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Top Medical News
Following safe-sleep practices for babies may prevent deaths resulting from unintentional suffocation, with a recent study attributing suffocation deaths to soft beddings, overlay and wedging.
Treatment with abiraterone leads to fewer health-related quality of life (HRQoL) and mental health issues than enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC), a recent study has found.
High neutrophil-to-lymphocyte ratio before radical orchidectomy appears to be predictive of worse outcomes in testicular cancer patients, according to a recent Singapore study.
Mepolizumab as a treatment option for severe eosinophilic asthma has an acceptable long-term safety and efficacy profile, reports a recent study.
A novel three-drug cocktail, PXT3003, reduces disability in patients with Charcot-Marie-Tooth Type 1A disease (CMT1A) along with a favourable safety profile, according to the PLEO-CMT study presented at AAN 2019, providing hope for a rare disease which so far has no cure.
Biweekly treatment with pegloticase yields favourable effects on systolic and diastolic blood pressure as well as mean arterial pressure in gout patients who maintain a persistently low serum urate, and these effects are independent of changes in renal function, according to a posthoc analysis of two trials.
A recent phase Ib study has identified the maximum tolerated dose (MTD) of the combination therapy of entinostat, lapatinib and trastuzumab, which provides acceptable tolerability and antitumour activity in heavily pretreated patients with human epidermal growth factor 2 (HER2)-positive metastatic breast cancer. This also supports a confirmatory trial.
Special Reports
At a Boehringer Ingelheim-sponsored symposium, held in conjunction with the joint 12th International Diabetes Federation Western PacificRegion Congress & 10th Asian Association for the Study of Diabetes Scientific Meeting in Kuala Lumpur, two prominent speakers discussed therapidly evolving treatment landscape for diabetes, focusing on the implications of heart failure (HF) and chronic kidney disease (CKD) in thediabetes continuum.
At a recent Abbott lunch symposium held in conjunction with the joint 12th International Diabetes FederationWestern Pacific Region Congress & 10th Asian Association for the Study of Diabetes Scientific Meeting in KualaLumpur, Professor Shashank R. Joshi extensively discussed the issue of diabetes in obesity and the role of nutritionalintervention in addressing this growing problem.
At the recent 12th IDF-WPR Congress and 10th AASD Scientific Meeting held at Kuala Lumpur Convention Centre, the importance of glycaemic control and the practical management of type 2 diabetes mellitus (T2DM) were highlighted by two international speakers, Dr Sanjay Kalra from India and Professor Jean Claude Mbanya from Cameroon.
Point-of-care ultrasound (POCUS) has become a very popular diagnostic strategy that can be used in a variety of situations. POCUS is defined as a targeted ultrasound examination performed and interpreted by a physician at their patient’s bedside. It is increasingly recognized as a useful extension to physical examination.
At a webinar hosted by Pfizer, leading Malaysian family medicine specialists Professor Chia Yook Chin andProfessor Sherina Mohd Sidik discussed a host of issues commonly encountered in primary care, includingpreventing cardiovascular (CV) disease, pain control in osteoarthritis (OA) and depression management.
In conjunction with the launch of Abilify Maintena® in Malaysia, Lundbeck Malaysia convened a symposium which saw distinguished speakers discussing the role of long-acting injectable (LAI) antipsychotics, such as aripiprazole (Abilify Maintena®, Lundbeck), in the management of schizophrenia, particularly in the early course of schizophrenia (ie, first-episode schizophrenia, FES).
Dapagliflozin 5 mg and 10 mg FC tab
Conference Reports
A novel three-drug cocktail, PXT3003, reduces disability in patients with Charcot-Marie-Tooth Type 1A disease (CMT1A) along with a favourable safety profile, according to the PLEO-CMT study presented at AAN 2019, providing hope for a rare disease which so far has no cure.
The terminal complement inhibitor eculizumab significantly lowered relapse risk in patients with neuromyelitis optical spectrum disorder (NMOSD) who were positive for aquaporin-4 antibodies (AQP4-IgG) compared with placebo, according to the PREVENT* study presented at AAN 2019.
The low uptake of the human papillomavirus (HPV) vaccine in the US and strategies to improve HPV vaccine coverage were highlighted in two studies presented at the Pediatric Academic Societies annual meeting (PAS 2019).
A 10 or 20 mg/kg daily dose of cannabidiol could almost halve the risk of seizures in children with Dravet syndrome, according to the phase III GWPCARE2* study presented at the American Academy of Neurology annual meeting (AAN 2019).
Use of the antihypertensive drug isradipine did not reduce the progression of Parkinson’s disease, according to the STEADY-PD III* study presented at the American Academy of Neurology annual meeting (AAN 2019).
The addition of the first-in-class direct lytic agent exebacase (lysin CF-301) to standard-of-care (SOC) antibiotics demonstrated efficacy against Staphylococcus aureus bacteraemia (SAB), particularly difficult-to-treat methicillin-resistant SA (MRSA), compared with SOC antibiotics alone, according to the results of a phase II trial presented at ECCMID 2019.
A 26-week regimen of liraglutide effectively improved glycaemic control in adolescents with type 2 diabetes (T2D) who had inadequate response to metformin, according to the results of the phase III Ellipse* trial presented as a poster at the recent Pediatric Academic Societies meeting (PAS 2019).
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