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KELOIDS AND HYPERTROPHIC SCARS

Keloids and hypertrophic scars are abnormalities in the normal wound healing characterized by greater and more sustained extracellular matrix deposition that develops after any insult in the dermis.

It can affect the patient's quality of life, both physically and psychologically.

Hypertrophic scars are raised fibrous tissue scars that remains within the boundaries of the wound. Hypertrophic scars that resulted from surgery or trauma are called linear hypertrophic scars while those from burn injuries or extensive tissue trauma and/or infections are called widespread hypertrophic scars.

Keloids are elevated fibrous scars that extend beyond the borders of the original wound. Major keloids resulted from minor trauma while for those from genetic predisposition with autosomal-predominant features are called minor keloids.

 

 

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  2. Edriss AS, Mestak J. Management of keloid and hypertrophic scars. Ann Burns Fire Disasters. 2005 Dec;8(4):202-210. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187998/. PMID: 21991008
  3. Gauglitz GG. Management of keloids and hypertrophic scars: current and emerging options. Clin Cosmet Investig Dermatol. 2013 Apr;6:103-114. doi: 10.2147/CCID.S35252. PMID: 23637546
  4. Gold MH, Berman B, Clementoni MT, et al. Updated international clinical recommendations on scar management: part 1-evaluating the evidence. Dermatol Surg. 2014 Aug;40(8):817-824. doi: 10.1111/dsu.0000000000000049. PMID: 25068543
  5. Gold MH, McGuire M, Mustoe TA, et al. Updated international clinical recommendations on scar management: part 2-algorithms for scar prevention and treatment. Dermatol Surg. 2014 Aug;40(8):825-831. doi: 10.1111/dsu.0000000000000050. PMID: 25068544
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  14. Nast A, Eming S, Fluhr J, et al; German Society of Dermatology. German S2k guidelines for the therapy of pathological scars (hypertrophic scars and keloids). J Dtsch Dermatol Ges. 2012 Oct;10(10):747-762. doi: 10.1111/j.1610-0387.2012.08012.x. PMID: 22937806
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