Japanese%20encephalitis Treatment
Supportive Therapy
- Mode of therapy for Japanese encephalitis virus infection are symptomatic treatment, supportive care and management of complications
- There is no specific antiviral treatment for Japanese encephalitis virus infection
- Hospitalization for supportive care and close observation is generally required
- Careful nursing care and physiotherapy are needed to reduce the risk of bed sores, malnutrition and contractures
- Rest, fluids and pain relievers are used to reduce fever and relieve some symptoms
- In controlled clinical trials, corticosteroids, Interferon alpha-2a, intravenous immunoglobulin, Acyclovir or Ribavirin did not improve clinical outcome
- There are ongoing clinical studies on the efficacy of Minocycline as a treatment option
- Supportive care for Japanese encephalitis patients should be emphasized on:
- Control of intracranial pressure
- Maintenance of adequate cerebral perfusion pressure
- Seizure control
- Prevention of secondary complications