Multidisciplinary

Physical distancing, face masks key to reducing COVID-19 spread

Roshini Claire Anthony, an hour ago

Physical distancing of ≥1 m and use of face masks and eye protection reduced the risk of COVID-19 transmission in healthcare settings and the community, according to a systematic review and meta-analysis.

Secukinumab gets FDA nod for nr-axSpA

Elvira Manzano, an hour ago

The US FDA has given secukinumab the greenlight for the treatment of active non-radiographic axial spondyloarthritis (nr-axSpA), following its success in the phase III PREVENT trial, the largest ever for a biologic in nr-axSpa.

MiR-34b/c polymorphisms linked to ischaemic stroke risk

3 hours ago

The miR-34b/c rs4938723 polymorphism is positively associated with the risk of ischaemic stroke, reveals a recent study, which indicates that rs4938723 can be used to predict ischaemic stroke or to improve therapy in the future.

DGAT2 a potential therapeutic target for fatty liver?

Audrey Abella, 6 hours ago

Antisense inhibition of DGAT2* – one of two vital enzymes in triglyceride synthesis – may be a favourable strategy for reversing nonalcoholic fatty liver disease (NAFLD), suggesting that targeting this pathway may mitigate NAFLD progression to its more severe form, nonalcoholic steatohepatitis (NASH), a phase II study has shown.

COVID-19 restrictions also suppress other respiratory viruses

Tristan Manalac, 7 hours ago

Public health measures to stop the spread of the coronavirus disease 2019 (COVID-19) may have the unintended benefit of also reducing hospitalizations due to other viral respiratory infections, according to a new study.

Empagliflozin near to us: Insights from its use in Asians

09 Jul 2020

In this fourth issue, join us as we discover the unique biology Asians have with respect to diabetes. Take a closer look at trials evaluating whether empagliflozin’s cardiovascular and renal benefits – as analysed in Asians – are consistent with the overall trial population, and how it addresses unmet needs.

Achieving full functional recovery in MDD: How do we get there?

29 Jun 2020

The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illness. On the first day, eminent local and internationalexperts weighed in on the treatment of major depressive disorder (MDD), including in the elderly and incases of coexisting anxiety.

Early Treatment Intensification in T2DM, The Time is Now

29 Jun 2020

At the Novartis-sponsored VERIFY Soft Launch held at Le Meridien, Kuala Lumpur, two distinguished speakers spoke on the latest updates in glucose-lowering therapy and the benefit of early treatment intensification using combination therapy (ie, vildagliptin/metformin) in the management of T2DM.

HK in CKD: Do diet, HD frequency matter?

Elvira Manzano, 28 Jun 2020

Hyperkalaemia (HK) occurrence and recurrence are frequent in advanced CKD*, creating a perfect storm for cardiovascular events and death, says Professor Juan-Jesus Carrero from the Karolinska Institute, Solna, Sweden, at ERA-EDTA 2020. Given these risks, acutely elevated potassium (K+) should merit clinical attention.

No increased ophthalmic risk with roxadustat treatment in DD CKD-related anaemia

Roshini Claire Anthony, 28 Jun 2020

Roxadustat treatment for anaemia in patients with dialysis-dependent chronic kidney disease (DD CKD) does not come with an increased risk of ophthalmic abnormalities, according to a phase III trial conducted in Japan.

Fertility preservation vital in female cancer survivors

Roshini Claire Anthony, 04 Aug 2020

Female cancer survivors who undergo fertility preservation before cancer treatment often use their stored gametes/embryos. This highlights the effectiveness of pre-cancer fertility preservation, according to a study presented at ESHRE 2020.

Sustained reduction in chronic migraine with onabotulinumtoxinA

Roshini Claire Anthony, 31 Jul 2020

Continuous onabotulinumtoxinA treatment led to a sustained reduction in chronic migraine, according to pooled analysis of the double-blind and open-label phases of the PREEMPT* trial.

One-quarter of calorie intake in children derived from empty calories

Roshini Claire Anthony, 28 Jul 2020

About one-quarter of the calories consumed by children and adolescents may be acquired from empty calories, according to a US-based study presented at Nutrition 2020 Live Online.

EMPRISE reinforces CV benefits of empagliflozin

Elvira Manzano, 28 Jul 2020

The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE⁺ study presented at ADA 2020.

Does spacing pregnancies help women with gestational diabetes?

Elvira Manzano, 28 Jul 2020

Women with a history of gestational diabetes were 50 percent more likely to have a short interval between pregnancies compared to women without the condition, suggests a new study.

No need to fast before cardiac catheterization, suggests study

Pearl Toh, 27 Jul 2020

Having no restriction on oral food intake before cardiac catheterization appears to be as safe as the current standard fasting strategy, according to the CHOW NOW randomized trial presented during the SCAI 2020 Virtual Scientific Sessions.

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