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Multidisciplinary
Top Medical News
In patients with diabetes, plasma heparin cofactor II (HCII) activity is inversely associated with glomerular injury and may serve as a biomarker for early-stage diabetic kidney disease, a new study has found.
Aquatic-based plyometric exercises are safe and improve muscle strength, fatigue, and functional ability in patients with juvenile dermatomyositis, as shown in a study.
A traditional Japanese diet (TJD) appears to reduce breast cancer incidence and mortality, suggest the results of a longitudinal analysis.
The inclusion of a clinical oncology pharmacist into an ambulatory care pharmacy in paediatric haematology–oncology and transplant clinic results in reduced adverse events and fewer readmission into the hospital, a study has shown.
Hospital readmission due to medications are common, especially in older patients, a recent study has found. Comorbid, highly medicated patients who live alone are also at excess risk of medication-related readmissions.
An elevated ratio between apolipoproteins B to A-1 (apoB/apoA-1) correlates with a higher incidence of aortic stenosis regardless of previous major adverse cardiovascular events, especially in the elderly and in women, a recent study has found.
As recently diagnosed men wait for their prostate cancer surgery, participating in a community-based, preoperative exercise programme may help improve their overall wellbeing and quality of life, a recent study has found.
Special Reports
Ceftaroline fosamil 600 mg powder for infusion
Perindopril arginine 3.5 mg,
Amlodipine besilate 2.5 mg tab
Amlodipine besilate 2.5 mg tab
Furfuryl Palmitate
Letermovir 240 mg film-coated tab and infusion conc
In a webinar held on 27 March 2021, paediatric
endocrinology nurses Karen Blair,
Kate Davies, and Siti Zarina Yaakop shared
insights and clinical experience based
on their frontline roles in caring for patients
with central precocious puberty (CPP)
and supporting their family members.
Intravitreal injections with anti-vascular endothelial growth factor (VEGF) agents are associated with significant treatment burden for patients with diabetic macular oedema (DME) and neovascular age-related macular degeneration (nAMD). At the Angiogenesis, Exudation, and Degeneration 2021 Virtual Congress, Dr Karl Csaky of Retina Foundation of the Southwest, Dallas, Texas, US, Dr Charles Wykoff of Retina Consultants of Texas, Houston, Texas, US, and Dr Jeffrey Heier of Ophthalmic Consultants of Boston, Boston, Massachusetts, US, presented results of four phase III trials that compared the efficacy and safety of the investigational bispecific antibody, faricimab, administered at up to Q16W dosing intervals, vs the decoy VEGF-A/placental growth factor (PIGF) receptor aflibercept at Q8W dosing intervals, in patients with retinal vascular diseases.
Intensive care unit (ICU) patients are at risk of developing serious infections with multidrug-resistant organisms (MDROs), which require appropriate and adequate antibiotic coverage. Early empirical coverage is pivotal in saving patients’ lives. At a recent webinar co-organized by the Society of Infectious Disease (Singapore) and Pfizer, renowned Professor David Paterson, Professor of Medicine and Director, The University of Queensland Centre for Clinical Research, and Consultant Infectious Diseases Physician, Royal Brisbane and Women’s Hospital, Brisbane, Australia, discussed the role of newer antimicrobial agents, including ceftazidime-avibactam (Zavicefta) in the management of MDROs in the ICU. Dr Wong Sin Yew, Infectious Disease Physician at Gleneagles Medical Centre and Mount Elizabeth Novena Specialist Centre, Singapore, chaired the event.
Conference Reports
Certain therapies used for rheumatic diseases, including rituximab, are associated with worse outcomes for COVID-19 and reduced immune response after COVID-19 vaccination in patients with rheumatic diseases, according to two studies presented at the virtual EULAR 2021 Congress.
Treatment with the fully human anti-IL17 monoclonal antibody secukinumab resulted in fewer, and a longer time to, disease flares in children and adolescents with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA), results of the phase III JUNIPERA trial showed.
Once-weekly injection of the GLP-1* agonist semaglutide, on top of endoscopic sleeve gastroplasty (ESG), led to a greater weight loss and better glucose control vs ESG alone in patients with diabetes and excess weight but are not candidates for bariatric surgery, a new study has shown.
Treatment with guselkumab improved response rates in patients with active psoriatic arthritis (PsA) who had inadequate responses to tumour necrosis factor (TNF) inhibitors, according to the COSMOS* study presented at EULAR 2021.
Left atrial appendage occlusion (LAAO) added to usual care led to a reduction in ischaemic stroke or non-cerebral systemic embolism following cardiac surgery among patients with atrial fibrillation (AF), according to results of the LAAOS* III trial.
Data from the EULAR COVID-19 Vaccination (COVAX) Registry showed that available COVID-19 vaccines were safe and well tolerated in patients with rheumatic and musculoskeletal diseases (RMDs).
Treatment with the HMG-CoA reductase inhibitor atorvastatin in critically ill patients with COVID-19 did not significantly reduce the primary composite outcome of venous or arterial thrombosis risk, treatment with extracorporeal membrane oxygenation (ECMO), or mortality vs placebo in the INSPIRATION-S study presented at ACC.21.
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