Ischemic stroke occurs when a blood vessel supplying the brain is obstructed.
Consider stroke in any patient presenting with sudden focal neurological deficit or any alteration in level of consciousness.
Rapid evaluation is essential for sure of time-sensitive treatments.
Determine if patient's symptoms are due to stroke and exclude stroke mimics (eg migraine, hypertensive encephalopathy, hypoglycemia, seizures or post-ictal paresis); identify other conditions requiring immediate intervention and determine the potential causes of stroke.
Asian ischaemic stroke patients with small and fragile cerebral vessels, as evidenced by the presence of multiple cerebral microbleeds (CMBs), may fare better with cilostazol than aspirin, as the former proves more effective at preventing cerebral haemorrhages especially when administered before white matter changes become extensive, according to the results of a subgroup analysis of the PICASSO* trial.
The mean heart rate during acute stroke period factors in mortality but not stroke recurrence in patients with atrial fibrillation hospitalized for acute ischaemic stroke, a study has found. Heart rate variability has no effect on both outcomes.
A target low-density lipoprotein cholesterol (LDL-C) level of <70 mg/dL appeared to reduce the risk of major cardiovascular (CV) events* following an atherosclerotic ischaemic stroke, according to results of the Treat Stroke to Target trial.
The use of thiazides appears to contribute to an increased risk of stroke in patients with type 2 diabetes, specifically in those receiving intensive blood pressure (BP) control, a recent study has found.
Endovascular treatment for ischaemic stroke produces improvements in functional outcome and other clinical, imaging and safety outcome measures. The treatment effect is similar between men and women, with the latter even having more years of healthy life, as shown in the results of two recent studies.
Post-traumatic stress disorder (PTSD) contributes to an increased risk of developing ischaemic stroke and transient ischaemic attack (TIA) in young and middle-aged individuals, independent of established risk factors, coexisting psychiatric disorders and healthcare utilization, a study has found.
The efficacy and safety of the novel oral anticoagulant edoxaban relative to warfarin for stroke prophylaxis are consistent across the full range of systolic blood pressure (SBP) in high-risk patients with atrial fibrillation (AF), according to a posthoc analysis of the ENGAGE AF-TIMI 48 trial.
Vegetarian and pescetarian diets are associated with a lower risk of ischaemic heart disease compared with a diet that include meat, according to the longitudinal EPIC*-Oxford study with 18 years of follow-up.
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.