Multidisciplinary

MEFIB bests MAST, FAST for fibrosis detection in NAFLD

17 hours ago

Magnetic resonance elastography (MRE) plus FIB-4 (MEFIB) outperforms both magnetic resonance imaging [MRI]-aspartate aminotransferase (MAST) and FibroScan-AST (FAST) in detecting stage ≥2 fibrosis and at-risk nonalcoholic steatohepatitis (NASH), reveals a study.

Do aortic annular size, valve type affect outcomes after TAVI?

Stephen Padilla, 18 hours ago

Aortic annular size does not appear to have a major impact on valve haemodynamics, prosthesis-patient match (PPM), and mortality following transcatheter aortic valve implantation (TAVI), according to the results of a Singapore study.

Lung fibrosis extent on quantified CT predicts survival in IPF

19 hours ago

The extent of fibrotic abnormality on baseline computed tomography (CT), quantified using data-driven texture analysis (DTA), is predictive of outcomes in patients with idiopathic pulmonary fibrosis (IPF), regardless of pulmonary function, suggests a study.

When dengue fever becomes severe

01 Nov 2022

Dengue has been around for more than a century from the first reported outbreak in 1902,1 with experts advising healthcare professionals (HCPs) from time to time to alert HCPs to the threats of dengue. This is because the dengue virus has been evolving and can cause severe illness especially among vulnerable patients regardless of age. In this fourth interview of a series focused on dengue, Dr Shanthi Ratnam, Consultant Physician and Intensivist, elaborated on the risks, impact and management of dengue, and advocated dengue as a public health priority.

Pregabalin mainstay of treatment in painful diabetic neuropathy

01 Nov 2022

At the recent Novugen Expert Forum, held in Penang, Dr Khaw Chong Hui discussed the prevalence of painful diabetic neuropathy (PDN), role of pregabalin in the treatment of PDN, its place in treatment recommendations of major international pain guidelines and its proven safety and efficacy.

Molecular Pathogenesis and Current Treatment Landscape In MPN, With A Focus On PV

01 Nov 2022

The recent Northern Haematology Update, held in Penang, saw Dr Christopher Ng, Dr Tan Sui Keat and Dr Carol Goh present on various aspects of myeloproliferative neoplasms (MPN)and its management. Dr Christopher Ng, a haematology trainee at Hospital Sultanah Bahiyah, Kedah, discussed the role of mutations as drivers of disease, with a focus on polycythaemiavera (PV) and essential thrombocythaemia (ET).

CT angiography may increase potential recipients of EVT for acute ischaemic stroke

CT angiography may increase potential EVT recipients for acute ischaemic stroke

Roshini Claire Anthony, 27 Nov 2022

Using collateral flow findings, as seen on computed tomographic (CT) angiography, may widen the population who can undergo late endovascular treatment (EVT) for acute ischaemic stroke (AIS), according to findings of the MR CLEAN-LATE trial.

Lower all-cause death, fewer HF events with empagliflozin in acute HF

Roshini Claire Anthony, 25 Nov 2022

Patients hospitalized with acute heart failure (HF) have a reduced risk of subsequent HF events or all-cause mortality if treated with once-daily empagliflozin while in hospital, according to results of the EMPULSE trial presented at HFSA 2022.

Letermovir as good as valganciclovir for CMV prophylaxis

Elaine Soliven, 25 Nov 2022

The novel antiviral letermovir is as good as the current standard of care valganciclovir in preventing cytomegalovirus (CMV) infection in post-kidney transplant patients, but with less toxicity, according to a phase III trial presented at IDWeek 2022.

Post-surgery emergence delirium in kids has no long-term impact

Roshini Claire Anthony, 23 Nov 2022

The use of general anaesthesia (GA) in children undergoing elective surgeries does not lead to long-term deterioration in behavioural outcomes, according to a study presented at Anesthesiology 2022.

TB rates elevated after ART initiation in PLHIV

Roshini Claire Anthony, 21 Nov 2022

People living with HIV (PLHIV) who initiate antiretroviral therapy (ART) are at an increased risk of developing tuberculosis (TB), particularly in the first 3 months after starting ART, according to a study presented at HIV Glasgow 2022.

Low use of CVD prevention strategies in people with HIV

Roshini Claire Anthony, 18 Nov 2022

There is an underutilization of cardiovascular disease (CVD) prevention strategies in people living with HIV (PLHIV) who are at risk of CVD, according to a study presented at HIV Glasgow 2022.