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Multidisciplinary
Top Medical News
Treatment with the combination of vancomycin and piperacillin/tazobactam (VAN + PTZ) appears to be associated with a greater prevalence of acute kidney injury as compared with VAN or PTZ monotherapy or with the concurrent use of VAN and cefepime or carbapenem, a study reports.
The oral selective JAK*1 inhibitor abrocitinib is superior to dupilumab for relieving itch and achieving skin clearance in people with moderate-to-severe atopic dermatitis (AD), according to results from a head-to-head comparison in the JADE DARE trial presented at EADV 2021.
Combining lenalidomide with R-CHOP* (R2CHOP) yields durable and high rates of treatment response in untreated patient with diffuse large B-cell lymphoma (DLBCL), a recent study has found.
Molecular evidence confirms early renal and vascular damage within the normoalbuminura condition, a recent study has shown.
Hypertension and diabetes are the major predictors of stroke that must be controlled and treated like other global high-risk populations for stroke prevention, according to a prospective study in India.
Higher intake of marine n-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exerts no significant protective effect against incident peripheral artery disease (PAD), a recent study has found.
Posterior-circulation arterial supply and the presence of arteriovenous malformation contribute to an increased risk of perioperative stroke among patients undergoing endovascular therapy, according to a study.
Special Reports
During the recent EMPIRE SUMMIT, Professor Dr Chee Kok Han discussed the importance of an early, patient-centred,multi factorial approach in managing type 2 diabetes mellitus(T2DM). Specifically, Professor Chee highlighted the role ofempagliflozin (Jardiance®, Boehringer Ingelheim) in conferring cardiorenal protection to patients with T2DM.
Psoriasis is characterised by well-circumscribed, erythematous, scaly plaques and can be categorised as eitherlocalised or generalised, depending on the severity of the disease and its impact on patients’ quality of life. The mainstay of treatment for localised disease includes topical therapy with corticosteroids, calcipotriene and coal tar products, while generalised psoriasis may require more advanced forms of treatment like phototherapy and systemic therapy. In this case study, Dr Preamala Gunabalasingam shares her clinical experience treating.2plaque psoriasis with a combined formulation of betamethasone dipropionate and calcipotriol monohydrate in a single spray foam (Enstilar® Foam, LEO Pharma).
Edoxaban 30 mg and 60 mg FC tab
Isavuconazole 100 mg hard cap and 200 mg infusion conc
Cabozantinib 60 mg, 40 mg and 20 mg tab
Sevelamer Carbonate 800 mg FC tab
The FreeStyle Libre™ flash glucose
monitoring system includes a sensor which automatically measures and
continuously stores up to 8 hours of glucose readings, allowing patients to
monitor their glucose levels without the need for painful finger pricks.
Physicians play an important role in reviewing and analysing glucose data
that is available through LibreView to support patient management.
Conference Reports
Mortality following bariatric surgery is rare but more common in men than women, according to a retrospective study from Austria presented at EASD 2021.
Baricitinib, an oral, selective Janus kinase (JAK)1/JAK2 inhibitor, may help improve hair growth in patients with severe alopecia areata, according to results from the phase III BRAVE-AA1 and BRAVE-AA2 trials.
For adults with diabetes, increased blood pressure (BP) at night (reverse dipping) was associated with more than double the risk of death compared with those whose BP dipped as expected at night, according to the longitudinal CHAMP1ON study presented at Hypertension 2021.
In hospitalized COVID-19 patients, treatment with the novel GM-CSF* neutralizing monoclonal antibody lenzilumab led to a significant improvement in survival without invasive mechanical ventilation (SWOV), findings from the phase III LIVE-AIR study suggest.
A single dose of nirsevimab significantly reduced the incidence of medically attended respiratory syncytial virus (RSV)-confirmed lower respiratory tract infections (LRTIs) in healthy infants during their first RSV season, according to the MELODY* study presented at IDWeek 2021.
The osteoporosis drug alendronate halves the risk of developing type 2 diabetes (T2D) in a nationwide, retrospective, case-control study of nearly 700,000 patients from Denmark.
Patients with heart failure and preserved ejection fraction (HFpEF) treated with dapagliflozin experienced improvements in symptoms and physical limitations, according to results of the PRESERVED-HF study presented at HFSA 2021.
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