Influenza may present as a mild respiratory illness similar to the common cold or it may present without characteristic signs and symptoms.
The main type of influenza virus are types A, B & C virus. Types A&B are the main causes of influenza outbreaks.
Patient may appear flushed and have pain on eye movement. Non-exudative pharyngitis, scattered rales or rhonchi may be present.
Oseltamivir appears to have similar efficacy as peramivir in the treatment of young children with severe influenza B, a study has found. However, oseltamivir treatment leads to better recovery and shorter hospitalization in children with severe influenza A.
Prompt empiric antiviral treatment in children hospitalized for influenza and with high-risk medical conditions or in children admitted to an intensive care unit (ICU) leads to early discharge, as shown in a study.
Children who are fully vaccinated against the flu, ie, receive the recommended number of influenza vaccine doses, have a lower risk of acquiring influenza compared with those who are partially vaccinated, a US study found.
Influenza burden in Singapore has been on the rise since 2010, with young children (aged ≤4 years) and the elderly (aged ≥65 years) being most susceptible to influenza‐associated hospitalization for pneumonia and influenza (P&I), a local study has shown.
Early administration of anti-influenza medications in children with tracheostomy cuts the length of stay in the hospital by a day, although these children continue to receive antibiotics even after detection and treatment of their viral infections, a study has shown.
New drug applications approved by US FDA as of 16 - 31 October 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Respiratory infections, particularly influenza, may increase the risk of treatment failure in children with asthma who present to emergency departments (EDs) with exacerbations, a secondary analysis of the DOORWAY* study revealed.