Irritable bowel syndrome is a common chronic gastrointestinal condition characterized by abdominal pain and bloating with altered bowel habits.
There are no identifiable physical, radiologic or lab abnormalities indicative of organic disease.
Symptoms may be exacerbated by stress, alcohol or food.
Treatment with the combination of pinaverium bromide plus simethicone effectively relieves abdominal pain and bloating in patients with active irritable bowel syndrome (IBS), in addition to improving stool consistency in those with constipation-predominant IBS or a mixed bowel movement pattern, according to the results of a trial.
New drug application approved by US FDA as of 01 - 15 September 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Dr Andrew Ong, a consultant at the Department of Gastroenterology & Hepatology, Singapore General Hospital, explains to Roshini Claire Anthony the challenges in diagnosing and treating irritable bowel syndrome (IBS).
Cognitive behavioural therapy (CBT), delivered over the web or phone, yields superior improvements in irritable bowel syndrome (IBS) symptoms and more favourable effects on life and mood in comparison with treatment as usual, according to data from the ACTIB* trial.
Faecal bile acids and faecal fat predict clinically relevant diarrhoea and constipation in irritable bowel syndrome (IBS) patients who may require more specific treatment rather than simple symptom management, a study has found.
Pregabalin demonstrates therapeutic potential in the treatment of irritable bowel syndrome (IBS)-related abdominal pain, bloating and diarrhoea but not constipation, according to the results of a trial.
Negatively perceived events during adulthood are associated with a heightened risk of irritable bowel syndrome (IBS), worse symptom severity and quality of life, and dysregulated stress response, a study suggests.
Among patients with irritable bowel syndrome (IBS), those with functional dyspepsia appear to have increased gastrointestinal symptoms both before and after a liquid meal with lactulose, a study has shown.
There appears to be no greater early childhood gastrointestinal infections rates among adult individuals with irritable bowel syndrome (IBS) compared with adult controls, according to a study, which does not support a statistically significant association between early life infections and IBS aside from bronchitis.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).