liver%20abscess
LIVER ABSCESS
Liver abscess may result from peritonitis and bowel leakage via portal circulation, direct spread from biliary disease or from hematogenous seeding.
Classical presentation includes fever, jaundice, and right upper quadrant symptoms (pain, guarding, rocking and rebound tenderness).
Biliary tract disease is the most common cause of bacterial liver abscess.
Most pyogenic liver abscesses are polymicrobial (eg enteric facultative and anaerobic species).
  1. Chung YF, Tan YM, Lui HF, et al. Management of pyogenic liver abscesses – percutaneous or open drainage?. Singapore Med J. 2007 Dec;48(12):1158-1165. http://www.ncbi.nlm.nih.gov. PMID: 18043848
  2. Rahimian J, Wilson T, Oram V, et al. Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis. 2004 Dec;39(11):1654-1659. PMID: 15578367
  3. Johannsen EC, Sifri CD, Madoff LC. Pyogenic liver abscesses. Infect Dis Clin North Am. 2000 Sep;14(3):547-563, vii. PMID: 10987109
  4. Salles JM, Moraes LA, Salles MC. Hepatic amebiasis. Braz J Infect Dis. 2003 Apr;7(2):96-110. PMID: 12959680
  5. Chung RT, Friedman LS. Bacterial, parasitic, and fungal infections of the liver, including liver abscess. In: Feldman M, Friedman LS, Sleisenger MH, eds. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology/diagnosis/management. 8th ed. Philadelphia: Saunders; 2006
  6. MedWormhttp://www.medworm.com/rss/index.php/Gastroenterology/17/http://www.medworm.com/rss/medicalfeeds/specialities/Gastroenterology.xml
  7. Peralta R, Lisgaris M, Salata RA, et al. Liver abscess. eMedicine. http://emedicine.medscape.com. 23 Sep 2008.
  8. Davis J, McDonald M. Pyogenic liver abscess. UpToDate. http://www.uptodate.com. 03 Sep 2013. Accessed 18 Sep 2013.
  9. Ministry of Health Malaysia. National antibiotic guideline 2014, 2nd edition. Pharmaceutical Services Divisions, Ministry of Health Malaysia. http://www.pharmacy.gov.my. Dec 2014. Accessed 16 Jul 2015.
  10. Lardière-Deguelte S, Ragot E, Amroun K, et al. Hepatic abscess: diagnosis and management. J Visc Surg. 2015 Mar 11;pii: S1878-7886(15)00014-4. doi: 10.1016/j.jviscsurg.2015.01.013. PMID: 25770745
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Hepatology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 5 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
Elvira Manzano, 6 days ago
Treatment with two investigational, oral JAK inhibitors may be beneficial in individuals with moderate‐to‐severe alopecia areata (spot baldness), an autoimmune disease that can cause a lot of anxiety, according to an ongoing phase II study.
4 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.