Treatment Guideline Chart
Liver abscess may result from peritonitis and bowel leakage via portal circulation, direct spread from biliary disease or from hematogenous seeding.
Classical presentation includes fever, jaundice, and right upper quadrant symptoms (pain, guarding, rocking and rebound tenderness).
Biliary tract disease is the most common cause of bacterial liver abscess.
Most pyogenic liver abscesses are polymicrobial (eg enteric facultative and anaerobic species).

Liver Abscess References

  1. Chung YF, Tan YM, Lui HF, et al. Management of pyogenic liver abscesses – percutaneous or open drainage?. Singapore Med J. 2007 Dec;48(12):1158-1165. PMID: 18043848
  2. Rahimian J, Wilson T, Oram V, et al. Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis. 2004 Dec;39(11):1654-1659. PMID: 15578367
  3. Johannsen EC, Sifri CD, Madoff LC. Pyogenic liver abscesses. Infect Dis Clin North Am. 2000 Sep;14(3):547-563, vii. PMID: 10987109
  4. Salles JM, Moraes LA, Salles MC. Hepatic amebiasis. Braz J Infect Dis. 2003 Apr;7(2):96-110. PMID: 12959680
  5. Chung RT, Friedman LS. Bacterial, parasitic, and fungal infections of the liver, including liver abscess. In: Feldman M, Friedman LS, Sleisenger MH, eds. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology/diagnosis/management. 8th ed. Philadelphia: Saunders; 2006
  6. MedWorm
  7. Peralta R, Lisgaris M, Salata RA, et al. Liver abscess. eMedicine. 23 Sep 2008.
  8. Davis J, McDonald M. Pyogenic liver abscess. UpToDate. 03 Sep 2013. Accessed 18 Sep 2013.
  9. Ministry of Health Malaysia. National antibiotic guideline 2014, 2nd edition. Pharmaceutical Services Divisions, Ministry of Health Malaysia. Dec 2014. Accessed 16 Jul 2015.
  10. Lardière-Deguelte S, Ragot E, Amroun K, et al. Hepatic abscess: diagnosis and management. J Visc Surg. 2015 Mar 11;pii: S1878-7886(15)00014-4. doi: 10.1016/j.jviscsurg.2015.01.013. PMID: 25770745
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