAL* 2 study.
Patients with acute coronary syndrome (ACS) who received a 6-month course of dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI) fared similarly to those who received the standard ≥12-month DAPT course with regards to incidence of major adverse cardiovascular and cerebrovascular events 18 months post-procedure, according to results from the SMART-DATE* trial. However, a higher incidence of myocardial infarction (MI) with 6-month DAPT precludes it from replacing the standard course.