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irritable%20bowel%20syndrome
IRRITABLE BOWEL SYNDROME
Treatment Guideline Chart
Irritable bowel syndrome is a common chronic gastrointestinal condition characterized by abdominal pain and bloating with altered bowel habits.
There are no identifiable physical, radiologic or lab abnormalities indicative of organic disease.
Symptoms may be exacerbated by stress, alcohol or food.

Irritable Bowel Syndrome References

  1. American College of Gastroenterology Functional Gastrointestinal Disorders Task Force. Evidence-based position statement on the management of irritable bowel syndrome in North America. Am J Gastroenterol. 2002 Nov;97(11)(Suppl):S1-S5. PMID: 12425585
  2. American College of Gastroenterology Task Force on Irritable Bowel Syndrome, Brandt LJ, Chey WD, Fox Orenstein AE, et al. An evidence-based position statement on the management of irritable bowel syndrome. Am J Gastroenterol. 2009 Jan;104(Suppl 1):S1-S35. doi: 10.1038/ajg.2008.122. PMID: 19521341
  3. American Gastroenterology Association. American Gastroenterological Association medical position statement: irritable bowel syndrome. Gastroenterology. 2002 Dec;123(6):2105-2107. PMID: 12454865
  4. Cash BD, Chey WD. Irritable bowel syndrome - an evidence-based approach to diagnosis. Aliment Pharmacol Ther. 2004 Jun;19(12):1235-1245. PMID: 15191504
  5. Baker DE. Rationale for using serotonergic agents to treat irritable bowel syndrome. Am J Health Syst Pharm. 2005 Apr;62(7):700-711. PMID: 15790796
  6. Brandt LJ, Bjorkman D, Fennerty B, et al. Systematic review on the management of irritable bowel syndrome in North America. Am J Gastroenterol. 2002 Nov;97(11):S7-S26. PMID: 12425586
  7. Cremonini F, Talley NJ. Diagnostic and therapeutic strategies in the irritable bowel syndrome. Minerva Med. 2004 Oct;95(5):427-441. PMID: 15467518
  8. Johanson JF. Options for patients with irritable bowel syndrome: contrasting traditional and novel serotonergic therapies. Neurogastroenterol Motil. 2004 Dec;16(6):701-711. PMID: 15601419
  9. McKenzie YA, Alder A, Anderson W, et al; Gastroenterology Specialist Group of the British Dietetic Association. British Dietetic Association evidence-based guidelines for the dietary management of irritable bowel syndrome in adults. J Hum Nutr Diet. 2012 Jun;25(3):260-274. doi: 10.1111/j.1365-277X.2012.01242.x. PMID: 22489905
  10. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology. 2002 Dec;123(6):2108-2131. PMID: 12454866
  11. Olden KW. Irritable bowel syndrome: an overview of diagnosis and pharmacologic treatment. Cleve Clin J Med. 2003 Jun;70(Suppl 2):S3-S7. PMID: 12825862
  12. Quigley EM, Abdel-Hamid H, Barbara G, et al. A global perspective on irritable bowel syndrome: a consensus statement of the World Gastroenterology Organisation Summit Task Force on irritable bowel syndrome. J Clin Gastroenterol. 2012 May;46(5):356-366. doi: 10.1097/MCG.0b013e318247157c. PMID: 22499071
  13. Mertz HR. Irritable bowel syndrome. N Engl J Med. 2003 Nov;349(22):2136-3146. PMID: 14645642
  14. Somers SC, Lembo A. Irritable bowel syndrome: evaluation and treatment. Gastroenterol Clin North Am. 2003 Jun;32(2):507-529. PMID: 12858604
  15. MedWormhttp://www.medworm.com/rss/index.php/Allergy-%26-Immunology/3/http://www.medworm.com/rss/medicalfeeds/specialities/Allergy-Immunology.xml
  16. MedWormhttp://www.medworm.com/rss/index.php/Gastroenterology/17/http://www.medworm.com/rss/medicalfeeds/specialities/Gastroenterology.xml
  17. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  18. Chun A, Desautels S, Wald A. Clinical manifestations and diagnosis of irritable bowel syndrome. UpToDate. http://www.uptodate.com/index. 05 May 2004. Accessed 23 Sep 2005.
  19. Lehrer J. Irritable bowel syndrome. eMedicine. http://www.emedicine.com/med/topic1190.htm. 29 Jun 2004. Accessed 30 Aug 2005.
  20. National Institute for Health and Care Excellence. Irritable bowel syndrome in adults: diagnosis and management of irritable bowel syndrome in primary care. NICE. http://www.nice.org.uk. 01 Feb 2008. Accessed 11 Jul 2013.
  21. Desautels S, Wald A. Treatment of irritable bowel syndrome. UpToDate. http://www.uptodate.com/index. 25 Oct 2004. Accessed 22 Sep 2005.
  22. Quigley EM, Fried M, Gwee KA, et al. World Gastroenterology Organisation Global Guideline. Irritable bowel syndrome: a global perspective. http://www.worldgastroenterology.org. Aug 2009. Accessed 11 Jul 2013.
  23. Bansal N, Sachdeva M, Pankaj J, et al. Constipation predominant irritable bowel syndrome. JIMSA. 2012 Jan;25(1):39-41. http://medind.nic.in/jav/t12/i1/javt12i1p39.pdf. Accessed 10 Apr 2014
  24. Fukudo S, Ida M, Akiho H, Nakashima Y, Matsueda K. Effect of ramosetron on stool consistency in male patients with irritable bowel syndrome with diarrhea. Clin Gastroenterol Hepatol. 2014 Jun;12(6):953-959. doi: 10.1016/j.cgh.2013.11.024. Accessed 10 Apr 2014. PMID: 24315882
  25. Quigley EM. Prucalopride: safety, efficacy and potential applications. Therap Adv Gastroenterol. 2012 Jan;5(1):23-30. doi: 10.1177/1756283X11423706. Accessed 8 Apr 2014. PMID: 22282705
  26. Weinberg DS, Smalley W, Heidelbaugh JJ, et al; American Gastroenterological Association. American Gastroenterological Association Institute guideline on the pharmacological management of irritable bowel syndrome. Gastroenterology. 2014 Nov;147(5):1146-1148. doi: 10.1053/j.gastro.2014.09.001. Accessed 25 Aug 2015. PMID: 25224526
  27. National Institute for Health and Care Excellence (NICE). Irritable bowel syndrome in adults (QS114). NICE. https://www.nice.org.uk/guidance/qs114/resources/irritable-bowel-syndrome-in-adults-75545298110149. 11 Feb 2016. Accessed 11 Apr 2016.
  28. Quigley EM, Fried M, Gwee KA, et al. World Gastroenterology Organisation global guidelines irritable bowel syndrome: a global perspective update September 2015. J Clin Gastroenterol. 2016 Oct;50(9):704-713. doi: 10.1097/MCG.0000000000000653. Accessed 6 May 2016. PMID: 27623513
  29. Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV . Gastroenterology. 2016 May;150(6):1262-1279. doi: 10.1053/j.gastro.2016.02.032. Accessed 28 Dec 2016. PMID: 27144617
  30. Lacy BE, Mearin F, Chang L, et al. Bowel disorders. Gastroenterology. 2016 May;150(6):1393-1407. doi: 10.1053/j.gastro.2016.02.031. Accessed 28 Dec 2016
  31. Ford AC, Moayyedi P, Chey WD, et al. American College of Gastroenterology monograph on management of irritable bowel syndrome. Am J Gastroenterol. 2018 Jun;113(Suppl 2):1-18. doi: 10.1038/s41395-018-0084-x. PMID: 29950604
  32. Moayyedi P, Andrews CN, MacQueen G, et al. Canadian Association of Gastroenterology clinical practice guideline for the management of irritable bowel syndrome (IBS). JCAG. 2019 Apr;2(1):6-29. doi: 10.1093/jcag/gwy071.
  33. Wald A. Clinical manifestations and diagnosis of irritable bowel syndrome in adults. UpToDate. http://www.uptodate.com. Sep 2017.
  34. Wald A. Treatment of irritable bowel syndrome in adults. UpToDate. http://www.uptodate.com. Dec 2018. Accessed 03 May 2019.
  35. American College of Gastroenterology (ACG). Irritable bowel syndrome. https://gi.org.
  36. Burbige E. Irritable Bowel Syndrome: Diagnostic approaches in clinical practice. Clin Exp Gastroenterol. 2010;3:127-137. doi: 10.2147/CEG.S12596. PMID: 21694856
  37. Camilleri M. Management options for irritable bowel syndrome. Mayo Clin Proc. 2018 Dec;93(12):1858-1872. doi: 10.1016/j.mayocp.2018.04.032. PMID: 30522596
  38. Ikechi R, Fischer BD, DeSipio J, et al. Irritable bowel syndrome: Clinical manifestations, dietary influences, and management. Healthcare (Basel). 2017 Apr;5(2):pii: E21. doi: 10.3390/healthcare5020021. PMID: 28445436
  39. McKenzie YA, Bowyer RK, Leach H, et al. (IBS Dietetic Guideline Review Group on behalf of Gastroenterology Specialist Group of the British Dietetic Association). British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet. 2016 Oct;29(5):549-75. doi: 10.1111/jhn.12385. PMID: 27272325
  40. Mounsey A, Raleigh M, Wilson A. Management of constipation in older adults. Am Fam Physician. 2015 Sep;92(6):500-4. PMID: 26371734
  41. National Institute for Health and Care Excellence. Irritable bowel syndrome in adults: Diagnosis and management of irritable bowel syndrome in primary care. NICE. http://www.nice.org.uk. 2018.
  42. National Institute for Health and Care Excellence. Irritable bowel syndrome in adults (qs114). NICE. http://www.nice.org.uk. 2018.
  43. Portincasa P, Bonfrate L, de Bari O, et al. Irritable bowel syndrome and diet. Gastroenterol Rep (Oxf). 2017 Feb;5(1):11-19. doi: 10.1093/gastro/gow047. PMID: 28110300
  44. Spiller R, Aziz Q, Creed F, et al. Guidelines on the irritable bowel syndrome: Mechanisms and practical management. Gut. 2007 Dec;56(12):1770-98. PMID: 17488783
  45. Thalheimer JC. Fiber & irritable bowel syndrome- strategies for counseling patients. Today's Dietitian. 2016 Aug;18(8):P.34. https://www.todaysdietitian.com. Accessed 23 Sep 2019
  46. Thoua NM, Murray CD. Irritable bowel syndrome. UpToDate. http://www.uptodate.com. 2011.
  47. Wilkins T, Pepitone C, Alex B, et al. Diagnosis and management of IBS in adults. Am Fam Physician. 2012 Sep;86(5):419-26. PMID: 22963061
  48. Song KH, Jung HK, Kim HJ, et al; Clinical Practice Guidelines Group Under the Korean Society of Neurogastroenterology and Motility. Clinical practice guidelines for irritable bowel syndrome in Korea, 2017 revised edition. J Neurogastroenterol Motil. 2018 Apr 30;24(2):197-215. doi: 10.5056/jnm17145. PMID: 29605976
  49. Bharucha AE, Lacy BE. Mechanisms, evaluation, and management of chronic constipation. Gastroenterology. 2020 Apr;158(5):1232-1249.e3. doi: 10.1053/j.gastro.2019.12.034. Accessed 19 Nov 2020. PMID: 31945360
  50. Farmer AD, Wood E, Ruffle JK. An approach to the care of patients with irritable bowel syndrome. CMAJ. 2020 Mar 16;192(11):E275-E282. doi: 10.1503/cmaj.190716. PMID: 32179536
  51. Wald A. Treatment of irritable bowel syndrome in adults. UpToDate. https://www.uptodate.com. 15 Jul 2020.
  52. Lacy BE, Pimentel M, Brenner DM, et al. ACG clinical guideline: management of irritable bowel syndrome. Am J Gastroenterol. 2021 Jan 1;116(1):17-44. doi: 10.14309/ajg.0000000000001036. PMID: 33315591
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