Spontaneous miscarriage is the loss of fetus before 20 weeks of gestation or delivery of a fetus weighing <500 g, in the absence of elective medical or surgical measures to terminate pregnancy.
Early loss is considered if it occurred before menstrual week 12 while late loss refers to those that occurred from menstrual week 12-20.
It is also known as spontaneous abortion, spontaneous pregnancy loss or early pregnancy failure.
Administering prophylactic treatment with doxycycline and metronidazole prior to miscarriage surgery does not appear to significantly reduce the risk of pelvic infection, as defined by broad criteria, according to the results of a trial.
Miscarriage or ectopic pregnancy carries a considerable risk of psychological morbidity—post-traumatic stress disorder (PTSD) symptoms, in particular—that persists at least 3 months after pregnancy loss, according to the results of a pilot study.
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Administering intranasal desmopressin to patients with renal dysfunction not requiring haemodialysis reduces bleeding complications during renal biopsies, especially minor complications such as perinephric haematomas, a study has found. However, it may increase the risk of incident hyponatraemia.
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.