Japanese%20encephalitis Treatment

Treatment

Supportive Therapy

Mode of therapy for Japanese encephalitis virus infection are symptomatic treatment, supportive care and management of complications
There is no specific antiviral treatment for Japanese encephalitis virus infection
Hospitalization for supportive care and close observation is generally required
Careful nursing care and physiotherapy are needed to reduce the risk of bed sores, malnutrition and contractures
Rest, fluids and pain relievers are used to reduce fever and relieve some symptoms
In controlled clinical trials, corticosteroids, Interferon alpha-2a, intravenous immunoglobulin, Acyclovir or Ribavirin did not improve clinical outcome
There are ongoing clinical studies on the efficacy of Minocycline as a treatment option
Supportive care for Japanese encephalitis patients should be emphasized on:
- Control of intracranial pressure
- Maintenance of adequate cerebral perfusion pressure
- Seizure control
- Prevention of secondary complications

Rapid antigen test: Don’t let perfect be the enemy of good

Pearl Toh, 23 Oct 2021

While rapid antigen test is less sensitive than conventional nucleic acid amplification test (NAAT) such as RT-PCR* in detecting SARS-CoV-2 virus, “a test does not have to be perfect to be clinically useful,” said Professor Angela Caliendo during a session in IDWeek 2021 — echoing the maxim that perfect should not be the enemy of good in the pandemic era.

Echinocandins boost the antifungal armamentarium

Elvira Manzano, 17 Nov 2020

Invasive fungal infections, particularly those caused by Candida species, are common in hospitalized, immunocompromised, or critically ill patients and are associated with considerable morbidity and mortality.

Antimicrobial resistance: Next global, public health threat after COVID-19

Pank Jit Sin, 10 Jan 2023

As the dust settles from the SARS-CoV-2 pandemic, the lurking threat of antimicrobial resistance (AMR) once again rears its ugly head. Weighing in on this topic is Professor Dr Sasheela Sri La Sri Ponnampalavanar, Infectious Disease Professor, University Malaya Medical Centre (UMMC). Below is an excerpt from her bylined piece titled ‘Tackling the Next Global and Public Health Threat After COVID-19 – Antimicrobial Resistance (AMR).’