Measles, also known as rubeola, is a highly contagious disease caused by the measles virus Morbillivirus.
It is characterized by generalized maculopapular rash, fever, cough, rhinitis and conjunctivitis. Transmission is through respiratory tract or conjunctivae following contact with droplet aerosols.
It is highly communicable from 4 days before the rash up to 4 days after its onset.
The incubation period from exposure to prodrome averages 7-21 days.
The risk of severe outcome in children with measles, while independent of age, increases in the presence of encephalitis or pancreatitis and elevated C-reactive protein (CRP) values, a study has found.
Children under 2 years who received the measles-mumps-rubella-varicella (MMRV) vaccine as a second measles-containing vaccine (MCV) following an MMR vaccine did not have an elevated risk of febrile seizures (FSs), according to an Australian study. The introduction of the MMRV vaccine also increased MCV coverage in Australia.
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Short-term daily consumption or probiotic lozenges containing Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis BB-12 confers benefits for gingival health, as well as reduces the plaque carriage of periodontal pathogens, in adolescent males, a study has shown.
Intraoperative epidural analgesia, perioperative opioid and total dose of volatile agent appear to show some “clinically meaningful associations” with relapse-free survival (RFS) in children with solid organ tumour, particularly in paediatric sarcoma patients, according to a Singapore study. However, no statistically significant association exists between epidural use and an improved RFS.